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dr. R.M. (Rachel) Brouwer Assistant Professor

  • Psychiatry


Research Programs


Rachel Brouwer obtained her PhD in the field of mathematics under supervision of Prof. J. van den Berg, at the Center of Mathematics and Computer Science in 2005. The title of her PhD was “Percolation, forest-fires and monomer-dimers, or the hunt for self-organized criticality”.

Since april 2006, she is working in the Department of Psychiatry of the University Medical Center Utrecht, were she is senior researcher on the BrainSCALE project, a longitudinal twin study into healthy development of brain and cognition during puberty, and the genetic and environmental components that influence this development. She is involved in the twin studies of the department, and in development of post-processing of MRI data and its statistical analysis.

Research lines

BrainSCALE project; a longitudinal twin-sibling study in adolescence into brain and cognition

ENIGMA-plasticity; through the ENIGMA consortium we investigate the genetics of brain plasticity measured through longitudinal MRI

Selected publications

Rachel M Brouwer, Matthew S Panizzon, David C Glahn, Derrek P Hibar, Xue Hua, Neda Jahanshad, Lucija Abramovic, Greig I de Zubicaray, Carol E Franz, Narelle K Hansell, Ian B Hickie, Marinka M G Koenis, Nicholas G Martin, Karen A Mather, Katie L McMahon, Hugo G Schnack, Lachlan T Strike, Suzanne C Swagerman, Anbupalam Thalamuthu, Wei Wen & 9 others, 2017, Genetic influences on individual differences in longitudinal changes in global and subcortical brain volumes: Results of the ENIGMA plasticity working group. Human brain mapping DOI.

Bohlken, M. M., Brouwer, R. M., Mandl, R. C. W., Kahn, R. S. & Hulshoff Pol, H. E. (2016) Genetic Variation in Schizophrenia Liability is Shared With Intellectual Ability and Brain Structure. Schizophrenia Bulletin. 425p. 1167-1175

Brouwer, R. M., Hedman, A. M., van Haren, N. E. M., Schnack, H. G., Brans, R. G. H., Smit, D. J., Kahn, R. S., Boomsma, D. I. & Hulshoff Pol, H. E. (2014) Heritability of brain volume change and its relation to intelligence. Neuroimage. 100p. 676-683 8 p.

van Soelen IL, Brouwer RM, van Baal GC, Schnack HG, Peper JS, Chen L, Kahn RS, Boomsma DI, Pol HE (2013): Heritability of volumetric brain changes and height in children entering puberty. Hum Brain Map Mar;34(3):713-25.


Research Output (28)

Genetic and environmental influences on functional connectivity within and between canonical cortical resting-state networks throughout adolescent development in boys and girls

Teeuw Jalmar, Brouwer Rachel M, Guimarães João P O F T, Brandner Philip, Koenis Marinka M G, Swagerman Suzanne C, Verwoert Maxime, Boomsma Dorret I, Hulshoff Pol Hilleke E 3 aug 2019, In: NeuroImage. 202 16 p.

Community housing: functional outcome of severe mental illness is associated with the personality traits of the case manager

Lodder Mandy, Schrijvers A. J. P., de Leeuw J. R. J., Brouwer R. M., Cahn W. 3 jun 2019, In: HOUSING CARE AND SUPPORT. 22 , p. 106-113 8 p.

ENIGMA-Relatives: The Association Between Familial Risk for Schizophrenia or Bipolar Disorder and Brain Abnormalities

de Zwarte Sonja, Brouwer Rachel, Ching Christopher, Andreassen Ole, van Erp Theo, Turner Jessica, Thompson Paul, Kahn Rene, van Haren Neeltje 15 mei 2019, In: Biological Psychiatry. 85 , p. S8-S9


Lemvigh Cecilie, Brouwer Rachel, Pantelis Christos, Hilker Rikke, Robbins Trevor W., Sahakian Barbara, Glenthoj Birte, Fagerlund Birgitte apr 2019, In: Schizophrenia Bulletin. 45 , p. S171-S171

Heritability of Cerebral Blood Flow and the Correlation to Schizophrenia Spectrum Disorders:A Pseudo-continuous Arterial Spin Labeling Twin Study

Legind Christian S, Broberg Brian V, Brouwer Rachel, Mandl René C W, Ebdrup Bjørn H, Anhøj Simon J, Jensen Maria H, Hilker Rikke, Fagerlund Birgitte, Hulshoff Pol Hilleke E, Glenthøj Birte Y, Rostrup Egill 18 feb 2019, In: Schizophrenia Bulletin. 45 , p. 1231-1241 11 p.

Genetic and environmental influences on circulating NK and T cells and their relation to bipolar disorder

Snijders G, Brouwer R, Kemner S, Bootsman F, Drexhage H A, Hillegers M H J 10 feb 2019, In: International journal of bipolar disorders. 7

Homogenizing Estimates of Heritability Among SOLAR-Eclipse, OpenMx, APACE, and FPHI Software Packages in Neuroimaging Data

Kochunov Peter, Patel Binish, Ganjgahi Habib, Donohue Brian, Ryan Meghann, Hong Elliot L., Chen Xu, Adhikari Bhim, Jahanshad Neda, Thompson Paul M., Van’t Ent Dennis, den Braber Anouk, de Geus Eco J.C., Brouwer Rachel M., Boomsma Dorret I., Hulshoff Pol Hilleke E., de Zubicaray Greig I., McMahon Katie L., Martin Nicholas G., Wright Margaret J., Nichols Thomas E. 7 feb 2019, In: Frontiers in Neuroinformatics [E]. 13

Running in the Family?:Structural Brain Abnormalities and IQ in Offspring, Siblings, Parents, and Co-twins of Patients with Schizophrenia

De Zwarte Sonja M.C., Brouwer Rachel M., Tsouli Andromachi, Cahn Wiepke, Hillegers Manon H.J., Hulshoff Pol Hilleke E., Kahn René S., Van Haren Neeltje E.M. 28 dec 2018, In: Schizophrenia Bulletin. 45 , p. 1209-1217 9 p.

Erratum to:Associations between subjective well-being and subcortical brain volumes (Scientific Reports, (2017), 7, 1, (6957), 10.1038/s41598-017-07120-z)

van ’t Ent D., den Braber A., Baselmans B. M.L., Brouwer R. M., Dolan C. V., Pol H. E.Hulshoff, de Geus E. J.C., Bartels M. 1 dec 2018, In: Scientific Reports. 8

Auditory hallucinations in adults with hearing impairment:a large prevalence study

Linszen M. M.J., van Zanten G. A., Teunisse R. J., Brouwer R. M., Scheltens P., Sommer I. E. 20 mrt 2018, In: Psychological Medicine. 49 , p. 132-139 8 p.

All Research Output (28)
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