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M.I. (Mirjam) Geerlings

M.I. (Mirjam) Geerlings

Associate Professor
M.I. (Mirjam) Geerlings
  • Julius Center, dept. Epidemiology & Health Economics

Research Programs

Biography

Biography

I received my MSc degree in Neuropsychology and PhD degree in Epidemiology from the VU medical center Amsterdam, the Netherlands. From 2000 until 2002, I worked as a post-doc at the Department of Epidemiology & Biostatistics of the Erasmus Medical Center, Rotterdam where I studied steroid hormones as risk factors for dementia using data from the Rotterdam Study. From 2002 until 2022, I worked at the Julius Center for Health Sciences and Primary Care (University Medical Center Utrecht), first as Assistant Professor, and since 2006 as Associate Professor where I initiated, conducted, and supervised research within the department of Epidemiology. I also developed, coordinated and taught epidemiology courses within the Biomedical Sciences (BSc), Medicine (BSc and MSc), and MSc Epidemiology curriculum. I supervised around 40 MSc and BSc students during their research and completing their MSc or BSc thesis. Additionally, I mentored a substantial number of research assistants, PhD candidates, and postdoctoral fellows. I am a PI of the research programs Circulatory Health (research theme Cerebrovascular disease) and Brain within the UMC Utrecht. 

Since May 2022, I am head of the section Research and member of the management team of the department of General Practice at Amsterdam UMC. Since January 2023, I am affiliated with the Julius Center (UMC Utrecht) as a guest researcher.

Within the UMC Utrecht, I lead the SMART-MR study, a sub-study of the UCC-SMART study. The SMART-MR study (SMART-MR study) is an ongoing prospective cohort study among 1309 non-demented, independently living middle-aged to older adults with manifest arterial disease, aimed to investigate determinants and consequences of brain changes on MRI, including depression and cognitive decline. Individuals were assessed at up to three visits: at baseline, 4 years, and 12 years follow-up. I am also PI of the Medea 7T study, a cohort study in the UMC Utrecht, aimed to investigate determinants and consequences of microstructural brain abnormalities on 7 tesla brain MRI. With the UCC-SMART study and SMART-MR study I participate in national and international consortia, including the Netherlands Consortium for Dementia Cohorts (NCDC), the Psychosocial factors and cancer incidence (PSY-CA) consortium, and the CHARGE consortium. Starting in 2023, I also participate in the BIRD-NL consortium.

Internationally, I have longstanding collaborations with the Laboratory of Epidemiology and Population Sciences, National Institute on Aging, USA (dr. Lenore Launer) where I published using data from the Honolulu Asia Aging Study and the AGES-Reykjavik Study.

 

Research line

Epidemiology of cerebrovascular disease and brain health.

 

Publications

in PubMed:

geerlings mi OR (geerlings m AND (gerritsen OR nazareth)) OR (ggeerlings mi AND Scarth M AND Vonk JM AND Gerritsen L) - Search Results - PubMed (nih.gov)

 

Side Activities

Committees

Chair or vice-chair

2019                 Chair of the Talma Eykman Master’s Thesis Awards committee (University Medical Center Utrecht).

2014–2017        Chair of the Veni ZonMw programme committee (Innovational Research Incentives Scheme) of The Netherlands Organisation for Scientific Research (NWO).

2013                 Vice-chair of the Veni ZonMw programme committee (Innovational Research Incentives Scheme) of The Netherlands Organisation for Scientific Research (NWO).

 

Member

2023             Member of the Vidi ZonMw programme committee (Innovational Research Incentives Scheme) of The Netherlands Organisation for Scientific Research (NWO).

2021-2022    Member of the ZonMw Off Road committee.

2021-2022    Substitute methodological member of the Institutional Review Board (Independent Ethics Committee) of the University Medical Center Utrecht.

2018             Member of the Talma Eykman Master’s Thesis Awards committee (University Medical Center Utrecht).

2017-2021    Member of the Alzheimer Nederland fellowship grant programme committee.

2016-2022    Member of the examiner board of the curriculum Medicine (Examencommissie Geneeskunde) (University Medical Center Utrecht).

2014             Member of the Earth and Life Sciences Open Programme committee (ALW-Open programma) of The Netherlands Organisation for Scientific Research (NWO).

2011             Member of the Veni ZonMw programme committee (Innovational Research Incentives Scheme) of The Netherlands Organisation for Scientific Research (NWO).

2011-2017    Substitute methodological member of the Institutional Review Board (Independent Ethics Committee) of the University Medical Center Utrecht.

2007-2011    Methodological member of the Institutional Review Board (Independent Ethics Committee) of the University Medical Center Utrecht.

