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dr. O.L. (Olaf) Cremer Assistant Professor - medical

  • Intensive Care Medicine

Research programs

Biography

Olaf Cremer (1971) was trained as an anesthesiologist, intensivist and clinical epidemiologist. He has worked as a full-time staff member in the department of intensive care medicine of the UMCU since 2007. Dr. Cremer has designed and co-developed the patient data management system that is currently in use. His detailed knowledge of the system and computer programming skills allow him to explore this clinical database as a rich source of information for several research projects within the division.
Dr. Cremer obtained his PhD degree in 2005 with a doctoral thesis on goal-directed management of patients with severe traumatic brain injury. His thesis included both experimental clinical studies focused on cerebrovascular pathophysiology, as well as large cohort studies focused on patient outcomes. Since 2008 he has been studying the clinical epidemiology of infections in the ICU. To this aim, dr. Cremer is the clinical PI of the MARS (Molecular Diagnosis and Risk Stratification in Sepsis) study, an ongoing multicenter project aiming to develop and validate new technologies for early diagnosis and prognostication in sepsis. Within this study framework, he focuses on the modeling of outcomes and complications of severe sepsis with adjustment for competing risks and time-dependent covariates. He currently is (or has been) mentoring 9 PhD students.

Research Output

Perioperative challenges during surgical evacuation of subdural and epidural hematomas.

van den Bergh Walter M., Absalom Anthony R., Cremer OL 19 Sep 2019

Detection of Invasive Aspergillosis in Critically Ill Patients with Influenza: the Role of Plasma Galactomannan

van de Groep Kirsten, Verboom Diana M, van de Veerdonk Frank L, Haas Pieter-Jan A, van der Poll Tom, Schultz Marcus J, Bonten Marc J M, Cremer Olaf L 1 May 2019 In: American Journal of Respiratory and Critical Care Medicine.

Epidemiology and outcomes of source control procedures in critically ill patients with intra-abdominal infection

van de Groep Kirsten, Verhoeff Tessa L, Verboom Diana M, Bos Lieuwe D, Schultz Marcus J, Bonten Marc J M, Cremer Olaf L 12 Mar 2019 In: Journal of Critical Care.

Determinants of self-reported unacceptable outcome of intensive care treatment 1year after discharge

Kerckhoffs Monika C., Kosasi Felicia F. L., Soliman Ivo W., van Delden Johannes J. M., Cremer Olaf L., de Lange Dylan W., Slooter Arjen J. C., Kesecioglu Jozef, van Dijk Diederik 6 Mar 2019 In: Intensive Care Medicine. 45, p. 806-814

Understanding Heterogeneity in Biological Phenotypes of ARDS by Leukocyte Expression Profiles

Bos Lieuwe Dj, Scicluna Brendon P, Ong David Y, Cremer Olaf, van der Poll Tom, Schultz Marcus J 15 Jan 2019 In: American Journal of Respiratory and Critical Care Medicine.

Profile of the SeptiCyte™ LAB gene expression assay to diagnose infection in critically ill patients

Verboom D M, Koster-Brouwer M E, Varkila Mrj, Bonten Mjm, Cremer O L 9 Jan 2019 In: Expert Review of Molecular Diagnostics.

Rationalizing antimicrobial therapy in the ICU: a narrative review

Timsit Jean François, Bassetti Matteo, Cremer Olaf, Daikos George, de Waele Jan, Kallil Andre, Kipnis Eric, Kollef Marin, Laupland Kevin, Paiva Jose Artur, Rodríguez-Baño Jesús, Ruppé Étienne, Salluh Jorge, Taccone Fabio Silvio, Weiss Emmanuel, Barbier François 1 Jan 2019 In: Intensive Care Medicine.

Is research from databases reliable?: Not sure

Varkila Meri R J, Cremer Olaf L Jan 2019 In: Intensive Care Medicine. 45, p. 122-124 3 p.

Effect of cytomegalovirus reactivation on the time course of systemic host response biomarkers in previously immunocompetent critically ill patients with sepsis: A matched cohort study

Van De Groep K., Nierkens Stefan, Cremer Olaf L., Peelen Linda M., Klein Klouwenberg Peter M.C., Schultz Marcus J., Hack C. Erik, Van Der Poll Tom, Bonten Marc J.M., Ong David S.Y., De Beer Friso M., Bos Lieuwe D.J., Glas Gerie J., Hoogendijk Arie J., Van Hooijdonk Roosmarijn T.M., Horn Janneke, Huson Mischa A., Juffermans Nicole P., Schouten Laura R.A., Scicluna Brendon, Straat Marleen, Van Vught Lonneke A., Wieske Luuk, Wiewel Maryse A., Witteveen Esther, Frencken Jos F., Van De Groep K., Koster-Brouwer Maria E., Varkila Meri R.J., Verboom Diana M. 18 Dec 2018 In: Critical Care. 22

Iron metabolism in critically ill patients developing anemia of inflammation: a case control study

Boshuizen Margit, Binnekade Jan M., Nota Benjamin, van de Groep Kirsten, Cremer Olaf L., Tuinman Pieter R., Horn Janneke, Schultz Marcus J., van Bruggen Robin, Juffermans Nicole P., de Beer Friso M., Bos Lieuwe D.J., Glas Gerie J., van Hooijdonk Roosmarijn T.M., Schouten Laura R.A., Straat Marleen, Witteveen Esther, Wieske Luuk, Hoogendijk Arie J., Huson Mischa A., Scicluna Brendon P., van der Poll Tom, van Vught Lonneke A., Wiewel Maryse A., Bonten Marc J.M., Frencken Jos F., Klein Klouwenberg Peter M.C., Koster-Brouwer Maria E., Ong David S.Y., Verboom Diana M., 1 Dec 2018 In: Annals of Intensive Care. 8 8 p.

© 2019  

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