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dr. C.A. (Caroline) Lindemans

dr. C.A. (Caroline) Lindemans

Assistant Professor - medical
dr. C.A. (Caroline) Lindemans
  • SCT patient care

Biography

Biography

Caroline Lindemans, MD, PhD is a pediatrician, BMT specialist  and pediatric immunologist in the UMC Utrecht. Appointed as a consultant in HCT she has a special  research interest in graft versus host disease, intestinal toxicity, it’s prevention and therapy.  After receiving a KWF fellowship grant she recently worked at Memorial Sloan Kettering Cancer Center in the Research groups of Marcel van den Brink  and Alan Hanash resulting in a first author Nature paper, published December 2015. She has ongoing collaborations with these groups and is currently expanding this line of research in the UMC Utrecht.  Caroline is an active member of various international working committees (e.g. EBMT, CIBMTR: chair of one of the CIBMTR working committees).

Side Activities

  • Co-chair CIBMTR working committee Infection and Immunity February 2014—Feb 2017
  • Medical Consultant Chimerix europe (Brincidofovir studies): 2015-heden

Fellowship and Awards

  • 2000 Wilhelmina Children's Hospital Student Research Prize
  • 2010 ASBMT Travel grant for young investigators $500
  • 2012 Abstract award winner international cord blood symposium
  • 2012 UMC Utrecht mobilization grant  €20.000 euro
  • 2013 Wilhelmina Children’s hospital Fund: Leading ladies  research stimulation grant €125.000 euro
  • 2013 Travel Stipendium Nijbakker Morra Foundation €9.600 euro
  • 2013 KWF (Dutch Cancer Society) Clinical fellowship Grant €250.000 euro. To study tissue regeneratation in GVHD.
  • 2014 ASH Abstract Achievement Award

Research Output (109)

The Effect of Genetic HLA Matching on Liver Transplantation Outcome:A Systematic Review and Meta-Analysis

Kok Gautam, Ilcken Eveline F, Houwen Roderick H J, Lindemans Caroline A, Nieuwenhuis Edward E S, Spierings Eric, Fuchs Sabine A Sep 2023, In: Annals of surgery open : perspectives of surgical history, education, and clinical approaches. 4 , p. 1-7

Meningococcal ACWY conjugate vaccine immunogenicity in adolescents with primary or secondary immune deficiencies, a prospective observational cohort study

Ohm Milou, van Straalen Joeri W, de Joode-Smink Gerrie, van Montfrans Joris, Bartels Marije, van Wildenbeest Joanne G, Lindemans Caroline A, Wennink Roos Aw, de Boer Joke H, Sanders Elisabeth Am, Verduyn-Lunel Frans M, Berbers Guy Am, Wulffraat Nico M, Jansen Marc H A 20 Jul 2023, In: Pediatric rheumatology online journal. 21 , p. 1-6

Busulfan target exposure attainment in children undergoing allogeneic hematopoietic cell transplantation:a single day versus a multiday therapeutic drug monitoring regimen

Bognàr T Tim, Kingma J S Jurjen, Smeijsters E H Erin, van der Elst K C M Kim, de Kanter C T M Klaartje, Lindemans C A Caroline, Egberts A C G Toine, Bartelink I H Imke, Lalmohamed A Arief Jul 2023, In: Bone Marrow Transplantation. 58 , p. 762-768 7 p.

Meningococcal ACWY conjugate vaccine immunogenicity and safety in adolescents with juvenile idiopathic arthritis and inflammatory bowel disease:A prospective observational cohort study

Ohm Milou, van Straalen Joeri W, Zijlstra Marieke, de Joode-Smink Gerrie, Jasmijn Sellies Anne, Swart Joost F, Vastert Sebastiaan J, van Montfrans Joris M, Bartels Marije, van Royen-Kerkhof Annet, Wildenbeest Joanne G, Lindemans Caroline A, Wolters Victorien, Wennink Roos A W, de Boer Joke H, Knol Mirjam J, Heijstek Marloes W, Sanders Elisabeth A M, Verduyn-Lunel Frans M, Berbers Guy A M, Wulffraat Nico M, Jansen Marc H A 15 May 2023, In: Vaccine. 41 , p. 3782-3789 8 p.

Chemotherapy-induced intestinal injury promotes Galectin-9-driven modulation of T cell function

Jansen Suze A, Cutilli Alessandro, de Koning Coco, van Hoesel Marliek, Sierra Leire Saiz, Nierkens Stefan, Mokry Michal, Nieuwenhuis Edward E S, Hanash Alan M, Mocholi Enric, Coffer Paul J, Lindemans Caroline A 30 Apr 2023,

Neurodegenerative disease after hematopoietic stem cell transplantation in metachromatic leukodystrophy

Al-Saady Murtadha, Beerepoot Shanice, Plug Bonnie C., Breur Marjolein, Galabova Hristina, Pouwels Petra J.W., Boelens Jaap Jan, Lindemans Caroline, van Hasselt Peter M., Matzner Ulrich, Vanderver Adeline, Bugiani Marianna, van der Knaap Marjo S., Wolf Nicole I. 2023, In: Annals of Clinical and Translational Neurology. 10 , p. 1146-1159 14 p.

Naive T Cells in Graft Versus Host Disease and Graft Versus Leukemia:Innocent or Guilty?

Dekker Linde, Sanders Evy, Lindemans Caroline A., de Koning Coco, Nierkens Stefan 20 Jun 2022, In: Frontiers in Immunology. 13 , p. 1-10

Fludarabine exposure predicts outcome after CD19 CAR T-cell therapy in children and young adults with acute leukemia

Dekker Linde, Calkoen Friso G., Jiang Yilin, Blok Hilly, Veldkamp Saskia R., De Koning Coco, Spoon Maike, Admiraal Rick, Hoogerbrugge Peter, Vormoor Britta, Vormoor H. Josef, Visscher Henk, Bierings Marc, Van Der Vlugt Marieke, Van Tinteren Harm, Nijstad A. Laura, Huitema Alwin D.R., Van Der Elst Kim C.M., Pieters Rob, Lindemans Caroline A., Nierkens Stefan 12 Apr 2022, In: Blood Advances. 6 , p. 1969-1976 8 p.

Challenges and opportunities targeting mechanisms of epithelial injury and recovery in acute intestinal graft-versus-host disease

Jansen Suze A, Nieuwenhuis Edward E S, Hanash Alan M, Lindemans Caroline A Apr 2022, In: Mucosal immunology. 15 , p. 605-619 15 p.

Clofarabine-fludarabine-busulfan in HCT for pediatric leukemia:an effective, low toxicity, TBI-free conditioning regimen

Versluijs A. Birgitta, de Koning Coco C.H., Lankester Arjan C., Nierkens Stefan, Kollen Wouter J., Bresters Dorine, Lindemans Caroline A., Boelens Jaap Jan, Bierings Marc 22 Mar 2022, In: Blood Advances. 6 , p. 1719-1730 12 p.

All research output

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