1: Steller EJ, Ritsma L, Raats DAE, Hoogwater FJH, Emmink BL, Govaert KM, Laoukili J, Borel Rinkes IHM, van Rheenen J and Kranenburg O.
The death receptor CD95 activates the cofilin pathway to stimulate tumor cell invasion. EMBO Reports 2011 in press.
2: Raats DA, de Bruijn MT, Steller EJ, Emmink BL, Borel-Rinkes IH, Kranenburg O. Synergistic killing of colorectal cancer cells by oxaliplatin and ABT-737.
Cell Oncol. 2011 in press
3: Emmink BL, Van Houdt WJ, Vries RG, Hoogwater FJ, Govaert KM, Verheem A, Nijkamp MW, Steller EJ, Jimenez CR, Clevers H, Rinkes IH, Kranenburg O.
Differentiated Human Colorectal Cancer Cells Protect Tumor-Initiating Cells from Irinotecan. Gastroenterology. 2011 in press
4: Nijkamp MW, Hoogwater FJ, Steller EJ, Westendorp BF, van der Meulen TA,
Leenders MW, Borel Rinkes IH, Kranenburg O.
CD95 is a key mediator of invasion and accelerated outgrowth of mouse colorectal liver metastases following radiofrequency ablation.
J Hepatol. 2010 Dec;53(6):1069-77.
5: van Houdt WJ, Hoogwater FJ, de Bruijn MT, Emmink BL, Nijkamp MW, Raats DA, van der Groep P, van Diest P, Borel Rinkes IH, Kranenburg O.
Oncogenic KRAS desensitizes colorectal tumor cells to epidermal growth factor receptor inhibition and activation.
Neoplasia. 2010 Jun;12(6):443-52.
6: van Houdt WJ, de Bruijn MT, Emmink BL, Raats D, Hoogwater FJ, Borel Rinkes IH, Kranenburg O.
Oncogenic K-ras activates p38 to maintain colorectal cancer cell proliferation during MEK inhibition.
Cell Oncol. 2010 Jan 1;32(4):245-57.
7: de Bruijn MT, Raats DA, Hoogwater FJ, van Houdt WJ, Cameron K, Medema JP,
Borel Rinkes IH, Kranenburg O.
Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa.
Br J Cancer. 2010 Apr 13;102(8):1254-64.
8: Hoogwater FJ, Nijkamp MW, Smakman N, Steller EJ, Emmink BL, Westendorp BF, Raats DA, Sprick MR, Schaefer U, Van Houdt WJ, De Bruijn MT, Schackmann RC, Derksen PW, Medema JP, Walczak H, Borel Rinkes IH, Kranenburg O. Oncogenic K-Ras turns death receptors into metastasis-promoting receptors in human and mouse colorectal cancer cells. Gastroenterology. 2010 Jun;138(7):2357-67.
9: Smakman N, van den Wollenberg DJ, Elias SG, Sasazuki T, Shirasawa S, Hoeben
RC, Borel Rinkes IH, Kranenburg O. KRAS(D13) Promotes apoptosis of human
colorectal tumor cells by ReovirusT3D and oxaliplatin but not by tumor necrosis
factor-related apoptosis-inducing ligand.
Cancer Res. 2006 May 15;66(10):5403-8.
10: Smakman N, Borel Rinkes IH, Voest EE, Kranenburg O. Control of colorectal metastasis formation by K-Ras.
Biochim Biophys Acta. 2005 Nov 25;1756(2):103-14.