Klei, WA van

Wilton van Klei

Name: W.A. (Wilton) van Klei, MD, PhD  
Function: Associate Professor and staff Anesthesiology
Department: Anesthesiology
Division: Division of Anesthesiology, Intensive Care and Emergency Medicine
E-mail address: W.A.vanKlei@umcutrecht.nl
Phone number: +31 (0) 88 75 59677
Fax number: +31 (0) 30 254 1828
Visiting address: UMC Utrecht
Heidelberglaan 100
3584 CX Utrecht
The Netherlands
Correspondence: UMC Utrecht
P.O. Box 85500
Mail stop Q04.2.313
3508 GA Utrecht
The Netherlands
After obtaining his Masters in clinical epidemiology (2001) and his PhD on preoperative evaluation (2002), Wilton van Klei completed his postgraduate training in anesthesiology in 2006. He subsequently did a one-year fellowship in perioperative medicine at the Ottawa Hospital / University of Ottawa (Canada). After his return to the UMC Utrecht in 2007, he became a staff anesthesiologist and the medical director of the outpatient preoperative evaluation clinic of the UMC Utrecht. He also completed a fellowship in cardiothoracic anesthesia (2009).

Interest and focus
Wilton is involved in various multidisciplinary clinical research projects that aim to further improve perioperative care. To this aim, he is investigator in several prospective and many retrospective studies.

Examples of current research are the development of interventions to reduce the incidence of (silent) postoperative myocardial ischemia and infarction (with cardiologists and epidemiologists), the incidence and severity of cognitive decline after non-cardiac surgery in geriatric patients (with nursing scientists) and the effects of several different types of co-medication on outcome (with hospital pharmacists).

An example of a past project is the Outpatient Preoperative Evaluation by Nurses study, a prospective diagnostic study (N=4,400). It quantified the accuracy of trained nurses to correctly assess the preoperative health status of surgical patients as compared to anesthesiologists. Another example is the IMPACT trial, a prospective study (N=12,000) that evaluated the effects of implementation in daily practice of a prediction rule to predict postoperative nausea and vomiting on physician behavior.
Past retrospective research projects that used data obtained automatically from the electronic records in use at the UMCU include some projects on the effects of intra-operative hypotension on postoperative outcomes (stroke, death) and a project that used the results of an ECG obtained before surgery to predict the occurrence of a postoperative myocardial infarction.
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