Name
Patrick de Zeeuw, M.Sc.
Department of Psychiatry
Section Brain Changes in Developmental Disorders
Function
PhD-student
E-mail: p.dezeeuw@umcutrecht.nl
Telephone number: 088 - 75 59641
Supervisor
Prof. Dr. H. van Engeland, Dr. S. Durston
Title research
Profiling ADHD: Longitudinal structural MRI and DTI in ADHD and controls.
Summary research
The aim of the project is to integrate sturctural neuroimaging, cognitive performance and genotypic information in ADHD. To achieve this, a large group of children with ADHD and controls will be scanned using both structural Magnetic Resonance Imaging and Diffusion Tensor Imaging (DTI). Additionally, tests tapping cognitive functions which are known to be deficient in ADHD will be administered. DNA will be obtained from participants and their parents for genotyping of genes which have been implicated in ADHD, mainly DAT1 and DRD4. Of main interest is describing brain development in ADHD, as well as the influence of genetic vulnerability and presence of cognitive deficits on brain development in ADHD.
Publications
De Zeeuw, P., Aarnoudse-Moens, C., Bijlhout, J., König, C., Post Uiterweer, A., Papanikolau, A., Hoogenraad, C., Iemandt, L., De Been, D., Sergeant, J.A., & Oosterlaan, J. (2008). Inhibitory Performance, Response Speed, Intra-Individual Variability, and Response Accuracy in ADHD. Journal of The American Academy of Child and Adolescent Psychiatry. 47(7)