Name: Maarten Pennings
Date of birth:
12-06-1970
Educational background:
HBO: Biotechnology
Promotion:
Platelet receptors involved in the antiphospholipid syndrome
Function:
Post-Doc
Working at the department since:
15-06-2011
Supervisor(s):
R.T. Urbanus
Projects you are working on, most important tasks: The role of β2-GPI in the antiphospholipid syndrome
Major publications:
- The lipopolysaccharide biosynthesis locus of Campylobacter jejuni 81116. B. N Fry, V Korolik, JA ten Brinke, MTT. Pennings, R. Zalm, BJ. Teunis, PJ. Coloe, BA van der Zeijst. Microbiology 1998; 44, 2049-2061.
- β2-glycoprotein I and LDL-receptor family members PG de Groot, M. van Lummel, MTT. Pennings, RT. Urbanus, B. de Laat, PJ. Lenting, RHWM. Derksen.. Thrombosis Research 2005; 114(5)-455-459.
- Pathogenic anti-β2-glycoprotein I antibodies recognize domain I of β2-glycoprotein I only after a conformational change. B. de Laat, RHWM Derksen, M. van Lummel, MTT. Pennings, PG de Groot. Blood 2006; 1(107-5), 1916-1924.
- The binding site in β2-glycoprotein I for ApoER2' on platelets is located in domain V. MTT. Pennings, M. van Lummel, RHWM. Derksen, RT. Urbanus, BCH. Lutters, N. Kaldenhoven, PG de Groot. Journal of Biological Chemistry 2006; 4(280-44), 36729-36736.
- Interaction of β2-glycoprotein I with members of the Low Density Lipoprotein receptor family. MTT. Pennings, M. van Lummel, RHWM. Derksen, E. Westein, PJ. Lenting, PG de Groot. Journal of Thrombosis and Heamostasis 2006; Aug;4(8):1680-90.
- Platelet adhesion to dimeric β2-glycoprotein-I under conditions of flow is mediated by at least two receptors: Glycoprotein Ib-alpha and ApoER2’. MTT. Pennings, RHWM Derksen, M. van Lummel, WL. Tekelenburg, J. Adelmeijer, K. vanHoorelbeke, RT. Urbanus, T. Lisman, PG de Groot. J. Thromb. Heamost. 2007;5:369-377
- Platelets express three different splice variants of ApoER2 that are all involved in signaling. MTT Pennings, RHWM. Derksen, RT. Urbanus, WL. Tekelenburg, W. Hemrika, PG. de Groot. J Thromb Haemost 2007;5(7):1538-44.
- Biomarkers in the diagnosis of food allergy. Dermatologie in vogelvlucht. 2010. MTT.Pennings. UMC Utrecht uitgave, Dept. Dermatology & Allergology
- Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome. Z. Romay-Penabad, R. Aguilar-Valenzuela, RT. Urbanus , RH. Derksen, MTT. Pennings, E. Papalardo, T. Shilagard, G. Vargas, Y. Hwang, PG. de Groot, SS. Pierangeli. Blood. 2010 Nov 30. [Epub ahead of print]
What special knowledge of yours could be of interest to your colleagues?Molecular biology, cell culture, biochemistry, IHC, confocal microscopy
E-mail:
m.pennings@umcutrecht.nl