Prof. Jan Veldink has received an ERC consolidator grant of two million euros. With the help of this grant in the next five years he will investigate why some changes in the DNA lead to ALS in one person and not in the other.

Veldink will investigate the interaction between different DNA variations within one person and also the interaction with environmental exposures from the past. The genetic data for this research will come from an other project he coordinates, Project MinE.
The results of the study will enable carriers of these DNA abnormalities to receive more precise information about their risk of getting ALS. Veldink will further investigate the most important DNA abnormalities in nerve cells in culture that have been obtained from the patient's skin and blood cells. With this he hopes to be able to make models that are suitable for the development of new treatments.