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prof. dr. S.M.A. Lens

Full Professor

  • Group Lens, section Molecular Cancer Research

Research Programs

Side Activities

  • Organizer of the EMBO Workshop on Chromosome Segregation and Aneuploidy (2013)

    Member of the NWO Rubicon evaluation committee (2015)

    Member of the NWO-ALW Open Program evaluation committee (2016)

    ERC Advanced Grant Evaluation panel member (2017/2018)

    Member evaluation committee of the Max Puritz Labs, Univ. of Vienna, Austria (2019)

    Member of organizing committee of Life2020 (NWO)

    PI of Oncode Institute

Research Output (73)

Human chromosome-specific aneuploidy is influenced by DNA-dependent centromeric features

Dumont Marie, Gamba Riccardo, Gestraud Pierre, Klaasen Sjoerd, Worrall Joseph T., De Vries Sippe G., Boudreau Vincent, Salinas-Luypaert Catalina, Maddox Paul S., Lens Susanne M.A., Kops Geert J.P.L., McClelland Sarah E., Miga Karen H., Fachinetti Daniele 15 jan 2020, In: EMBO Journal. 39 21 p.

PLK1 plays dual roles in centralspindlin regulation during cytokinesis

Adriaans Ingrid E, Basant Angika, Ponsioen Bas, Glotzer Michael, Lens Susanne M A 1 apr 2019, In: Journal of Cell Biology. 218 , p. 1250-1264 15 p.

Cytokinesis defects and cancer

Lens Susanne M.A., Medema René H. 1 jan 2018, In: Nature Reviews Cancer. 19 , p. 32-45 14 p.

Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore-microtubule dynamics

DeLuca Keith F., Meppelink Amanda, Broad Amanda J., Mick Jeanne E., Peersen Olve B., Pektas Sibel, Lens Susanne M.A., DeLuca Jennifer G. 1 jan 2018, In: Journal of Cell Biology. 217 , p. 163-177 15 p.

The ins and outs of Aurora B inner centromere localization

Hindriksen Sanne, Lens Susanne M.A., Hadders Michael A. 22 dec 2017, In: Frontiers in Cell and Developmental Biology. 5

Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells

Hindriksen Sanne, Bramer Arne J, Truong My Anh, Vromans Martijn J M, Post Jasmin B, Verlaan-Klink Ingrid, Snippert Hugo J , Lens Susanne M A, Hadders Michael A 2017, In: PLoS ONE [E]. 12

Inner centromere localization of the CPC maintains centromere cohesion and allows mitotic checkpoint silencing

Hengeveld Rutger C C, Vromans Martijn J M, Vleugel Mathijs, Hadders Michael A, Lens Susanne M A 2017, In: Nature Communications [E]. 8

Compound heterozygous NEK1 variants in two siblings with oral-facial-digital syndrome type II (Mohr syndrome)

Monroe Glen R, Kappen Isabelle Fpm, Stokman Marijn F, Terhal Paulien A, van den Boogaard Marie-José H, Savelberg Sanne Mc, van der Veken Lars T, van Es Robert J J, Lens Susanne M, Hengeveld Rutger C, Creton Marijn A, Janssen Nard G, Mink van der Molen Aebele B, Ebbeling Michelle B, Giles Rachel H, Knoers Nine V, van Haaften Gijs 17 aug 2016, In: European Journal of Human Genetics. 24 , p. 1752–1760

Tetraploid/Diploid Mosaicism in Cultured Genital Skin Fibroblasts:Is It Causally Related to Penoscrotal Hypospadias

Giltay Jacques C., Klijn Aart J., de Jong Tom P V M, Kats Peter, van Breugel Marjolein, Lens Susan, Vromans Martijn, Van Der Veken Lars T., Hochstenbach Ron 1 jul 2016, In: Molecular Syndromology. 7 , p. 153-159 7 p.

Chromosome segregation regulation in human zygotes:Altered mitotic histone phosphorylation dynamics underlying centromeric targeting of the chromosomal passenger complex

Van De Werken C., Avo Santos M., Laven J. S E, Eleveld C., Fauser B. C J M, Lens S. M A, Baart E. B. 1 okt 2015, In: Human Reproduction. 30 , p. 2275-2291 17 p.

All Research Output (73)