Back

prof. dr. L.J. Bont

Full Professor

  • Laboratory for Translational Immunology (LTI)
  • Infectious Diseases
  • Infectious Diseases Research 2

prof. dr. L.J. Bont

Biography

Louis Bont is a Paediatrician Infectiologist at the Wilhelmina Children’s Hospital in the University Medical Center Utrecht, The Netherlands. He leads the Utrecht RSV Research Group. He is the coordinator of the Interest Group on Respiratory Infections of the European Society of Pediatric Infectious Diseases (ESPID) Research Committee. Dr. Bont is the founder and chairman of ReSViNET, an international RSV Research consortium. He has a strong interest in education of young talented researchers and founded the successful Training of Upcoming Leaders in Pediatric Science (TULIPS) career training program in the Netherlands. Dr. Bont served as advisor of the World Health Organization (WHO), the European Center of Disease Control (ECDC) and the Europarliament.

Louis Bont did his medical training at the Academic Medical Center in Amsterdam (1989-1996). He performed his PhD under the supervision of professor Jan Kimpen and professor Cobi Heijnen at the Wilhelmina Children’s Hospital (1997-2000). He was a post-doc at the Garofalo lab in Galveston, Texas (2000-2001). After returning to Utrecht, he followed the pediatric residency program followed by a pediatric infectious diseases and immunology fellowship. He have led the RSV Research Group since 2003 and became full professor in 2015.

The vision of his research is to combine clinical and basic research to decrease the global burden of RSV infection. The mission of his research group is to improve knowledge of RSV epidemiology, and to develop safe and effective therapeutic and preventive interventions.

In his work collaborate with patients is of highest importance. His work is supported by the RSV Patient Advisory Board (PAB) since 2012. The PAB has reviewed every grant application by the RSV Research Group. PAB members have been interviewed for newspapers and national television on RSV-related subjects.

Louis Bont actively participates as a teacher in the SUMMA program. In addition, he founded the TULIPS program in 2008 to train colleagues and young clinician-scientists.

Side Activities

  • Coordinator of the Interest Group on Respiratory Infections of the European Society of Pediatric Infectious Diseases (ESPID) Research Committee

    Chairman of ReSViNET, an international RSV Research Network.

    Advisor of the Europarliament

    Advisor of the World Health Organization for RSV-related programs

Fellowship and Awards

  • Full Professor (“Stimuleringshoogleraarschap”), expected in May 2015

    International Congress of Pediatric Pulmunology (CIPP) Award for Contribution to Understanding Childhood Respiratory Disease and Global Medical Education (2013)

    Dirkzwager-Assink Fonds Award by Catharijne Stichting for research on RSV bronchiolitis (2010)

    Ter Meulen Fonds lecture: It is not all asthma that wheezes. 27e Congres Nederlandse Vereniging voor Kindergeneeskunde, Veldhoven (2005)

    ESPID Fellowship Award 2001 Immunopathogenetic mechanisms of RSV infection in the mouse model (2001)

    Royal Dutch Academy of Science (Ter Meulen Fonds Stipendium). Immunopathogenetic mechanisms of RSV infection in the mouse model (2000)

Research Output (228)

Transcriptome of airway neutrophils reveals an interferon response in life-threatening respiratory syncytial virus infection

Besteman Sjanna B., Callaghan Amie, Langedijk Annefleur C., Hennus Marije P., Meyaard Linde, Mokry Michal, Bont Louis J., Calis Jorg J.A. nov 2020, In: Clinical Immunology. 220 , p. 108593

Global Molecular Epidemiology of Respiratory Syncytial Virus from the 2017-2018 INFORM-RSV Study

Tabor David E, Fernandes Fiona, Langedijk Annefleur C, Wilkins Deidre, Lebbink Robert Jan, Tovchigrechko Andrey, Ruzin Alexey, Kragten-Tabatabaie Leyla, Jin Hong, Esser Mark T, Bont Louis J, Abram Michael E, 21 okt 2020, In: Journal of Clinical Microbiology. 59

Defining asthma in children:how well do parents, doctors and spirometry agree?

Korsten Koos, Naaktgeboren Christiana A, Bont Louis J, van der Ent Cornelis K, de Hoog Marieke L A okt 2020, In: ERJ Open Research. 6

Comparison of illumina versus nanopore 16s rRNA gene sequencing of the human nasal microbiota

Heikema Astrid P., Horst-Kreft Deborah, Boers Stefan A., Jansen Rick, Hiltemann Saskia D., de Koning Willem, Kraaij Robert, de Ridder Maria A.J., van Houten Chantal B., Bont Louis J., Stubbs Andrew P., Hays John P. 21 sep 2020, In: Genes. 11 , p. 1-17 17 p.

