dr. S.G. (Sjoerd) Elias

dr. S.G. (Sjoerd) Elias

Associate Professor
dr. S.G. (Sjoerd) Elias
  • Epi Kanker Team C
  • Julius Center Research Program Cancer
  • Julius Center Research Program Cancer

Research Programs

Strategic Program Cancer



I obtained my MSc in Clinical Epidemiology at the Netherlands Institute for Health Sciences (2002), and my PhD at Utrecht University (2003). Following graduation from Medical School in 2005 I worked as a resident in radiology (Gelre Ziekenhuizen Apeldoorn, the Netherlands, 2006-2007). A personal Dutch Cancer Society Research Fellowship (2009-2013) enabled me to work as a visiting scientist at the Molecular Imaging Program at Stanford (professor SS Gambhir), the Department of Radiology and Biomedical Imaging at the University of California San Francisco (professor NM Hylton), and the Department of Molecular Pathology at the Netherlands Cancer Institute (professor LJ van't Veer). Since 2008, I work as a Clinical Epidemiologist in the research programs Cancer and Methodology at the Julius Center for Health Sciences and Primary Care, since 2018 as Associate Professor. Furthermore, I have more than ten years of experience in teaching and coordinating courses in clinical epidemiology, both nationally as well as internationally. Since 2020 I am coordinator of the PhD program Clinical and Translational Oncology, and since 2021 I am coordinator of the Research Program Cancer and management team member of the Epidemiology department of the Julius Center, as well as board member of the UMC Utrecht Strategic Program Cancer.

Interests and Focus

My main research focus is on the clinical evaluation and translation of biomarkers, particularly for cancer classification (i.e. diagnostic, prognostic, and predictive markers). These markers include emerging imaging technologies such as molecular imaging, omics-based tests, and organoids. I have both experience in preclinical research as well as applied clinical science, and have expertise and experience in the design and analysis of studies spanning all (translation) phases of biomarker development, as well as treatment studies (from phase I through phase III).

Side Activities

- Board member of the UMC Utrecht Strategic Program Cancer.

- Coordinator of the Research Program Cancer of the Julius Center.

- Coordinator of the PhD program Clinical and Translational Oncology.

- Coordinator of the SUMMA course "Wetenschappelijke Vorming - Onderzoeksmethodologie" ("applied clinical research").

- Coordinator of the MSc Epidemiology course "Advanced Topics in Causal Research: Confounding and Effect-Modification".

- Member of the Internal Review Committee Exploration of the Dutch Cancer Society.

- Member of the Dutch Association for Epidemiology (Vereniging voor Epidemiologie), Registration as Senior Epidemiologist (B) (SMBWO, 2006).

Fellowship and Awards

2016-2017: Jury member of the Talma Eykman award, UMC Utrecht.

2016-2017: Jury member of the Frits de Waard Penning, UMC Utrecht.

2014: Epidemiology teacher of the year, Epidemiology department, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht.

2014: Voted best lecturer of the year by the Selective Utrecht Medical Master program students, Utrecht University.

2013-2016: Methodologist of the Medical Ethical Review Board of the UMC Utrecht.

2013: UMC Utrecht Research Talent Program.

2012: Invitee, 2nd Inspire2Live annual conference at the Royal Netherlands Academy of Arts and Sciences (meeting of talented young international cancer scientists).

2011: René Vogels Foundation travel grant.

2009: Dutch Cancer Society Research Fellowship (four year personal grant).

Research Output (163)

Role of Up-Front Primary Tumor Resection and Tumor Sidedness in the Survival of Synchronous Metastatic Colon Cancer Patients

van der Kruijssen Dave E W, van Rooijen Karlijn L, Kurk Sophie A, de Wilt Johannes HW, Punt Cornelis J A, Vink Geraldine R, Elias Sjoerd G, Koopman Miriam 28 jul 2021, In: Digestive Surgery. p. 1-7 7 p.

