dr. M.L. Houben

Assistant Professor - medical

  • Cluster D
  • Integral pediatrics patient care

dr. M.L. Houben

Research Programs


Michiel was trained as a medical doctor (2002) and pediatrician (2010) and as a clinical epidemiologist (2009) at the UMC Utrecht. In 2011 he obtained his PhD on his thesis entitled: RSV Bronchiolitis in Healthy Term Infants, Pathogenesis and Prediction. Since 2010 he works as a general pediatrician in the Wilhelmina Children’s Hospital (UMC Utrecht) and since 2014 he is head of the section of general en social pediatrics. He is the pediatrician and coordinator of the 22q11.2 deletion syndrome childhood outward patient clinic and studies the heterogeneity and prognostic factors of this syndrome, in close collaboration with colleagues of other pediatric, surgery, psychiatric, psychology and genetics specialties. He is also involved in several further studies on the healthy term birth (amniotic fluid) cohort from his PhD trajectory.

Side Activities

    • member of Infectious Diseases section and Geneticis and Congenital Anomalies section of Dutch Pediatric Association (NVK secties I&I en Erfelijke en Aangeboren Afwijkingen)

    • 2014-present Chair of Working Group on Development of Guideline for central venous catheter use, WKZ

    • 2013-present Chair of Working Group on Pediatric orthopedic care; quality and routing, WKZ

    • 2013-present Pediatrician member of Working Group on Medication, WKZ

Fellowship and Awards

    • 2011-12 PhD Curriculum of Training Upcoming Leaders in Pediatric Science (TULIPS), competitive selection
    • 2011 NVK Masterclass, Prof Dr B Prakken, Prof Dr HJ Verkade, competitive selection

    • 2007 NVK Young Investigators, award best poster presentation

    • 2005 ESPID Fellowship Award

    • 2000 UMC Utrecht Students’ Scientific meeting, 2nd price for oral presentation

    • 1992 Theoretical Mathematics Olympiads, team competition, national winner

    • 1992 Applied Mathematics Olympiads, team competition, national winner

Research Output (28)

Scoliosis in association with the 22q11.2 deletion syndrome:an observational study

Homans Jelle F, Baldew Vyaas G M, Brink Rob C, Kruyt Moyo C, Schlösser Tom P C, Houben Michiel L, Deeney Vincent F X, Crowley Terrence B, Castelein René M, McDonald-McGinn Donna M jan 2019, In: Archives of Disease in Childhood. 104 , p. 19-24 6 p.

Growth impairment in Dutch children with 22q11.2 Deletion syndrome

Knobel C., Klomberg Renz, Houben ML, van Santen HM, Bok G. 6 nov 2018,

Metabolomic Profile of Amniotic Fluid and Wheezing in the First Year of Life—A Healthy Birth Cohort Study

Carraro Silvia, Baraldi Eugenio, Giordano Giuseppe, Pirillo Paola, Stocchero Matteo, Houben Michiel, Bont Louis 1 mei 2018, In: Journal of Pediatrics. 196 , p. 264-269.e4

Association of Maternal Prepregnancy Body Mass Index With Placental Histopathological Characteristics in Uncomplicated Term Pregnancies

Brouwers Laura, Franx Arie, Vogelvang Tatjana E, Houben Michiel L, van Rijn Bas B, Nikkels Peter Gj 1 jan 2018, In: Pediatric and Developmental Pathology. 22 , p. 45-52 8 p.

The Value of a Checklist for Child Abuse in Out-of-Hours Primary Care:To Screen or Not to Screen

Schouten Maartje Cm, van Stel Henk F, Verheij Theo Jm, Houben Michiel L, Russel-Kampschoer IMB, Nieuwenhuis Edward Es, van de Putte Elise M 2017, In: PLoS ONE [E]. 12

Human amniotic fluid antibodies protect the neonate against respiratory syncytial virus infection

Jacobino Shamir R., Nederend Maaike, Hennus Marije, Houben Michiel L. , Ngwuta Joan O., Viveen Marco, Coenjaerts Frank E.J., Hack C. Erik, van Neerven R. J Joost, Graham Barney S., Bont Louis, Leusen Jeanette H W nov 2016, In: Journal of Allergy and Clinical Immunology. 138 , p. 1477–1480.e5

Porphyromonas gingivalis within placental villous mesenchyme and umbilical cord stroma is associated with adverse pregnancy outcome

Vanterpool Sizzle F., Been Jasper V., Houben Michiel L. , Nikkels Peter G J, De Krijger Ronald R., Zimmermann Luc J I, Kramer Boris W., Progulske-Fox Ann, Reyes Leticia 5 jan 2016, In: PLoS ONE [E]. 11

Placental characteristics in women with polycystic ovary syndrome

Koster Maria P H, de Wilde Marlieke A, Veltman-Verhulst Susanne M, Houben ML, Nikkels Peter G J, van Rijn Bas B, Fauser Bart C J M dec 2015, In: Human Reproduction. 30 , p. 2829-2837 9 p.

Rhinovirus wheezing illness in infancy is associated with medically attended third year wheezing in low risk infants:results of a healthy birth cohort study

de Winter Janneke J H, Bont Louis J , Wilbrink Berry, van der Ent Cornelis K, Smit Henriette A, Houben Michiel L. dec 2015, In: Immunity, inflammation and disease. 3 , p. 398-405 8 p.

All Research Output (28)