Brain Center Rudolf Magnus is the research body of ‘UMC Utrecht Hersencentrum’. Our mission is to perform high-level research in clinical and experimental neuroscience, whilst delivering an exceptional standard of care.
Prof. dr. Marian Joels is director of the Brain Center Rudolf Magnus and chair of the focal area Brain of the UMC Utrecht. Her research focuses on the effects of stress in the brain.
Our researchers in the area of Stroke work to identify genetic and environmental risk factors that determine vulnerability in patients. We also search for novel treatments to aid in recovery post-stroke. Practitioners, starting at the bedside, directly carry much of our research out.
The Epilepsy research team uses multiple approaches to uncover the complex interplay between genetic and environmental factors that contribute to the development of refractory epilepsy. Through this approach, we work toward finding novel treatment options for refractory Epilepsy in children and adults.
UMC Utrecht has been official selected by the NFU as a center of expertise for rare epilepsy for children: the Center for Refractory Pediatric Epilepsy. Diseases that are included are: Rare epilepsy, Tuberous Sclerosis, Continuous spikes and waves during sleep and ESES, Genetic causes of refractory pediatric epilepsy.
Within the research team Neuromuscular Disorders, we face deeply complex and challenging questions. Hand in hand with our patients, we unravel the disease mechanisms of these disorders, our aim is to deliver effective treatments, quickly. Our approach is characterized by intense interactions between clinical and preclinical investigators.
UMC Utrecht has been official selected by the NFU as a center of expertise for neuromuscular diseases: the Brain Centre Rudolf Magnus Neuromuscular Diseases. Diseases that are included are: ALS, PLS, PSMA, en Polyneuropathy.
Our research team focuses on unraveling the mechanisms that underlie psychotic disorders. We strive toward developing new clinical assessments and treatments, and draw on all approaches to further our understanding of the intersection between biological and psychosocial factors.
The team of researchers in the area of Developmental Disorders are building on UMC Utrecht’s long history in research of developmental disorders such as ADHD and autism. We utilize advanced clinical diagnostic tools that combined with genetic approaches, neuroimaging and cognitive psychology help to uncover the developmental, neurobiological pathways underlying complex developmental disorders.
In a joint venture with Philips Medical Systems -and supported by Utrecht University, the UMC Utrecht and the Netherlands Organisation for Scientific Research-, a 7T brain scanner was implemented at the UMC Utrecht in 2007. Since then Peter Luijten and his team of MR physicists, radiologists and neuroscientists has continuously improved hardware and software of the scanner. Today, this scanner is among the best-functioning 7T scanners worldwide and already used for clinical purposes.
Nick Ramsey runs a lab where the latest developments in imaging brain activity, machine learning techniques and microsystems technology merge. His team of engineers, fMRI-experts and cognitive neuroscientists work on two major projects, at least until 2018. The first: putting years of technical innovation to the test, trying to enable five paralyzed patients to operate a computer with their thoughts, in the Utrecht Neural Prosthesis (UNP) project.
The second project is called iCONNECT, for which Ramsey received a personal ERC Advanced grant of 2.5 million Euro. In iCONNECT, Ramsey’s group explores brain patterns and develops decoding strategies, using 7 Tesla MRI and electrocorticography. The aim is a brain computer interface-system that interprets activity patterns on the surface of the brain, in real-time.
UMC Utrecht Brain Center Rudolf Magnus
3584 CG Utrecht
Brain structure in bipolar disorder – a longitudinal neuroimaging study in twins