Wigard Kloosterman currently holds a position as a senior postdoc in the lab of Prof. Edwin Cuppen in the Research section of the Dept. of Medical Genetics, UMC Utrecht. He is coordinating all the next-generation sequencing projects in the lab, making use of the SOLiD sequencing platform (Applied Biosystems), which was implemented in the lab in the autumn of 2009.
The SOLiD sequencer has a variety of application areas, such as transcriptome sequencing, methylation profiling, and SNP/mutation discovery. Dr. Kloosterman’s research is primarily focused on the analysis of structural genomic variation such as deletions, insertions, translocations and copy-number changes and on the relation of structural variation to disease. A second research line comprises the development and implementation of novel genomic enrichment technology and the application of this technology in both fundamental and diagnostically oriented, large-scale, resequencing projects.
Wigard Kloosterman received his MSc in Biotechnology from the University of Groningen (1998). In 2003, he started his PhD in the lab of Dr. Ronald Plasterk at the Hubrecht Institute, where he studyied the expression and function of microRNAs in embryonic development. After completing his PhD, he worked for two years as a scientist at the DSM Biotechnology Centre in Delft.
EmailPublications in PubMed