Interaction Between Primary Tumor Resection, Primary Tumor Location, and Survival in Synchronous Metastatic Colorectal Cancer:A Population-Based Study

van der Kruijssen Dave E W, Brouwer Nelleke PM, van der Kuil Auke J S, Verhoeven Rob H A, Elias Sjoerd G, Vink Geraldine R, Punt Cornelis J A, de Wilt Johannes H W, Koopman Miriam 1 jul 2021, In: American Journal of Clinical Oncology. 44 , p. 315-324 10 p.

Prognostic value of breast MRI characteristics before and during neoadjuvant endocrine therapy in patients with ER+/HER2- breast cancer

Ragusi Max Aa, Winter-Warnars Gonneke Ao, Wesseling Jelle, Linn Sabine C., Beets-Tan Regina G., van der Velden Bas Hm, Elias Sjoerd G., Gilhuijs Kenneth Ga, Loo Claudette E. 1 jul 2021, In: The British journal of radiology. 94 , p. 1-10 1 p.

Patient-derived organoids as a predictive biomarker for treatment response in cancer patients

Wensink G Emerens, Elias Sjoerd G, Mullenders Jasper, Koopman Miriam, Boj Sylvia F, Kranenburg Onno W, Roodhart Jeanine M L 12 apr 2021, In: NPJ precision oncology. 5

Mode of progression after radioembolization in patients with colorectal cancer liver metastases

van Roekel Caren, Jongen Jennifer M J, Smits Maarten L J, Elias Sjoerd G, Koopman Miriam, Kranenburg Onno, Borel Rinkes Inne H M, Lam Marnix G E H 22 sep 2020, In: EJNMMI Research. 10

Quantifying the Mitigating Effects of Whole-Breast Radiotherapy and Systemic Treatments on Regional Recurrence Incidence Among Breast Cancer Patients

van Steenhoven Julia E C, Kuijer Anne, van Maaren Marissa C, Roos Marleen, Elias Sjoerd G, van Diest Paul J, Siesling Sabine, Smidt Marjolein L, Boersma Liesbeth J, van Dalen Thijs 1 sep 2020, In: Annals of Surgical Oncology. 27 , p. 3402-3411 10 p.

Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer according the trials within cohorts design: The MEDOCC-CrEATE trial

Schraa S., Van Rooijen K., Kruijssen D. V. D., Alarcon C. Rubio, Phallen J., Sausen M., Simmons J., Coupe V., Van Grevenstein H., Elias S., Verkooijen H., Bosch L., Van Den Broek D., Meijer G., Velculescu V., Fijneman R., Vink G., Koopman M. sep 2020, In: Annals of Oncology. 31 , p. S460-S460

Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE):study protocol for a trial within a cohort study

Schraa S J, van Rooijen K L, van der Kruijssen D E W, Rubio Alarcón C, Phallen J, Sausen M, Simmons J, Coupé V M H, van Grevenstein W M U, Elias S, Verkooijen H M, Laclé M M, Bosch L J W, van den Broek D, Meijer G A, Velculescu V E, Fijneman R J A, Vink G R, Koopman M, 20 aug 2020, In: BMC Cancer. 20 10 p.

Improving clinical management of colon cancer through CONNECTION, a nation-wide colon cancer registry and stratification effort (CONNECTION II trial):rationale and protocol of a single arm intervention study

van den Berg I, van de Weerd S, Roodhart J M L, Vink G R, van den Braak R R J Coebergh, Jimenez C R, Elias S G, van Vliet D, Koelink M, Hong E, van Grevenstein W M U, van Oijen M G H, Beets-Tan R G H, van Krieken J H J M, IJzermans J N M, Medema J P, Koopman M, 18 aug 2020, In: BMC Cancer. 20

Contralateral parenchymal enhancement on breast MRI before and during neoadjuvant endocrine therapy in relation to the preoperative endocrine prognostic index

Ragusi Max A A, Loo Claudette E, van der Velden Bas H M, Wesseling Jelle, Linn Sabine C, Beets-Tan Regina G, Elias Sjoerd G, Gilhuijs Kenneth G A 20 jul 2020, In: European Radiology. 30 , p. 6740-6748 9 p.

All research output

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