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dr. J.A.G. van Roon Associate Professor

dr. J.A.G. van Roon Associate Professor

Associate Professor
dr. J.A.G. van Roon Associate Professor
  • Rheumatology & Clinical Immunology

Research Programs

Infection & Immunity

Research Output (152)

Leflunomide/hydroxychloroquine combination therapy targets type I IFN-associated proteins in patients with Sjögren's syndrome that show potential to predict and monitor clinical response

Hamkour Safae, van der Heijden Eefje Hm, Lopes Ana P, Blokland Sofie L M, Bekker Cornelis P J, Van Helden-Meeuwsen Cornelia G, Versnel Marjan A, Kruize Aike A, Radstake Timothy Rdj, Leavis Helen L, Hillen Maarten R, van Roon Joel Ag 2 Aug 2023, In: RMD Open. 9 8 p.

CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjögren’s Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells

Hinrichs Anneline C., Kruize Aike A., Lafeber Floris P.J.G., Leavis Helen L., van Roon Joel A.G. Aug 2023, In: International Journal of Molecular Sciences. 24

Deciphering the role of cDC2s in Sjögren's syndrome:transcriptomic profile links altered antigen processes with IFN signature and autoimmunity

Lopes Ana P, Hillen Maarten R, Hinrichs Anneline C, Blokland Sofie Lm, Bekker Cornelis Pj, Pandit Aridaman, Kruize Aike A, Radstake Timothy Rdj, van Roon Joel A 28 Sep 2022, In: Annals of the Rheumatic Diseases. 82 , p. 374-383 10 p.

Mechanisms underlying DMARD inefficacy in difficult-to-treat rheumatoid arthritis:a narrative review with systematic literature search

Roodenrijs Nadia M.T., Welsing Paco M.J., van Roon Joël, Schoneveld Jan L.M., van der Goes Marlies C., Nagy György, Townsend Michael J., van Laar Jacob M. 30 Aug 2022, In: Rheumatology (Oxford, England). 61 , p. 3552-3566 15 p.

CCL5 Release by CCR9+ CD8 T Cells:A Potential Contributor to Immunopathology of Primary Sjögren’s Syndrome

Hinrichs Anneline C., Blokland Sofie L.M., Kruize Aike A., Lafeber Floris P.J., Leavis Helen L., van Roon Joel A.G. 1 Jun 2022, In: Frontiers in Immunology. 13 , p. 1-10

The Role of Interleukin-4 and Interleukin-10 in Osteoarthritic Joint Disease:A Systematic Narrative Review

van Helvoort E M, van der Heijden E, van Roon J A G, Eijkelkamp N, Mastbergen S C 1 Apr 2022, In: Cartilage. 13 , p. 1-14

CXCL4 drives fibrosis by promoting several key cellular and molecular processes

Affandi Alsya J, Carvalheiro Tiago, Ottria Andrea, de Haan Judith J, Brans Maike A D, Brandt Maarten M, Tieland Ralph G, Lopes Ana P, Fernández Beatriz Malvar, Bekker Cornelis P J, van der Linden Maarten, Zimmermann Maili, Giovannone Barbara, Wichers Catharina G K, Garcia Samuel, de Kok Michael, Stifano Giuseppina, Xu Yan Juan, Kowalska M Anna, Waasdorp Maaike, Cheng Caroline, Gibbs Susan, de Jager Saskia C A, van Roon Joel A G, Radstake Timothy R D J, Marut Wioleta 4 Jan 2022, In: Cell Reports. 38

The Transcriptomic Profile of Monocytes from Patients With Sjögren's Syndrome Is Associated With Inflammatory Parameters and Is Mimicked by Circulating Mediators

Lopes Ana P, Bekker Cornelis P J, Hillen Maarten R, Blokland Sofie L M, Hinrichs Anneline C, Pandit Aridaman, Kruize Aike A, Radstake Timothy R D J, van Roon Joel A G 3 Aug 2021, In: Frontiers in Immunology. 12

Transcriptome Analysis of CCR9+ T Helper Cells From Primary Sjögren's Syndrome Patients Identifies CCL5 as a Novel Effector Molecule

Hinrichs Anneline C, Blokland Sofie L M, Lopes Ana P, Wichers Catharina G K, Kruize Aike A, Pandit Aridaman, Radstake Timothy R D J, van Roon Joel A G 27 Jul 2021, In: Frontiers in Immunology. 12

All research output

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