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prof. dr. W. (Wiepke) Cahn

Full Professor

  • Psychiatry

prof. dr. W. (Wiepke) Cahn

Research Programs

Biography

Prof. Wiepke Cahn has been a research psychiatrist at the University Medical Center Utrecht since 1996. In 2003 she obtained her PhD titled ‘brain morphology during the early course of schizophrenia’. She has set up various (multicenter) research projects, including GROUP. She has been chief psychiatrist for the schizophrenia program at the UMCUtrecht and project manager for the Utrecht Youth Cohort. Currently she is heading the ‘body & life’ clinic at the department of psychiatry. In 2016 she was appointed professor of psychiatry. Her research interest is the physical (ill-)health in psychiatric disorders.

Wiepke Cahn is vice-president of the Dutch Psychiatric Association. She has authored more than 200 papers and book chapters and has been chief editor of ‘handboek schizofrenie’. Her non-research-based activities consist of treating patients and their families with psychotic and bipolar disorders.

Research Line

Physical health in psychiatric disorders

Most recent key publications

  1. Liemburg EJ, Bruins J, van Beveren N, Islam MA, Alizadeh BZ; GROUP investigators. Cannabis and a lower BMI in psychosis: What is the role of AKT1? Schizophr Res. 2016 Oct;176(2-3):95-9.
  2. de Nijs J, Pet MA; GROUP Investigators.. Metabolic syndrome in schizophrenia patients associated with poor premorbid school performance in early adolescence. Acta Psychiatr Scand. 2016 Apr;133(4):289-97.
  3. Scheewe TW, Backx FJ, Takken T, Jörg F, van Strater AC, Kroes AG, Kahn RS, Cahn W. Exercise therapy improves mental and physical health in schizophrenia: a randomised controlled trial. Acta Psychiatr Scand. 2013 Jun;127(6):464-73.
  4. Welie H, Derks EM, Verweij KH, de Valk HW, Kahn RS, Cahn W. The prevalence of diabetes mellitus is increased in relatives of patients with a non-affective psychotic disorder. Schizophr Res. 2013 Feb;143(2-3):354-7.
  5. Cahn W, Ramlal D, Bruggeman R, de Haan L, Scheepers FE, van Soest MM, Assies J, Slooff CJ. [Prevention and treatment of somatic complications arising from the use of antipsychotics]. Tijdschr Psychiatr. 2008;50(9):579-91.

 

Side Activities

  • GGz Breburg Supervisory Board

    Full Professor, Altrecht Science

Fellowship and Awards

    • Genetic Risk and Outcome of Psychosis (GROUP project) – i.s.m. AMC, UMCG en Universiteit van Maastricht
    • Topfit project – i.s.m. met sportgeneeskunde
    • GRUMPY or Depressed – i.s.m. de sociale faculteit UU
    • Adding in- and outpatient parmacotherapeutic treatment information – i.s.m. de faculteit farmaceutische wetenschappen
    • International panel study on the appropriate pharmacological management of early schizophrenia – RAND/UCLA study

Research Output (281)

Neutrophil fluorescence in clozapine users is attributable to a 14kDa secretable protein

de With Sera A.J., Man Wai H., Maas Coen, Ten Berg Maarten, Cahn Wiepke, Koekman Arnold C., van Solinge Wouter W., Tak Tamar 1 okt 2020, In: Pharmacology research & perspectives. 8 , p. e00627

Functional brain networks in the schizophrenia spectrum and bipolar disorder with psychosis

van Dellen Edwin, Börner Corinna, Schutte Maya, van Montfort Simone, Abramovic Lucija, Boks Marco P., Cahn Wiepke, van Haren Neeltje, Mandl René, Stam Cornelis J., Sommer Iris 2 sep 2020, In: npj Schizophrenia. 6

Polygenic risk score for schizophrenia was not associated with glycemic level (HbA1c) in patients with non-affective psychosis:Genetic Risk and Outcome of Psychosis (GROUP) cohort study

Habtewold Tesfa Dejenie, Islam Md Atiqul, Liemburg Edith J., Bartels-Velthuis Agna A.A., van Beveren Nico J., Cahn Wiepke, de Haan Lieuwe, Delespaul Philippe, Meijer Carin J., Myin-Germeys Inez, Kahn Rene S., Schirmbeck Frederike, Simons Claudia J.P., van Amelsvoort Therese, van Haren Neeltje E., van Os Jim, van Winkel Ruud, Bruggeman Richard, Alizadeh Behrooz Z., 1 mei 2020, In: Journal of Psychosomatic Research. 132

