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dr. K. (Kathelijn) Fischer

dr. K. (Kathelijn) Fischer

Associate Professor - medical
dr. K. (Kathelijn) Fischer
  • Hematology/Van Creveldclinic

Research Programs

Biography

Biography

Kathelijn Fischer has been working at the University Medical Center Utrecht, both as a Paediatric Haematologist and a Clinical Epidemiologist.

Dr Fischer finished her medical training in 1988 is a registered paediatrician since 1994. Dr Fischer specialized in paediatric haematology and oncology in Utrecht, the Netherlands. Subsequently, she performed PhD research in haemophilia while training as a clinical epidemiologist. She published her thesis on ‘Treatment strategies in severe haemophilia: in search for the optimal treatment’ in 2001.

Dr Fischer supervises four PhD students and served as co-promotor for seven other PhD students in the field of haematology, neurology and gynaecology.

Dr Fischer is principal investigator in several international studies on long-term results of haemophilia treatment, and is the epidemiologist for the European Haemophilia Safety Surveillance Study (EUHASS-member of the steering committee) as well as for the European PedNet registry.

The specific areas of expertise and interest of dr Fischer include the epidemiology of haemophilia (including use of registries), prophylactic treatment, and outcome assessment in haemophilia care.

Side Activities

  • Membership of international working groups: International Prophylaxis Study Group (IPSG), European Association for Haemophilia and Allied Disorders (EAHAD; former EC member), she is a former co-chair of the FVIII/IX SSC subcommittee of the ISTH and participated in the group that drafted the Principles of Haemophilia Care.
  • Member of the National Haemophilia Registry Committee of the Dutch Haemophilia Treaters Board (NVHB)
  • Membership professional organisations: NVK (Dutch Paediatric Society,- section benign haematology), ISTH (International Society for Thrombosis and Haemostasis), WFH (World Federation for Haemophilia)
  • Section editor for Thrombosis and Haemostasis journal, member of the editorial board for Haemophilia journal

Fellowship and Awards

Bayer Haemophilia Special Project Award (2005)

Research Output (316)

Long-term joint outcomes in adolescents with moderate or severe haemophilia A

Schmidt David E, Michalopoulou Aikaterini, Fischer Kathelijn, Motwani Jayashree, Andersson Nadine G, Pergantou Helen, Ranta Susanna, 4 Aug 2022, In: Haemophilia. 28 , p. 1054-1061 8 p.

Desmopressin testing in von Willebrand disease:Lowering the burden

Heijdra Jessica M., Atiq Ferdows, Al Arashi Wala, Kieboom Quincy, Wuijster Esmee, Meijer Karina, Kruip Marieke J.H.A., Leebeek Frank W.G., Cnossen Marjon H., , Fijnvandraat K., Mathôt R. A.A., Polinder S., Coppens M., Tamminga R. Y.J., Meijer K., Laros-van Gorkom B. A.P., Brons P., Schols S. E.M., van der Meer F. J.M., Eikenboom H. C.J., Schutgens R. E.G., Fischer K., Heubel-Moenen F., Nieuwenhuizen L., Ypma P., Driessens M. H.E., Zwaan C. M., van Vliet I., Collins P. W., Liesner R., Chowdary P., Keeling D., Lock J., Hazendonk H. C.A.M., van Moort I., Preijers T., de Jager N. C.B., Goedhart M. C.H.J., Bukkems L. H., Cloesmeijer M. E., Janssen A. Aug 2022, In: Research and practice in thrombosis and haemostasis. 6

Validation of the pedHALshort and HALshort in Dutch children and adults with haemophilia

Kuijlaars Isolde A R, van der Net Janjaap, van Vulpen Lize F D, Driessens Mariette H E, Schols Saskia E M, Tan Melanie, Gouw Samantha C, Fischer Kathelijn 29 Jul 2022, In: Haemophilia. 28 , p. 1007-1015 9 p.