 

Society memberships

2016-present                 Member of the sounding board of the Dutch Network of Women Professors (klankbordgroep UHD Landelijk Netwerk Vrouwelijke Hoogleraren)

2012-present                 Dutch Network of Women Professors (Landelijk Netwerk Vrouwelijke Hoogleraren)

2009-present                International Society to Advance Alzheimer Research and Treatment (ISTAART)

2007-present                International Society for Vascular, Cognitive and Behavioural Disorders (VasCog)

Research Output (247)

Carotid Artery Stenosis and Progression of Hemispheric Brain Atrophy:The SMART-MR Study

Ghaznawi Rashid, Rissanen Ina, de Bresser Jeroen, Kuijf Hugo J, Zuithoff Nicolaas P A, Hendrikse Jeroen, Geerlings Mirjam I, 12 Sep 2022, In: Cerebrovascular diseases (Basel, Switzerland). 52 , p. 226-233 8 p.

White matter hyperintensity shape is associated with cognitive functioning - the SMART-MR study

Zwartbol Maarten H T, Ghaznawi Rashid, Jaarsma-Coes Myriam, Kuijf Hugo, Hendrikse Jeroen, de Bresser Jeroen, Geerlings Mirjam I, 23 Aug 2022, In: Neurobiology of Aging. 120 , p. 81-87 7 p.

Effect of physical exercise on cognitive function after chemotherapy in patients with breast cancer:a randomized controlled trial (PAM study)

Koevoets E W, Schagen S B, de Ruiter M B, Geerlings M I, Witlox L, van der Wall E, Stuiver M M, Sonke G S, Velthuis M J, Jobsen J J, Menke-Pluijmers M B E, Göker E, van der Pol C C, Bos M E M M, Tick L W, van Holsteijn N A, van der Palen J, May A M, Monninkhof E M, 26 May 2022, In: Breast Cancer Research. 24

Microinfarcts in the Deep Gray Matter on 7T MRI:Risk Factors, MRI Correlates, and Relation to Cognitive Functioning-The SMART-MR Study

Ghaznawi R, Zwartbol M H T, de Bresser J, Kuijf H J, Vincken K L, Rissanen I, Geerlings M I, Hendrikse J, 26 May 2022, In: AJNR. American journal of neuroradiology. 43 , p. 829-836 8 p.

Intracranial atherosclerosis in pseudoxanthoma elasticum:A case-control study

Lucci Carlo, van den Beukel Tim C, Bartstra Jonas W, Zwanenburg Jaco, van der Kolk Anja, Takx Richard, Hendrikse Jeroen, Geerlings Mirjam I, Bos Daniel, Spiering Wilko, de Jong Pim A 15 Apr 2022, In: Atherosclerosis. 350 , p. 19-24 6 p.

Automatic quantification of perivascular spaces in T2-weighted images at 7 T MRI

Verbeek-Spijkerman Jolanda, Zwanenburg J. J.M., Bouvy W. H., Geerlings M. I., Biessels G. J., Hendrikse J., Luijten P. R., Kuijf H. J. 13 Apr 2022, In: Cerebral Circulation - Cognition and Behavior. 3 , p. 1-9

Depressive symptom profiles predict dementia onset and brain pathology in older persons. The AGES-Reykjavik study

Gerritsen Lotte, Sigurdsson Sigurdur, Jonsson Palmi V, Gudnason Vilmundur, Launer Lenore J, Geerlings Mirjam I Mar 2022, In: Neurobiology of Aging. 111 , p. 14-23 10 p.

Depression in Stroke Survivors:Ten-Year Follow-Up. Determinants of the Natural Course of Depressive Symptoms in Stroke Survivors in the Netherlands: The SMART-Medea Study

de Bekker A., Geerlings M. I., Uitewaal-Poslawsky I. E., de Man-van Ginkel J. M. Mar 2022, In: Journal of Stroke and Cerebrovascular Diseases. 31

The role of cognitive and brain reserve in memory decline and atrophy rate in mid and late-life:The SMART-MR study

Vonk Jet M J, Ghaznawi Rashid, Zwartbol Maarten H T, Stern Yaakov, Geerlings Mirjam I, 31 Jan 2022, In: Cortex. 148 , p. 204-214 11 p.

Patients with diffuse idiopathic skeletal hyperostosis have an increased burden of thoracic aortic calcifications

Harlianto Netanja I., Westerink Jan, Hol Marjolein E., Wittenberg Rianne, Foppen Wouter, Van Der Veen Pieternella H., Van Ginneken Bram, Verlaan Jorrit Jan, De Jong P. A., Mohamed Hoesein Firdaus A.A., Asselbergs F. W., Nathoe H. M., De Borst G. J., Bots M. L., Geerlings M. I., Emmelot M. H., De Jong P. A., Leiner T., Lely A. T., Van Der Kaaij N. P., Kappelle L. J., Ruigrok Y. M., Verhaar M. C., Visseren F. L.J. 2022, In: Rheumatology advances in practice. 6 , p. rkac060

All research output

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