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dr. O.L. (Olaf) Cremer Assistant Professor - medical

  • Intensive Care Medicine

Research programs

Biography

Olaf Cremer (1971) was trained as an anesthesiologist, intensivist and clinical epidemiologist. He has worked as a full-time staff member in the department of intensive care medicine of the UMCU since 2007. Dr. Cremer has designed and co-developed the patient data management system that is currently in use. His detailed knowledge of the system and computer programming skills allow him to explore this clinical database as a rich source of information for several research projects within the division.
Dr. Cremer obtained his PhD degree in 2005 with a doctoral thesis on goal-directed management of patients with severe traumatic brain injury. His thesis included both experimental clinical studies focused on cerebrovascular pathophysiology, as well as large cohort studies focused on patient outcomes. Since 2008 he has been studying the clinical epidemiology of infections in the ICU. To this aim, dr. Cremer is the clinical PI of the MARS (Molecular Diagnosis and Risk Stratification in Sepsis) study, an ongoing multicenter project aiming to develop and validate new technologies for early diagnosis and prognostication in sepsis. Within this study framework, he focuses on the modeling of outcomes and complications of severe sepsis with adjustment for competing risks and time-dependent covariates. He currently is (or has been) mentoring 9 PhD students.

Research Output

Perioperative challenges during surgical evacuation of subdural and epidural hematomas.

van den Bergh Walter M., Absalom Anthony R., Cremer OL 19 Sep 2019

Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis

van de Groep Kirsten, Bos Martine P, Varkila Meri R J, Savelkoul Paul H M, Ong David S Y, Derde Lennie P G, Juffermans Nicole P, van der Poll Tom, Bonten Marc J M, Cremer Olaf L 26 Jun 2019 In: European Journal of Clinical Microbiology & Infectious Diseases.

Matrix metalloproteinase-8: a useful biomarker to refine the diagnosis of community-acquired pneumonia upon intensive care unit admission?

Uhel Fabrice, Scicluna Brendon P, van Vught Lonneke A, Cremer Olaf L, Bonten Marc J, Schultz Marcus J, van der Poll Tom 20 Jun 2019 In: Critical care (London, England). 23

Adjusting for Disease Severity Across ICUs in Multicenter Studies

Brakenhoff Timo B, Plantinga Nienke L, Wittekamp Bastiaan H J, Cremer Olaf, de Lange Dylan W, de Keizer Nicolet F, Bakhshi-Raiez Ferishta, Groenwold Rolf H H, Peelen Linda M 24 May 2019 In: Critical Care Medicine.

Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study

Schouten Laura R., van Kaam Anton H., Kohse Franziska, Veltkamp Floor, Bos Lieuwe D., de Beer Friso M., van Hooijdonk Roosmarijn T., Horn Janneke, Straat Marleen, Witteveen Esther, Glas Gerie J., Wieske Luuk, van Vught Lonneke A., Wiewel Maryse A., Ngelse Sarah A., I, Cortjens Bart, van Woensel Job B., Bos Albert P., Walther Thomas, Schultz Marcus J., Wosten-van Asperenl Roelie M., Hoogendijk Arie J., Huson Mischa A., van der Poll Tom, Scicluna Brendon, Bonten Marc J., Cremer Olaf L., Frencken Jos F., van de Groep Kirsten, Klouwenberg Peter M. Klein, Koster-Brouwer Maria E., Ong David S., Verboom Diana M. 14 May 2019 In: Annals of Intensive Care. 9

Detection of Invasive Aspergillosis in Critically Ill Patients with Influenza: the Role of Plasma Galactomannan

van de Groep Kirsten, Verboom Diana M, van de Veerdonk Frank L, Haas Pieter-Jan A, van der Poll Tom, Schultz Marcus J, Bonten Marc J M, Cremer Olaf L 1 May 2019 In: American Journal of Respiratory and Critical Care Medicine.

Epidemiology and outcomes of source control procedures in critically ill patients with intra-abdominal infection

van de Groep Kirsten, Verhoeff Tessa L, Verboom Diana M, Bos Lieuwe D, Schultz Marcus J, Bonten Marc J M, Cremer Olaf L 12 Mar 2019 In: Journal of Critical Care.

Determinants of self-reported unacceptable outcome of intensive care treatment 1year after discharge

Kerckhoffs Monika C., Kosasi Felicia F. L., Soliman Ivo W., van Delden Johannes J. M., Cremer Olaf L., de Lange Dylan W., Slooter Arjen J. C., Kesecioglu Jozef, van Dijk Diederik 6 Mar 2019 In: Intensive Care Medicine. 45, p. 806-814 9 p.

Understanding Heterogeneity in Biological Phenotypes of ARDS by Leukocyte Expression Profiles

Bos Lieuwe Dj, Scicluna Brendon P, Ong David Y, Cremer Olaf, van der Poll Tom, Schultz Marcus J 15 Jan 2019 In: American Journal of Respiratory and Critical Care Medicine.

Profile of the SeptiCyte™ LAB gene expression assay to diagnose infection in critically ill patients

Verboom D M, Koster-Brouwer M E, Varkila Mrj, Bonten Mjm, Cremer O L 9 Jan 2019 In: Expert Review of Molecular Diagnostics.

© 2019  

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