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prof. dr. F.W. (Folkert) Asselbergs

Full Professor
prof. dr. F.W. (Folkert) Asselbergs
  • Division of Heart & Lungs

Research Programs

Circulatory Health

Biography

Biography

Prof Folkert W. Asselbergs is Prof in cardiovascular genetics and consultant cardiologist at the department of Cardiology, University Medical Center Utrecht, Prof of Precision medicine at the Institute of Cardiovascular Science and Institute of Health Informatics, University College London, Director BRC Clinical Research Informatics Unit, University College London Hospital, Manager Research Center for Circulatory Health, UMC Utrecht, and chair data infrastructure Dutch Cardiovascular Alliance (www.dcvalliane.nl).

 

Professor Asselbergs published more than 300 scientific papers in the field of cardiovascular disease and his work has been funded by the Netherlands Heart Foundation, Netherlands Heart Institute, British Heart Foundation, leDucq Foundation, EU FP7, European Society of Cardiology, BBMRI, National Institutes of Health, Innovative Medicines Initiative, European Research Area Network on Cardiovascular Diseases and ZonMw.

 

His research program in complex genetics focuses on the discovery of genes influencing susceptibility to cardiovascular disease; the application of these findings for the validation of drug targets; and the use of genetic tests for treatment targeting (stratified medicine). Lately, he widened his research focus to precision medicine using linked data sources such as wearable information and routine care data obtained from electronic health records including free text. His ambition is to build a network for performing clinical trials within routine health care linked to national registries. 

 

Prof Asselbergs is member of a large number of consortia and (co-) founded several consortia of which igenetrain (www.igenetrain.net), and GENIUS-CHD (www.genius-chd.org) are the most prominent ones. He is scientific coordinator of European IMI Bigdata@Heart consortium (www.bigdata-heart.eu). BigData@Heart aims to deliver clinically relevant disease cardiovascular phenotypes, scalable insights from real-world evidence including data from registries, wearables and electronic health records, and insights driving drug development and personalized medicine through advanced big-data analytics. 

 

 

 

 

Side Activities

    • Prof of Precision medicine at the Institute of Cardiovascular Science and Institute of Director
    • Director Clinical Research Informatics Unit, University College London HospitalHealth Informatics, University College London
    • Medical Scientific Board Member "Deep".
    • Manager Research Center for Circulatory Health, UMC Utrecht

Fellowship and Awards

  • 2014 - Dr. E. Dekker Scholarship of the Netherlands Heart Foundation (2014T001)

    2012 - Fellow of the European Society of Cardiology

    2010 - Clinical fellowship from the Netherlands Organisation for Health Research and Development(ZonMw grant 90700342)

    2003  - Dr. E. Dekker Scholarship of the Netherlands Heart Foundation(NHS 2003T010)

Research Output (362)

Sex Differences in the Risk of Coronary Heart Disease Associated With Type 2 Diabetes:A Mendelian Randomization Analysis

Peters Tricia M, Holmes Michael V, Richards J Brent, Palmer Tom, Forgetta Vincenzo, Lindgren Cecilia M, Asselbergs Folkert W, Nelson Christopher P, Samani Nilesh J, McCarthy Mark I, Mahajan Anubha, Davey Smith George, Woodward Mark, O'Keeffe Linda M, Peters Sanne A E feb 2021, In: Diabetes Care. 44 , p. 556-562 7 p.

Risk Factors and Prevalence of Dilated Cardiomyopathy in Sub-Saharan Africa:Protocol for a Systematic Review

Fundikira Lulu Said, Chillo Pilly, van Laake Linda W, Mutagaywa Reuben Kato, Schmidt Amand Floriaan, Kamuhabwa Appolinary, Kwesigabo Gideon, Asselbergs Folkert W 21 jan 2021, In: JMIR Research Protocols. 10 , p. e18229

Temporal Evolution of Serum Concentrations of High-Sensitivity Cardiac Troponin During 1 Year After Acute Coronary Syndrome Admission

van den Berg Victor J, Oemrawsingh Rohit M, Umans Victor A W M, Kardys Isabella, Asselbergs Folkert W, van der Harst Pim, Hoefer Imo E, Kietselaer Bas, Lenderink Timo, Oude Ophuis Anton J, van Schaik Ron H, de Winter Robbert J, Akkerhuis K Martijn, Boersma Eric, 5 jan 2021, In: Journal of the American Heart Association. 10 , p. e017393

Sex, Age, and Socioeconomic Differences in Nonfatal Stroke Incidence and Subsequent Major Adverse Outcomes

Akyea Ralph K, Vinogradova Yana, Qureshi Nadeem, Patel Riyaz S, Kontopantelis Evangelos, Ntaios George, Asselbergs Folkert W, Kai Joe, Weng Stephen F jan 2021, In: Stroke. 52 , p. 396-405 10 p.