Respiratory Syncytial Virus Consortium in Europe (RESCEU) Birth Cohort Study:Defining the Burden of Infant Respiratory Syncytial Virus Disease in Europe

Wildenbeest Joanne G, Zuurbier Roy P, Korsten Koos, van Houten Marlies A, Billard Marie N, Derksen-Lazet Nicole, Snape Matthew D, Drysdale Simon B, Robinson Hannah, Pollard Andrew J, Heikkinen Terho, Cunningham Steve, Leach Amanda, Martinón-Torres Federico, Rodríguez-Tenreiro Sánchez Carmen, Gómez-Carballa Alberto, Bont Louis J, 14 aug 2020, In: The Journal of infectious diseases. 222 , p. S606-S612

Presumed Risk Factors and Biomarkers for Severe Respiratory Syncytial Virus Disease and Related Sequelae:Protocol for an Observational Multicenter, Case-Control Study From the Respiratory Syncytial Virus Consortium in Europe (RESCEU)

Jefferies Kimberley, Drysdale Simon B, Robinson Hannah, Clutterbuck Elizabeth Ann, Blackwell Luke, McGinley Joseph, Lin Gu-Lung, Galal Ushma, Nair Harish, Aerssens Jeroen, Öner Deniz, Langedijk Annefleur, Bont Louis, Wildenbeest Joanne G, Martinon-Torres Federico, Rodríguez-Tenreiro Sánchez Carmen, Nadel Simon, Openshaw Peter, Thwaites Ryan, Widjojoatmodjo Myra, Zhang Linong, Nguyen Thi Lien-Anh, Giaquinto Carlo, Giordano Giuseppe, Baraldi Eugenio, Pollard Andrew J, 14 aug 2020, In: The Journal of infectious diseases. 222 , p. S658-S665

Assessing the strength of evidence for a causal effect of respiratory syncytial virus lower respiratory tract infections on subsequent wheezing illness:a systematic review and meta-analysis

Brunwasser Steven M, Snyder Brittney M, Driscoll Amanda J, Fell Deshayne B, Savitz David A, Feikin Daniel R, Skidmore Becky, Bhat Niranjan, Bont Louis J, Dupont William D, Wu Pingsheng, Gebretsadik Tebeb, Holt Patrick G, Zar Heather J, Ortiz Justin R, Hartert Tina V aug 2020, In: The Lancet Respiratory Medicine. 8 , p. 795-806 12 p.

Global molecular diversity of RSV - the "INFORM RSV" study

Langedijk Annefleur C, Lebbink Robert Jan, Naaktgeboren Christiana, Evers Anouk, Viveen Marco C, Greenough Anne, Heikkinen Terho, Stein Renato T, Richmond Peter, Martinón-Torres Federico, Nunes Marta, Hosoya Mitsuaki, Keller Christian, Bauck Monika, Cohen Robert, Papenburg Jesse, Pernica Jeffrey, Hennus Marije P, Jin Hong, Tabor David E, Tovchigrechko Andrev, Ruzin Alexey, Abram Michael E, Wilkins Deidre, Wildenbeest Joanne G, Kragten-Tabatabaie Leyla, Coenjaerts Frank E J, Esser Mark T, Bont Louis J 26 jun 2020, In: BMC Infectious Diseases. 20

Low Sensitivity of BinaxNOW RSV in Infants

Zuurbier Roy P, Bont Louis J, Langedijk Annefleur C, Hamer Mirjam, Korsten Koos, Drysdale Simon B, Snape Matthew D, Robinson Hannah, Pollard Andrew J, Martinón-Torres Federico, Rodríguez-Tenreiro Sánchez Carmen, Gómez-Carballa Alberto, Dacosta-Urbieta Ana Isabel, Heikkinen Terho, Cunningham Steve, van Houten Marlies A, Wildenbeest Joanne G, 30 mrt 2020, In: The Journal of infectious diseases. 222 , p. S640-S647

Infant respiratory syncytial virus prophylaxis and nasopharyngeal microbiota until 6 years of life:a subanalysis of the MAKI randomised controlled trial

Man Wing Ho, Scheltema Nienke M, Clerc Melanie, van Houten Marlies A, Nibbelke Elisabeth E, Achten Niek B, Arp Kayleigh, Sanders Elisabeth A M, Bont Louis J, Bogaert Debby 20 mrt 2020, In: The Lancet Respiratory Medicine. 8 , p. 1022-1031 10 p.

All Research Output (228)