Predicting Individual Changes in Terminal Half-Life After Switching to Extended Half-Life Concentrates in Patients With Severe Hemophilia

Versloot Olav, Iserman Emma, Chelle Pierre, Germini Federico, Edginton Andrea N, Schutgens Roger E G, Iorio Alfonso, Fischer Kathelijn 21 Apr 2022, In: HemaSphere. 6 , p. 1-7

Modeling Benefits, Costs, and Affordability of a Novel Gene Therapy in Hemophilia A

Ten Ham Renske M T, Walker Sikon M, Soares Marta O, Frederix Geert W J, Leebeek Frank W G, Fischer Kathelijn, Coppens Michiel, Palmer Stephen J 28 Feb 2022, In: HemaSphere. 6 , p. 1-11

Is pharmacokinetic-guided dosing of desmopressin and von Willebrand factor-containing concentrates in individuals with von Willebrand disease or low von Willebrand factor reliable and feasible? A protocol for a multicentre, non-randomised, open label cohort trial, the OPTI-CLOT:To WiN study

Heijdra Jessica M., Al Arashi Wala, De Jager Nico C.B., Cloesmeijer Michael E., Bukkems Laura H., Zwaan Christian M., Leebeek Frank W.G., Mathôt Ron A.A., Cnossen Marjon H., Cnossen M. H., Leebeek F. W.G., Zwaan Christian M., Van Vliet I., Fijnvandraat K., Mathot R. A.A., Meijer K., Kruip M. J.H.A., S Polinder Polinder, Coppens M., Tamminga R. Y.J., Meijer K., Laros-Van B. A.P., Brons P., Schols S. E.M., Van Der Meer F. J.M., Eikenboom H. C.J., Schutgens R. E.G., Fischer K., Heubel-Moenen F., Nieuwenhuizen L., Ypma P., Driessens M. H.E., Pw Collins Collins, Liesner R., Chowdary P., Keeling D. 15 Feb 2022, In: BMJ Open. 12 , p. 1-6

LIVER-RELATED COMPLICATIONS DURING LONG-TERM HEPATITIS C VIRUS INFECTION AND AFTER SUCCESSFUL ANTIVIRAL TREATMENT IN PEOPLE WITH INHERITED BLEEDING DISORDERS

Isfordink C., van Erpecum K., Fischer K., van Vulpen L., Schutgens R., Arends J., Mauser-Bunschoten E. Feb 2022, In: Haemophilia. 28 , p. 18-18

Bone mineral density in haemophilia - a multicentre study evaluating the impact of different replacement regimens

Klintman Jenny, Akesson Kristina E, Holme Pål André, Fischer Kathelijn 7 Jan 2022, In: Haemophilia. 28 , p. 239-246 8 p.

Deep compartment models:A deep learning approach for the reliable prediction of time-series data in pharmacokinetic modeling

Janssen Alexander, Leebeek Frank W.G., Cnossen Marjon H., Mathôt Ron A.A., Fijnvandraat K., Coppens M., Meijer K., Schols S. E.M., Eikenboom H. C.J., Schutgens R. E.G., Beckers E. A.M., Ypma P., Kruip M. J.H.A., Polinder S., Tamminga R. Y.J., Brons P., Fischer K., van Galen K. P.M., Heubel-Moenen F. C.J.I., Nieuwenhuizen L., Driessens M. H.E., van Vliet I., Lock J., Hazendonk H. C.A.M., van Moort I., Heijdra J. M., Goedhart M. H.J., Al Arashi W., Preijers T., de Jager N. C.B., Bukkems L. H., Cloesmeijer M. E., Collins P. W., Liesner R., Chowdary P., Millar C. M., Hart D., Keeling D., 2022, In: CPT: Pharmacometrics and Systems Pharmacology. 11 , p. 934-945 12 p.

Reduced cardiovascular morbidity in patients with hemophilia:results of a 5-year multinational prospective study

Van Der Valk Paul, Makris Michael, Fischer Kathelijn, Tait Robert C, Chowdary Pratima, Collins Peter W, Meijer Karina, van Vulpen Lize F D, Mauser-Bunschoten Eveline, Schutgens Roger E G 8 Dec 2021, In: Blood Advances. 6 , p. 902-908 7 p.

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