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prof. dr. F.W. (Folkert) Asselbergs

prof. dr. F.W. (Folkert) Asselbergs

Full Professor
prof. dr. F.W. (Folkert) Asselbergs
  • Division of Heart & Lungs

Research Programs

Circulatory Health

Biography

Biography

Prof Dr. Folkert W. Asselbergs is Professor of Precision medicine at Institute of Health Informatics and the institute of Cardiovasculair Science, University College London, Director of the NIHR BRC UCL/UCLH Clinical and Research Informatics Unit, consultant cardiologist and Professor of Precision Medicine at University Medical Center Utrecht, University of Utrecht, the Netherlands, associate editor European Heart Journal, section digital health and innovation, Chair Center for Circulatory Health, UMC Utrecht, and chair data infrastructure Dutch Cardiovascular Alliance (www.dcvalliance.nl). 

 

Professor Asselbergs published more than 500 scientific papers in the field of cardiovascular disease and his work has been funded by the Netherlands Heart Foundation, Netherlands Heart Institute, British Heart Foundation, leDucq Foundation, EU FP7, European Society of Cardiology, BBMRI, National Institutes of Health, Innovative Medicines Initiative, European Research Area Network on Cardiovascular Diseases and ZonMw.

 

His research program in complex genetics focuses on the discovery of genes influencing susceptibility to cardiovascular disease; the application of these findings for the validation of drug targets; and the use of genetic tests for treatment targeting (stratified medicine). Lately, he widened his research focus to precision medicine using linked data sources such as wearable information and routine care data obtained from electronic health records including free text. His ambition is to build a network for performing clinical trials within routine health care linked to national registries. 

 

Prof Asselbergs is member of a large number of consortia and (co-) founded several consortia of which igenetrain (www.igenetrain.net), and GENIUS-CHD (www.genius-chd.org), and CAPACITY-COVID ( https://capacity-covid.eu)  are the most prominent and recent ones. He is scientific coordinator of European IMI Bigdate@heart consortium (www.bigdata-heart.eu). Bigdata@heart aims to deliver clinically relevant disease cardiovascular phenotypes, scalable insights from real-world evidence including data from registries, wearables and electronic health records, and insight driving drug development and personalized medicine through advanced big-data analytics. 

 

Side Activities

  • Prof of Precision medicine at the Institute of Cardiovascular Science and Institute of Health Informatics, University College London
  • Director NIHR BRC Clinical Research Informatics Unit, University College London Hospital
  • Chair Center for Circulatory Health, UMC Utrecht
  • Chair data infrastructure Dutch Cardiovascular Alliance (www.dcvalliane.nl)
  • Associate editor European Heart Journal, section Digital Health and Innovation

Fellowship and Awards

2003 Dr. E. Dekker Scholarship of the Dutch Heart Foundation (2003T010).
2005 Scholarship Netherlands Heart Institute for postdoc Harvard School of public health
2007 Netherlands Foundation of CardioVascular Excellence grant
2010 Clinical fellowship from the Netherlands Organisation for Health Research (ZonMw grant 90700342),
2012 European Society of Cardiology Training grant (T2012-006).
2013 Fellow European Society of Cardiology
2014 Dr. E. Dekker Scholarship of the Dutch Heart Foundation (2014T001)
2019 Scholarship European Society of Cardiology Executive Master Health Economics at LSE
2021 Pearl award ZonMw, Netherlands: www.zonmw.nl/nl/actueel/parelprojecten/parel-voorbruggenbouwer-in-hartfalen-onderzoek/

Research Output (468)

Genetic Basis of Dilated Cardiomyopathy in Dogs and Its Potential as a Bidirectional Model

Gaar-Humphreys Karen R, Spanjersberg Talitha C F, Santarelli Giorgia, Grinwis Guy C M, Szatmári Viktor, Roelen Bernard A J, Vink Aryan, van Tintelen J Peter, Asselbergs Folkert W, Fieten Hille, Harakalova Magdalena, van Steenbeek Frank G 1 Jul 2022, In: Animals : an open access journal from MDPI. 12 , p. 1-18

Electrocardiogram-based mortality prediction in patients with COVID-19 using machine learning

van de Leur R. R., Bleijendaal H., Taha K., Mast T., Gho J. M.I.H., Linschoten M., van Rees B., Henkens M. T.H.M., Heymans S., Sturkenboom N., Tio R. A., Offerhaus J. A., Bor W. L., Maarse M., Haerkens-Arends H. E., Kolk M. Z.H., van der Lingen A. C.J., Selder J. J., Wierda E. E., van Bergen P. F.M.M., Winter M. M., Zwinderman A. H., Doevendans P. A., van der Harst P., Pinto Y. M., Asselbergs F. W., van Es R., Tjong F. V.Y., Jun 2022, In: Netherlands Heart Journal. 30 , p. 312-318 7 p.

