Genetics helps sarcoidosis patients

Small variations in the DNA among patients with sarcoidosis have an effect on the course of the disease.

In his doctoral thesis, Adrian Kruit explains that this insight can make detecting the disease easier and its treatment more effective. Sarcoidosis is a disease in which inflammation can develop in various organs, and some of these patients develop severe scarring in the lungs (lung fibrosis). Differences in the DNA known as single nucleotide polymorphisms (SNPs) determine to what degree a sarcoidosis patient is at risk of developing lung fibrosis.

Adrian Kruit received his PhD from Utrecht University on September 27. His thesis is titled 'Gene polymorphisms in fibrotic sarcoidosis'.