Back

dr. M.L. (Marianne) Boes

dr. M.L. (Marianne) Boes

Associate Professor
dr. M.L. (Marianne) Boes
  • Medical Management

Biography

Biography

Marianne Boes heads the pediatric immunology laboratory at the UMC Utrecht, embedded in the Center for Translational Immunology. Her team focuses on approaches for harnessing the strength of the immune response and its promise to redirection using immune response modification, as preventive or therapeutic medicine. Boes trained in the USA in immunology and cell biology research (1996-2008). She performed PhD research at Massachusetts Institute of Technology (MIT), at the Koch Institute for integrative Cancer Research under supervision of prof. Jianzhu Chen. Here she studied immunodeficiency mechanisms using mouse models. Postdoctoral work she performed at Harvard Medical School in the laboratory of prof. Hidde Ploegh.

In 2004, Dr. Boes started her independent research lab at Brigham and Women’s Hospital/Harvard Medical School, financed in part by an NWO-Veni grant in 2004 and a large NIH-RO1 grant that was awarded to her.  She is the founding chair of the Young Academy of the UMC Utrecht (chair Sept 2019-Jan 2022) and board member of the CUCo working group of the Young Academies of the Strategic Alliance between TU-Eindhoven, Wageningen, Utrecht University and UMC-Utrecht, 2019-2022. Boes serves as coordinator of the course 'Advanced Immunology' and van Kinsbergen Advanced+ Immunology for PhD students. She is current member of the I&I graduate school teaching committee and the Board of Examiners, subcommittee Assessment Support Panel (ASP) @ GSLS-life Sciences Academy. She thoroughly enjoys to meet and learn from researchers, patients and societal partners in different fields. 

Side Activities

Scientific Advisory Board Member at Dutch Diabetes Research Foundation (Diabetes Fonds), June 2022-May 2026 (no payment)

Clinical Fellows program at ZonMw, vice-chair, 2019-current (< €1000)

IDSCOVA mRNA vaccination study LUMC (Establishing the tolerability, safety and immunogenicity of intradermal delivery of a mNRA SARS-CoV-2 vaccine in healthy adults), DSMB member, 2020-2021 (no payment)

Immunotherapy Advances (Oxford Academic Press), deputy-editor: 2019-current (< €1000)

Immunology Letters (Elsevier), section editor: 2022-current (< €1000)

 

Fellowship and Awards

 

Jan 2024 - Dec 2028: Horizon-HLTH CLARITY: 7 million euro/5 years (coordinator of consortium and PI)

2021-2023: EWUU-Unusual Collaboration grant; ±160K euro/yr (co-PI)

2022: PhD incentive Radboud University / UMC Utrecht, 270 KEuro (PI)

2021: Actuate grant 200K dollar (PI)

2019: Lymph&co 385K (PI)

2018: Nutricia 47.5K (co-PI)

2015: UU Life Sciences Seed grant 100K (co-PI)

2014: NWO-PhD grant 250K (I&I graduate school UU)

2014: Diabetes Fonds Nederland 250K (co-PI)

2010: ERC-Marie Curie 80K (PI)

2007: NIH-RO1 grant 750K (PI)

2004: NWO-Veni 250K (PI)

2001: Cancer Research Institute/ Irvington fellowship 300K (PI)

1997: Boehringer Ingelheim PhD fellowship 250K (PI)

 

 

 

 

 

 

 

 

 

 

 

Research Output (174)

Harnessing immunometabolism for cardiovascular health and cancer therapy

Markovska Angela, Schipper Henk, Boes Marianne 9 Nov 2021, In: Immunotherapy Advances. 1 , p. 1-3

A novel method to standardise serum IgA measurements shows an increased prevalence of IgA deficiency in young children with recurrent respiratory tract infections

Koenen Mischa, Bosma Marleen, Roorda Udo, Wopereis Fabienne, Roos Anja, van der Vries Erhard, Bogaert D, Sanders Elisabeth , Boes Marianne, Heidema Jojanneke, van Montfrans JM, Balemans Walter A F, van Holten Thijs C, Verhagen Lilly 29 Oct 2021, In: Clinical and Translational Immunology. 10 10 p.

