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Key publications

2009

Limitations and possibilities of small RNA digital gene expression profiling.
Linsen SE, de Wit E, Janssens G, Heater S, Chapman L, Parkin RK, Fritz B, Wyman SK, de Bruijn E, Voest EE, Kuersten S, Tewari M, Cuppen E. Nat Methods. 2009 Jul;6(7):474-6 (2009)
 
Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity.
Dansen TB, Smits LM, van Triest MH, de Keizer PL, van Leenen D, Koerkamp MG, Szypowska A, Meppelink A, Brenkman AB, Yodoi J, Holstege FC, Burgering BM. Nat Chem Biol. 2009 Sep;5(9):664-72. Epub 2009 Aug 2 (2009)
 
Direct spatial control of Epac1 by cyclic AMP.
Ponsioen B, Gloerich M, Ritsma L, Rehmann H, Bos JL, Jalink K. Mol Cell Biol. 2009 May;29(10):2521-31 (2009)

Distinct promoter dynamics of the basal transcription factor TBP across the yeast genome.
van Werven FJ, van Teeffelen HA, Holstege FC, Timmers HT. Nat Struct Mol Biol. 2009 Oct;16(10):1043-8. Epub 2009 Sep 20 (2009)

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.
van Es MA, Veldink JH, Saris CG, Blauw HM, van Vught PW, Birve A, Lemmens R, Schelhaas HJ, Groen EJ, Huisman MH, van der Kooi AJ, de Visser M, Dahlberg C, Estrada K, Rivadeneira F, Hofman A, Zwarts MJ, van Doormaal PT, Rujescu D, Strengman E, Giegling I, Muglia P, Tomik B, Slowik A, Uitterlinden AG, Hendrich C, Waibel S, Meyer T, Ludolph AC, Glass JD, Purcell S, Cichon S, Nöthen MM, Wichmann HE, Schreiber S, Vermeulen SH, Kiemeney LA, Wokke JH, Cronin S, McLaughlin RL, Hardiman O, Fumoto K, Pasterkamp RJ, Meininger V, Melki J, Leigh PN, Shaw CE, Landers JE, Al-Chalabi A, Brown RH Jr, Robberecht W, Andersen PM, Ophoff RA, van den Berg LH.  Nat Genet. 2009 Oct;41(10):1083-7. Epub 2009 Sep 6 (2009)