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dr. O.L. (Olaf) Cremer Associate Professor

  • Intensive Care Medicine

Research programs

Biography

Olaf Cremer (1971) was trained as an anesthesiologist, intensivist and clinical epidemiologist. He has worked as a full-time staff member in the department of intensive care medicine of the UMCU since 2007. Dr. Cremer has designed and co-developed the patient data management system that is currently in use. His detailed knowledge of the system and computer programming skills allow him to explore this clinical database as a rich source of information for several research projects within the division.
Dr. Cremer obtained his PhD degree in 2005 with a doctoral thesis on goal-directed management of patients with severe traumatic brain injury. His thesis included both experimental clinical studies focused on cerebrovascular pathophysiology, as well as large cohort studies focused on patient outcomes. Since 2008 he has been studying the clinical epidemiology of infections in the ICU. To this aim, dr. Cremer is the clinical PI of the MARS (Molecular Diagnosis and Risk Stratification in Sepsis) study, an ongoing multicenter project aiming to develop and validate new technologies for early diagnosis and prognostication in sepsis. Within this study framework, he focuses on the modeling of outcomes and complications of severe sepsis with adjustment for competing risks and time-dependent covariates. He currently is (or has been) mentoring 7 PhD students.

Research Output

Iron metabolism in critically ill patients developing anemia of inflammation: a case control study

Boshuizen Margit, Binnekade Jan M., Nota Benjamin, van de Groep K, Cremer OL, Tuinman Pieter R., Horn Janneke, Schultz Marcus J., van Bruggen Robin, Juffermans Nicole P., de Beer Friso M., Bos Lieuwe D.J., Glas Gerie J., van Hooijdonk Roosmarijn T.M., Schouten Laura R.A., Straat Marleen, Witteveen Esther, Wieske Luuk, Hoogendijk Arie J., Huson Mischa A., Scicluna Brendon P., van der Poll Tom, van Vught Lonneke A., Wiewel Maryse A., Bonten MJM, Frencken JF, Klein Klouwenberg PMC, Brouwer ME, Ong DSY, Verboom DM, 1 Dec 2018 In: Annals of Intensive Care. 8 8 p.

Molecular Biomarker to Assist in Diagnosing Abdominal Sepsis upon ICU Admission

Scicluna Brendon P, Wiewel Maryse A, Van Vught Lonneke A., Hoogendijk Arie J, Klarenbeek Augustijn M, Franitza Marek, Toliat Mohammad R, Nürnberg Peter, Horn Janneke, Bonten MJM, Schultz Marcus J., Cremer OL, Van Der Poll Tom Apr 2018 In: American Journal of Respiratory and Critical Care Medicine. 197, p. 1070-1073

The ability of intensive care unit physicians to estimate long-term prognosis in survivors of critical illness

Soliman IW, Cremer OL, de Lange DW, Slooter AJC, van Delden JJM, van Dijk D, Peelen LM 1 Feb 2018 In: Journal of Critical Care. 43, p. 148-155 8 p.

Myocardial Injury in Patients with Sepsis and Its Association with Long-Term Outcome

Frencken JF, Donker DW, Spitoni C, Brouwer ME, Soliman IW, Ong DSY, Horn Janneke, Van Der Poll Tom, van Klei WA, Bonten MJM, Cremer OL 1 Feb 2018 In: Circulation. Cardiovascular Quality and Outcomes. 11

The host response in critically ill sepsis patients on statin therapy: a prospective observational study

Wiewel Maryse A, Scicluna Brendon P, Van Vught Lonneke A., Hoogendijk Arie J, Zwinderman Aeilko H, Lutter René, Horn Janneke, Cremer OL, Bonten MJM, Schultz Marcus J., Van Der Poll Tom 18 Jan 2018 In: Annals of Intensive Care. 8 12 p.

Reply to Lipcsey

Ong DSY, Bonten MJM, Cremer OL 18 Jan 2018 In: Clinical Infectious Diseases. 66, p. 482

Development and Validation of an Abbreviated Questionnaire to Easily Measure Cognitive Failure in ICU Survivors: A Multicenter Study

Wassenaar Annelies, de Reus Jorn, Donders A Rogier T, Schoonhoven Lisette, Cremer OL, de Lange DW, van Dijk D, Slooter AJC, Pickkers Peter, Van Den Boogaard Mark 1 Jan 2018 In: Critical Care Medicine. 46, p. 79-84 6 p.

Respiratory Viruses in Invasively Ventilated Critically Ill Patients-A Prospective Multicenter Observational Study

van Someren Gréve Frank, Juffermans Nicole P, Bos Lieuwe D J, Binnekade Jan M, Braber Annemarije, Cremer OL, de Jonge Evert, Molenkamp Richard, Ong DSY, Rebers Sjoerd P H, Spoelstra-de Man Angelique M E, van der Sluijs Koenraad F, Spronk Peter E, Verheul Kirsten D, de Waard Monique C, de Wilde Rob B P, Winters Tineke, de Jong Menno D, Schultz Marcus J. Jan 2018 In: Critical Care Medicine. 46, p. 29 36 p.

Macrolide therapy is associated with reduced mortality in acute respiratory distress syndrome (ARDS) patients

Simonis Fabienne D., de Iudicibus Gianfranco, Cremer OL, Ong DSY, van der Poll Tom, Bos Lieuwe D., Schultz Marcus J. Jan 2018 In: Annals of Translational Medicine. 6 9 p.

The Times They Are A-Changin': Time-Dependent Exposures and Time-Dependent Confounders

Frencken JF, Postma DF, van Werkhoven CH, Cremer OL, Bonten MJM 1 Dec 2017 In: Clinical Infectious Diseases. 65, p. 1959-1960

Universitair Medisch Centrum Utrecht © 2018 Universitair Medisch Centrum Utrecht

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