Immunometabolic factors in adolescent chronic disease are associated with Th1 skewing of invariant Natural Killer T cells

Ververs Francesca, Engelen Suzanne, Nuboer Roos, Vastert SJ, van der Ent Kors , van 't Land Belinda, Garssen Johan, Monaco Claudia, Boes Marianne, Schipper Henk 11 Oct 2021, In: Scientific Reports. 11 11 p.

Role of Regulatory Cells in Immune Tolerance Induction in Hemophilia A

Schep Sarah, Schutgens Roger E, Fischer Kathelijn, Voorberg Jan, Boes Marianne May 2021, In: Hemasphere. 5 9 p.

Thrombotic Events in COVID-19 Are Associated With a Lower Use of Prophylactic Anticoagulation Before Hospitalization and Followed by Decreases in Platelet Reactivity

Clark Chantal C., Jukema Bernard N., Barendrecht Arjan D., Spanjaard Judith S., Jorritsma Nikita K.N., Smits Simone, de Maat Steven, Seinen Cor W., Verhoef Sandra, Parr Naomi M.J., Sebastian Silvie A.E., Koekman Arnold C., van Wesel Annet C.W., van Goor Harriet M.R., Spijkerman Roy, Bongers Suzanne H., van der Vries Erhard, Nierkens Stefan, Boes Marianne, Koenderman Leo, Kaasjager Karin A.H., Maas Coen, 22 Apr 2021, In: Frontiers in medicine. 8 , p. 1-11

Tissue-resident memory CD8+ T cells from skin differentiate psoriatic arthritis from psoriasis

Leijten Emmerik F, van Kempen Tessa S, Olde Nordkamp Michel A, Pouw Juliette N, Kleinrensink Nienke J, Vincken Nanette L, Mertens Jorre, Balak Deepak M W, Verhagen Fleurieke H, Hartgring Sarita A, Lubberts Erik, Tekstra Janneke, Pandit Aridaman, Radstake Timothy R, Boes Marianne 16 Jan 2021, In: Arthritis & Rheumatology. 73 , p. 1220-1232 13 p.

Upcoming immunotherapeutic combinations for B-cell lymphoma

Greve Patrick, Meyer Wentrup Friederike, Peperzak Victor, Boes Marianne 1 Jan 2021, In: Immunotherapy Advances. 1 14 p.

Revisiting B cell tolerance and autoantibodies in seropositive and seronegative autoimmune rheumatic disease (AIRD)

Pouw J N Juliëtte, Leijten E F A Emmerik, van Laar J M Jacob, Boes M Marianne 15 Nov 2020, In: Clinical and Experimental Immunology. 203 , p. 160-173 14 p.

CXCL4 Links Inflammation and Fibrosis by Reprogramming Monocyte-Derived Dendritic Cellsin vitro

Silva-Cardoso Sandra C., Tao Weiyang, Angiolilli Chiara, Lopes Ana P., Bekker Cornelis P. J., Devaprasad Abhinandan, Giovannone Barbara, van Laar Jaap, Cossu Marta, Marut Wioleta, Hack Erik, de Boer Rob J., Boes Marianne, Radstake Timothy R. D. J., Pandit Aridaman 17 Sep 2020, In: Frontiers in Immunology. 11

Broad proteomic screen reveals shared serum proteomic signature in patients with psoriatic arthritis and psoriasis without arthritis

Leijten Emmerik, Tao Weiyang, Pouw Juliette, van Kempen Tessa, Olde Nordkamp Michel, Balak Deepak, Tekstra J, Muñoz-Elías Ernesto, DePrimo Samuel, Drylewicz Julia, Pandit Aridaman, Boes Marianne, Radstake Timothy 13 Aug 2020, In: Rheumatology (Oxford, England). 60 , p. 751–761 11 p.

All research output

Thank you for your review!

Has this information helped you?

Please tell us why, so that we can improve our website.

Working at UMC Utrecht

Contact

Emergency?

Directions

Appointments

Practical

umcutrecht.nl uses cookies

This website uses cookies This website displays videos from, among others, YouTube. Such parties place cookies (third-party cookies). If you do not want these cookies, you can indicate that here. We also place cookies ourselves to improve our site.

Read more about the cookie policy

Agree No, rather not