Sudden Cardiac Death Prediction in Arrhythmogenic Right Ventricular Cardiomyopathy:A Multinational Collaboration

Cadrin-Tourigny Julia, Bosman Laurens P, Wang Weijia, Tadros Rafik, Bhonsale Aditya, Bourfiss Mimount, Lie Øyvind H, Saguner Ardan M, Svensson Anneli, Andorin Antoine, Tichnell Crystal, Murray Brittney, Zeppenfeld Katja, van den Berg Maarten P, Asselbergs Folkert W, Wilde Arthur A M, Krahn Andrew D, Talajic Mario, Rivard Lena, Chelko Stephen, Zimmerman Stefan L, Kamel Ihab R, Crosson Jane E, Judge Daniel P, Yap Sing-Chien, Van der Heijden Jeroen F, Tandri Harikrishna, Jongbloed Jan D H, van Tintelen J Peter, Platonov Pyotr G, Duru Firat, Haugaa Kristina H, Khairy Paul, Hauer Richard N W, Calkins Hugh, Te Riele Anneline S J M, James Cynthia A jan 2021, In: Circulation. Arrhythmia and electrophysiology. 14 , p. e008509

Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank

Olafsdottir Thorhildur, Thorleifsson Gudmar, Sulem Patrick, Stefansson Olafur A, Medek Helga, Olafsson Karl, Ingthorsson Orri, Gudmundsson Valur, Jonsdottir Ingileif, Halldorsson Gisli H, Kristjansson Ragnar P, Frigge Michael L, Stefansdottir Lilja, Sigurdsson Jon K, Oddsson Asmundur, Sigurdsson Asgeir, Eggertsson Hannes P, Melsted Pall, Halldorsson Bjarni V, Lund Sigrun H, Styrkarsdottir Unnur, Steinthorsdottir Valgerdur, Gudmundsson Julius, Holm Hilma, Tragante Vinicius, Asselbergs Folkert W, Thorsteinsdottir Unnur, Gudbjartsson Daniel F, Jonsdottir Kristin, Rafnar Thorunn, Stefansson Kari 1 dec 2020, In: Communications biology. 3 , p. 129

Functional investigation of the coronary artery disease gene SVEP1

Winkler Michael J, Müller Philipp, Sharifi Amin M, Wobst Jana, Winter Hanna, Mokry Michal, Ma Lijiang, van der Laan Sander W, Pang Shichao, Miritsch Benedikt, Hinterdobler Julia, Werner Julia, Stiller Barbara, Güldener Ulrich, Webb Tom R, Asselbergs Folkert W, Björkegren Johan L M, Maegdefessel Lars, Schunkert Heribert, Sager Hendrik B, Kessler Thorsten dec 2020, In: Basic Research in Cardiology. 115 , p. 67

Cardiac complications in patients hospitalised with COVID-19

Linschoten Marijke, Peters Sanne, van Smeden Maarten, Jewbali Lucia S, Schaap Jeroen, Siebelink Hans-Marc, Smits Peter C, Tieleman Robert G, van der Harst Pim, van Gilst Wiek H, Asselbergs Folkert W, dec 2020, In: European Heart Journal. Acute Cardiovascular Care. 9 , p. 817-823 7 p.

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

Surendran Praveen, Feofanova Elena V., Lahrouchi Najim, Ntalla Ioanna, Karthikeyan Savita, Cook James, Chen Lingyan, Mifsud Borbala, Yao Chen, Kraja Aldi T., Cartwright James H., Hellwege Jacklyn N., Giri Ayush, Tragante Vinicius, Thorleifsson Gudmar, Liu Dajiang J., Prins Bram P., Stewart Isobel D., Cabrera Claudia P., Eales James M., Akbarov Artur, Auer Paul L., Bielak Lawrence F., Bis Joshua C., Braithwaite Vickie S., Brody Jennifer A., Daw E. Warwick, Warren Helen R., Drenos Fotios, Nielsen Sune Fallgaard, Faul Jessica D., Fauman Eric B., Fava Cristiano, Ferreira Teresa, Foley Christopher N., Franceschini Nora, Gao He, Giannakopoulou Olga, Giulianini Franco, Gudbjartsson Daniel F., Guo Xiuqing, Harris Sarah E., Havulinna Aki S., Helgadottir Anna, van der Harst Pim, Vaartjes Ilonca, Asselbergs Folkert W., Bots Michiel L., van der Harst Pim, van der Meer Peter, , , , , dec 2020, In: Nature Genetics. 52 , p. 1314-1332 19 p.

Prediction of vascular aging based on smartphone acquired PPG signals

Dall'Olio Lorenzo, Curti Nico, Remondini Daniel, Safi Harb Yosef, Asselbergs Folkert W, Castellani Gastone, Uh Hae-Won dec 2020, In: Scientific Reports. 10

All research output