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prof. dr. R.H.J. Houwen

Full Professor

  • Gastroenterology & Hepatology research 3

prof. dr. R.H.J. Houwen

Research Programs

Biography

Professor Houwen is kinderarts-MDL sinds 1988 en beoefent het vak in de volle breedte, waarbij er met name interesse is voor leverziekten en genetisch bepaalde aandoeningen van de tractus digestivus.

Wetenschappelijk onderzoek: Ophelderen pathofysiologie van genetisch bepaalde ziekten lever en tractus digestivus en het ontwikkelen van behandelmethoden hiervoor.

  • Studie geneeskunde, Erasmus Universiteit Rotterdam
  • Opleiding tot kinderarts,  Sophia Kinderziekenhuis Rotterdam
  • Opleiding tot  kinderarts-MDL, afdeling kindergeneeskunde en kinder-MDL, UMCG
  • Research and clinical fellow, Hospital for Sick Children Toronto
  • Staflid afdeling kinder-MDL, UMCU/WKZ
  • Hoogleraar Pediatric Gastroenterology

 

Side Activities

  • Lid van de Medische Adviesraad van:

    • Nederlandse Coeliakie Vereniging

     Wetenschappelijke verenigingen:

    • Sectie Kinder-MDL van de Nederlandse Vereniging voor Kindergeneeskunde (S-MDL)
    • Nederlandse Vereniging voor Hepatologie (NVH)
    • Nederlandse Vereniging voor Gastro-enterologie (NVGE)
    • European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN)
    • European Association for the Study of Liver Diseases (EASL)
    • American Association for the Study of Liver Diseases (AASLD)
    • American Gastroenterological Association (AGA)

Research Output (277)

Proteolytic Immuno-SRM Analysis of ATP7B in dried blood spots (DBS) for screening and diagnosis of Wilson Disease (WD)

Collins Christopher, Dayuha Remwilyn, Duong Phi, Horslen Simon P., Camarata Michelle, Coskun Ayse K., Houwen Roderick, Pop Tudor, Zoller Heinz, Weiss Karl Heinz, Schilsky Michael L., Ferenci Peter, Hahn Sihoun nov 2020, In: Hepatology. 72 , p. 869A-870A

p.P1379S, a benign variant with reduced ATP7B protein level in Wilson Disease

Yi Fan, Poskanzer Sheri A, Myers Candace T, Thies Jenny, Collins Christopher J, Dayuha Remwilyn, Duong Phi, Houwen Roderick, Hahn Si Houn jul 2020, In: JIMD Reports. 54 , p. 32-36 5 p.

Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids

Vonk Annelotte M, van Mourik Peter, Ramalho Anabela S, Silva Iris A L, Statia Marvin, Kruisselbrink Evelien, Suen Sylvia W F, Dekkers Johanna F, Vleggaar Frank P, Houwen Roderick H J, Mullenders Jasper, Boj Sylvia F, Vries Robert, Amaral Margarida D, de Boeck Kris, van der Ent Cornelis K, Beekman Jeffrey M 19 jun 2020, In: STAR protocols. 1 31 p.

Potential of ileal bile acid transporter inhibition as a therapeutic target in Alagille syndrome and progressive familial intrahepatic cholestasis

Kamath Binita M, Stein Philip, Houwen Roderick H J, Verkade Henkjan J 3 jun 2020, In: Liver International. 40 , p. 1812-1822 11 p.

Metabolic fingerprinting reveals extensive consequences of GLS hyperactivity

Rumping Lynne, Pras-Raves Mia L, Gerrits Johan, Tang Yuen Fung, Willemsen Marcel A, Houwen Roderick H J, van Haaften Gijs, van Hasselt Peter M, Verhoeven-Duif Nanda M, Jans Judith J M 1 mrt 2020, In: Biochimica et biophysica acta-General subjects. 1864

Erratum to “Systematic review of progressive familial intrahepatic cholestasis” (Clinics and Research in Hepatology and Gastroenterology (2019) 43(1) (20–36), (S2210740118301499), (10.1016/j.clinre.2018.07.010))

Baker Alastair, Kerkar Nanda, Todorova Lora, Kamath Binita M, Houwen Roderick H J 8 jan 2020, In: Clinics and Research in Hepatology and Gastroenterology. 44 , p. 115 1 p.

Correction:Aminoacyl-tRNA synthetase deficiencies in search of common themes

Fuchs Sabine A, Schene Imre F, Kok Gautam, Jansen Jurriaan M, Nikkels Peter G J, van Gassen Koen L I, Terheggen-Lagro Suzanne W J, van der Crabben Saskia N, Hoeks Sanne E, Niers Laetitia E M, Wolf Nicole I, de Vries Maaike C, Koolen David A, Houwen Roderick H J, Mulder Margot F, van Hasselt Peter M 2020, In: Genetics in Medicine.

Comparative effectiveness of common therapies for Wilson disease:A systematic review and meta-analysis of controlled studies

Appenzeller-Herzog Christian, Mathes Tim, Heeres Marlies L.S., Weiss Karl Heinz, Houwen Roderick H.J., Ewald Hannah 1 nov 2019, In: Liver International. 39 , p. 2136-2152 17 p.

Is meconium ileus associated with worse outcomes in cystic fibrosis?

Sathe Meghana, Houwen Roderick 25 okt 2019, In: Journal of Cystic Fibrosis. 18 , p. 746 1 p.

Disease progression in paediatric- and adult-onset sclerosing cholangitis:Results from two independent Dutch registries

Joosse Maria E., Haisma Sjoukje M., Sterk Marlou F.M., van Munster Kim N., Ponsioen Cyriel I.J., Houwen Roderick H.J., Koot Bart G.P., de Meij Tim, van Rheenen Patrick F., de Koning Barbara A.E. 1 sep 2019, In: Liver International. 39 , p. 1768-1775 8 p.

All Research Output (277)