Techniques

Bioinformatics
In our research we produce a huge amount of data, such as genome-wide genotypes, gene expression data and sequencing data. These amounts cannot be analyzed without proper bioinformatic tools. We require people who can master statistical methods and have a biological mindset to decipher diseases in a mathematical fashion.
Contact: Dr. Roel Ophoff


Next-generation sequencing
Next-generation sequencing offers rapid ways for the genome-wide detection of single nucleotide polymorphisms and structural variation, mRNA profiling, and identification of transcription factor binding sites. It is also being applied in medical genomics to resequence loci that are associated with disease and it will probably be implemented in diagnostics for the quick and thorough genotyping of patients’ DNA. ... see Personal Genomics
Contact: Dr. Wigard Kloosterman or Dr. Edwin Cuppen