The genetic architecture of the human cerebral cortex

Grasby Katrina L, Jahanshad Neda, Painter Jodie N, Colodro-Conde Lucía, Bralten Janita, Hibar Derrek P, Lind Penelope A, Pizzagalli Fabrizio, Ching Christopher R K, McMahon Mary Agnes B, Shatokhina Natalia, Zsembik Leo C P, Thomopoulos Sophia I, Zhu Alyssa H, Strike Lachlan T, Agartz Ingrid, Alhusaini Saud, Almeida Marcio A A, Alnæs Dag, Amlien Inge K, Andersson Micael, Ard Tyler, Armstrong Nicola J, Ashley-Koch Allison, Atkins Joshua R, Bernard Manon, Brouwer Rachel M, Buimer Elizabeth E L, Bülow Robin, Bürger Christian, Cannon Dara M, Chakravarty Mallar, Chen Qiang, Cheung Joshua W, Couvy-Duchesne Baptiste, Dale Anders M, Dalvie Shareefa, de Araujo Tânia K, de Zubicaray Greig I, de Zwarte Sonja M C, Klein Marieke, van Haren Neeltje E M, Veldink Jan H, Ayesa-Arriola Rosa, Cahn Wiepke, Hillegers Manon H J, Hulshoff Pol Hilleke E, Kahn René S, Ophoff Roel A, Sommer Iris E, 20 mrt 2020, In: Science. 367 , p. 1340-+

Using machine learning to predict mental healthcare consumption in non-affective psychosis

Kwakernaak Sascha, van Mens Kasper, Cahn Wiepke, Janssen Richard, 5 mrt 2020, In: Schizophrenia Research. 218 , p. 166-172 7 p.

Cognition and violent behavior in psychotic disorders:A nationwide case-control study

Lamsma Jelle, Cahn Wiepke, Fazel Seena, mrt 2020, In: Schizophrenia Research: Cognition. 19

De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia

Rees Elliott, Han Jun, Morgan Joanne, Carrera Noa, Escott-Price Valentina, Pocklington Andrew J., Duffield Madeleine, Hall Lynsey S., Legge Sophie E., Pardiñas Antonio F., Richards Alexander L., Roth Julian, Lezheiko Tatyana, Kondratyev Nikolay, Kaleda Vasilii, Golimbet Vera, Parellada Mara, González-Peñas Javier, Arango Celso, Alizadeh Behrooz Z., van Amelsvoort Therese, Bruggeman Richard, Cahn Wiepke, de Haan Lieuwe, Luykx Jurjen J., Rutten Bart P.F., van Os Jim, van Winkel Ruud, Gawlik Micha, Kirov George, Walters James T.R., Holmans Peter, O’Donovan Michael C., Owen Michael J., 1 feb 2020, In: Nature Neuroscience. 23 , p. 179-184 6 p.

Aggressive Behavior, Hostility, and Associated Care Needs in Patients With Psychotic Disorders:A 6-Year Follow-Up Study

Faay Margo D. M., van Os Jim, van Amelsvoort Therese, Bartels-Velthuis Agna A., Bruggeman Richard, Cahn Wiepke, de Haan Lieuwe, Schirmbeck Frederike, Simons Claudia J. P., 8 jan 2020, In: Frontiers in Psychiatry. 10 , p. 934

Childhood trauma and coping in patients with psychotic disorders and obsessive-compulsive symptoms and in un-affected siblings

Renkema Tristan C., de Haan Lieuwe, Schirmbeck Frederike, Alizadeh Behrooz Z., van Amelsvoort Therese, Bartels-Velthuis Agna A., van Beveren Nico J., Bruggeman Richard, Cahn Wiepke, Delespaul Philippe, Luykx Jurjen J., Myin-Germeys Inez, Kahn Rene S., Simons Claudia J.P., van Os Jim, van Winkel Ruud, jan 2020, In: Child Abuse and Neglect. 99

Course of covid-19 infections and impact on mental health; setting up a national case register

Van Helvoort Marloes, Van Dee Violet, Dirks Astrid, Everaerd Daphne, Metz Margot, Van Schijndel Maarten, Tendolkar Indira, Zinkstok Janneke, Cahn Wiepke, Schellekens Arnt 2020, In: Tijdschrift voor Psychiatrie. 62 , p. 739-742 4 p.

All Research Output (281)