Automatic Identification of Patients With Unexplained Left Ventricular Hypertrophy in Electronic Health Record Data to Improve Targeted Treatment and Family Screening

Sammani Arjan, Jansen Mark, de Vries Nynke M, de Jonge Nicolaas, Baas Annette F, Te Riele Anneline S J M, Asselbergs Folkert W, Oerlemans Marish I F J 15 Apr 2022, In: Frontiers in cardiovascular medicine. 9 , p. 1-11

Unravelling the Difference Between Men and Women in Post-CABG Survival

Schmidt Amand F, Haitjema Saskia, Sartipy Ulrik, Holzmann Martin J, Malenka David J, Ross Cathy S, van Gilst Wiek, Rouleau Jean L, Meeder Annelijn M, Baker Robert A, Shiomi Hiroki, Kimura Takeshi, Tran Lavinia, Smith Julian A, Reid Christopher M, Asselbergs Folkert W, den Ruijter Hester M 13 Apr 2022, In: Frontiers in cardiovascular medicine. 9 , p. 1-7

Generation of human induced pluripotent stem cell (iPSC) lines derived from five patients carrying the pathogenic phospholamban-R14del (PLN-R14del) variant and three non-carrier family members

Mittal Nishka, Dave Jaydev, Harakalova Magdalena, van Tintelen J. Peter, Asselbergs Folkert W., Doevendans Pieter A., Costa Kevin D., Turnbull Irene C., Stillitano Francesca Apr 2022, In: Stem Cell Research. 60 , p. 1-5

Evaluation of the cardiac amyloidosis clinical pathway implementation:a real-world experience

Brons Maaike, Muller Steven A, Rutten Frans H, van der Meer Manon G, Vrancken Alexander F J E, Minnema Monique C, Baas Annette F, Asselbergs Folkert W, Oerlemans Marish I F J Mar 2022, In: European heart journal open. 2 , p. 1-9

Echocardiographic Deformation Imaging for Early Detection of Genetic Cardiomyopathies:JACC Review Topic of the Week

Taha Karim, Kirkels Feddo P., Teske Arco J., Asselbergs Folkert W., van Tintelen J. Peter, Doevendans Pieter A., Kutty Shelby, Haugaa Kristina H., Cramer Maarten J. 15 Feb 2022, In: Journal of the American College of Cardiology. 79 , p. 594-608 15 p.

Persistently elevated levels of sST2 after acute coronary syndrome are associated with recurrent cardiac events

van den Berg Victor J, Vroegindewey Maxime M, Umans Victor A, van der Harst Pim, Asselbergs Folkert W, Akkerhuis K Martijn, Kardys Isabella, Boersma Eric, 2 Feb 2022, In: Biomarkers. 27 , p. 264-269 6 p.

Reply to the Letter to the Editor: "It is urgent to evaluate the efficacy and safety of genotype guided antiplatelet therapy in patients after percutaneous coronary intervention in East Asian"

Al-Rubaish Abdullah M, Al-Muhanna Fahad A, Alshehri Abdullah M, Al-Mansori Mohammed A, Alali Rudaynah A, Khalil Rania M, Al-Faraidy Khalid A, Cyrus Cyril, Sulieman Mohammed M, Vatte Chittibabu, Loza Bao-Li, Claassens Daniel M F, Asselbergs Folkert W, Al-Ali Amein K 1 Feb 2022, In: International Journal of Cardiology. 348 , p. 57-57 1 p.

Less loop diuretic use in patients on sacubitril/valsartan undergoing remote pulmonary artery pressure monitoring

Böhm Michael, Assmus Birgit, Anker Stefan D, Asselbergs Folkert W, Brachmann Johannes, Brett Marie-Elena, Brugts Jasper J, Ertl Georg, Wang AiJia, Hilker Lutz, Koehler Friedrich, Rosenkranz Stephan, Leistner David M, Abdin Amr, Wintrich Jan, Zhou Qian, Adamson Philip B, Angermann Christiane E Feb 2022, In: ESC heart failure. 9 , p. 155-163 9 p.

All research output

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