dr. A.T. (Titia) Lely

Associate Professor - medical

  • Birth Center Obstetrics - Medical

Research Programs


With the combination of a PhD in Nephrology (UMCG) and Post-doctoral training in preeclampsia field (Harvard), Titia Levy developed a unique translational research line with focus on the kidney during and after hypertensive-complicated pregnancies within Cardiovascular research line of the UMC Utrecht.

Her clinical work as gynaecologist in the Obstetrical department has its focus on Maternal Medicine and especially care for pregnancy in women with kidney disease. As young-PI, she works in close collaboration with the department of Nephrology, Vascular Medicine and Epidemiology (Julius Center). Furthermore, as a result of her post-doctoral period in Groningen several projects are in close collaboration with the UMCG.

It is her aim to improve patient care during and after pregnancy for cardiovascular and renal patients. With her translational research line mainly focussing on the kidney and vascular bed, she hopes to improve with research from bench to bedside and vice-versa renal and pregnancy outcomes in the long run.

Side Activities

  • Elective fellowship Maternal and Fetal Medicine at Mount Sinai Hospital

Fellowship and Awards

  • Dutch Kidney Foundation, Innovation grant, € 100.000 (2017)

    ZonMW, Clinical fellowship, personal carrier grant € 160.000 (2013) 
    Dutch Kidney Foundation, Kolff, personal junior post-doc grant € 170.000 (2011)
    Personal MD/PhD Grant - UMCG - K. Holwerda - Hydrogen sulphide: a gas as therapy for PE?
    (Lely: supervisor), 170.000 euro, co-PI (2011) 
    Mandem Stipendium, personal post-doc grant UMCG € 100.000 (2010)
    Personal MD/PhD Grant - UMCG - A.M. van der Graaf - Vascular and renal alterations in relation
    to PE: from prediction to renal disease with focus on the AT-1 receptor (Lely: supervisor), 170.000 euro, co-PI (2010)

Research Output (38)

Sodium Thiosulfate in the Pregnant Dahl Salt-Sensitive Rat, a Model of Preeclampsia

Terstappen Fieke, Clarke Sinéad M, Joles Jaap A, Ross Courtney A, Garrett Michael R, Minnion Magdalena, Feelisch Martin, Goor Harry van, Sasser Jennifer M, Lely A Titia 1 feb 2020, In: Biomolecules. 10 14 p.

Conflicting Effects of Fetal Growth Restriction on Blood Pressure Between Human and Rat Offspring:A Meta-Analysis

Kooiman Judith, Terstappen Fieke, van Wagensveld Lilian, Franx Arie, Wever Kimberley E, Roseboom Tessa J, Joles Jaap A, Gremmels Hendrik, Lely A Titia 1 jan 2020, In: Hypertension (Dallas, Tex. : 1979). 75 , p. 806-818 13 p.

Pregnancy in Advanced Kidney Disease:Clinical Practice Considerations on a Challenging Combination

Snoek Rozemarijn, van der Graaf Rieke, Meinderts Jildau R, van Reekum Franka, Bloemenkamp Kitty W M, Knoers Nine V A M, van Eerde Albertien M, Lely A Titia 2020, In: Nephron. 144 , p. 185-189 5 p.

Intracranial Atherosclerotic Burden on 7T MRI Is Associated with Markers of Extracranial Atherosclerosis:The SMART-MR Study

Zwartbol M. H. T., Geerlings M. I., Ghaznawi R., Hendrikse J., van der Kolk A. G., Asselbergs F. W., Nathoe H. M., de Borst G. J., Bots M. L., Emmelot M. H., de Jong P. A., Leiner T., Lely A. T., van der Kaaij N. P., Kappelle L. J., Ruigrok Y. M., Verhaar M. C., Visseren F. L. J., Westerink J., 5 dec 2019, In: American Journal of Neuroradiology. 40 , p. 2016-2022 7 p.

Maternal and neonatal bleeding complications in relation to peripartum management in women with Von Willebrand disease:A systematic review

Punt M. C., Waning M. L., Mauser-Bunschoten E. P., Kruip M. J.H.A., Eikenboom J., Nieuwenhuizen L., Makelburg A. B.U., Driessens M. H.E., Duvekot J. J., Peters M., Middeldorp J. M., Bloemenkamp K. W.M., Schutgens R. E.G., Lely A. T., Van Galen K. P.M. 24 okt 2019, In: Blood Reviews. 39 9 p.

SAFE@HOME – Feasibility study of a telemonitoring platform combining blood pressure and preeclampsia symptoms in pregnancy care

van den Heuvel Josephus F.M., Kariman Shariva S., van Solinge Wouter W., Franx Arie, Lely A. Titia, Bekker Mireille N. 15 jul 2019, In: European Journal of Obstetrics, Gynecology and Reproductive Biology. 240 , p. 226-231 6 p.

The effect of computerized decision support systems on cardiovascular risk factors:A systematic review and meta-analysis

Groenhof T. Katrien J., Asselbergs Folkert W., Groenwold Rolf H. H., Grobbee Diederick E., Visseren Frank L. J., Bots Michiel L., Asselbergs Folkert W., Nathoe H. M., de Borst G. J., Bots Michiel L., Geerlings M. I., Emmelot M. H., de Jong P. A., Leiner T., Lely A. T., van der Kaaij N. P., Kappelle L. J., Ruigrok Y. M., Verhaar M. C., Visseren Frank L. J., Westerink J. 10 jun 2019, In: BMC Medical Informatics and Decision Making. 19 , p. 108

Diagnosing and treating antiphospholipid syndrome:a consensus paper

Limper M, de Leeuw K, Lely A T, Westerink J, Teng Y K O, Eikenboom J, Otter S, Jansen A J G, V D Ree M, Spierings J, Kruyt N D, van der Molen R, Middeldorp S, Leebeek F W G, Bijl M, Urbanus R T apr 2019, In: The Netherlands journal of medicine. 77 , p. 98-108 11 p.

Prenatal Sildenafil Therapy Improves Cardiovascular Function in Fetal Growth Restricted Offspring of Dahl Salt-Sensitive Rats

Terstappen Fieke, Spradley Frank T, Bakrania Bhavisha A, Clarke Sinéad M, Joles Jaap A, Paauw Nina D, Garrett Michael R, Lely A Titia, Sasser Jennifer M 4 mrt 2019, In: Hypertension (Dallas, Tex. : 1979). 73 , p. 1120-1127 8 p.

Validation of the iHealth Track and Omron HEM-9210T automated blood pressure devices for use in pregnancy

van den Heuvel JFM, Lely A. Titia, Franx Arie, Bekker Mireille N. 1 jan 2019, In: Pregnancy Hypertension. 15 , p. 37-41 5 p.

All Research Output (38)