prof.dr.ir. E.P.J.G. Cuppen

Specialisme: Medische Genetica
Afdeling: Afdeling Menselijke Genetica
Divisies: Biomedische Genetica

Contact

E-mail: ecuppen@umcutrecht.nl
Telefoon: (+31) 88 756 8312

De hoogleraar uitgelicht

Biografie

Externe erkenningen:

European Young Investigator Award 2005

Onderzoek

Key Publications:

• Linsen SE, de Wit E, Janssens G, Heater S, Chapman L, Parkin RK, Fritz B,Wyman SK, de Bruijn E, Voest EE, Kuersten S, Tewari M, Cuppen E.(2009). Limitations and possibilities of small RNA digital gene expression profiling. Nat Methods 6:474-476.
• Guryev, V., Saar, K., Adamovic, T., Verheul, M., van Heesch, S., Cook, S.,Pravenec, M., Aitman, T., Jacob, H., Shull, JD., Hubner, N., and Cuppen, E. (2008). Distribution and functional impact of DNA copy number variation in the rat. Nature Genetics, 40:538-545.
• Cuppen, E., Gort, E., Hazendonk, E., Mudde, J., v.d. Belt, J., Nijman, I.J., Guryev, V., and Plasterk, R.H.A. (2007). Efficient target-selected mutagenesis in Caenorhabditis elegans: towards a knockout for everygene. Genome Research, 17:649-658.
• Guryev, V., Smits, B.M.G., van de Belt, J., Verheul, M., Hubner, N., and Cuppen, E. (2006). Haplotype block structure is conserved across mammals. PLOS Genetics, 2(7): e121.
• Smits, B.M.G., van Zutphen, B.F.M., Plasterk, R.H.A, and Cuppen, E.(2004) Genetic variation in coding regions between and within commonly used inbred rat strains. Genome Research, 14:1285-1290.
• Berezikov, E., Guryev, V., Belt, J. v.d., Wienholds, E., Plasterk, R.H.A, and Cuppen, E. (2005). Phylogenetic shadowing and computational identification of human microRNA genes. Cell, 120:21-24.

Nevenfuncties:

• Stafwetenschapper van het Hubrecht Instituut
• Professor Genoom Biologie, Faculteit van de Beta Wetenschappen, Afdeling Biologie
• Stichter en adviseur(CSO) InteRNA Technologies B.V.
• Adviseur Philips Research