prof. dr. ir. J. Malda

Full Professor

  • Department of Orthopaedics
  • Department of Orthopaedics

prof. dr. ir. J. Malda


  1. Our research group focuses on biofabrication and biomaterials design, in particular for the regeneration of (osteo) chondral defects. We are developing novel biofabriaction strategies, as well and “bioinks” for 3D printing. These hydrogel-based “inks” are both designed to drive specific differentiation of the embedded and/or endogenous cells, as well as to allow fabrication with high shape fidelity in order to generate constructs that are a blueprint of the real tissue. In addition, we are adopting bioreactor technology to mature the generated tissue constructs. Finally, approaches towards the translation of the constructs in veterinary (equine) and human clinics are pursued, including its use as an in vitro platform for testing. 

    Areas of interest 
    - Joint regeneration 
    - Biofabrication 

    - Biomaterial development

    - Bioreactors

    - Extracellular matrix-derived scaffolds 

    - Nutrient limitation 

Side Activities

  • International Society for Biofabrication (ISBF), President

    International Cartilage Repair Society (ICRS), General Board member, Fellow member and Chair of Basic Science Committee

  • Professor of Biofabrication in Translational Regenerative Medicine (0.3FTE), Department of Equine Sciences, Utrecht University

    Former President of the International Society for Biofabrication (ISBF)

    Co-chair of the international Conference on Biofabrication 2015

Fellowship and Awards

Research Output (152)

Combining multi-scale 3D printing technologies to engineer reinforced hydrogel-ceramic interfaces

Diloksumpan Paweena, de Ruijter Mylène, Castilho Miguel, Gbureck Uwe, Vermonden Tina, van Weeren P René, Malda Jos, Levato Riccardo apr 2020, In: Biofabrication. 12 16 p.

Long-Term in Vivo Performance of Low-Temperature 3D-Printed Bioceramics in an Equine Model

Bolaños Rafael Vindas, Castilho Miguel, De Grauw Janny, Cokelaere Stefan, Plomp Saskia, Groll Jürgen, Van Weeren P. René, Gbureck Uwe, Malda Jos 9 mrt 2020, In: ACS Biomaterials Science and Engineering. 6 , p. 1681-1689 9 p.

Gel casting as an approach for tissue engineering of multilayered tubular structures

van Velthoven Melissa J J, Ramadan Rana, Zügel Franziska S, Klotz Barbara J, Gawlitta Debby, Costa Pedro F, Malda Jos, Castilho Miguel, de Kort Laetitia M O, de Graaf Petra 23 feb 2020, In: Tissue engineering. Part C, Methods. 26 , p. 190-198 9 p.

Fiber Scaffold Patterning for Mending Hearts:3D Organization Bringing the Next Step

Kristen Marleen, Ainsworth Madison J., Chirico Nino, van der Ven Casper F.T., Doevendans Pieter A., Sluijter Joost P.G., Malda Jos, van Mil Alain, Castilho Miguel 11 okt 2019, In: Advanced Healthcare Materials. 9 21 p.

Organs by design:Can bioprinting meet self-organization?

Martin Ivan, Malda Jos, Rivron Nicolas C. 1 okt 2019, In: Current Opinion in Organ Transplantation. 24 , p. 562-567 6 p.

Rethinking articular cartilage regeneration based on a 250-year-old statement

Malda Jos, Groll Jürgen, van Weeren P. René okt 2019, In: Nature Reviews Rheumatology. 15 , p. 571-572 2 p.

Volumetric Bioprinting of Complex Living-Tissue Constructs within Seconds

Bernal Paulina Nuñez, Delrot Paul, Loterie Damien, Li Yang, Malda Jos, Moser Christophe, Levato Riccardo okt 2019, In: Advanced materials. 31

A Versatile Biosynthetic Hydrogel Platform for Engineering of Tissue Analogues

Klotz Barbara J, Oosterhoff Loes A, Utomo Lizette, Lim Khoon S, Vallmajo-Martin Queralt, Clevers Hans, Woodfield Tim B F, Rosenberg Antoine J W P, Malda Jos, Ehrbar Martin, Spee Bart, Gawlitta Debby 12 aug 2019, In: Advanced Healthcare Materials. 8

Effects of body mass on microstructural features of the osteochondral unit:A comparative analysis of 37 mammalian species

Mancini I A D, Rieppo L, Pouran B, Afara I O, Braganca F M Serra, van Rijen M H P, Kik M, Weinans H, Toyras J, van Weeren P R, Malda J 3 jul 2019, In: Bone. 127 , p. 664-673 10 p.

T2* and quantitative susceptibility mapping in an equine model of post-traumatic osteoarthritis:assessment of mechanical and structural properties of articular cartilage

Nykänen Olli, Sarin Jaakko K, Ketola Juuso H, Leskinen Henri, Te Moller Nikae C R, Tiitu Virpi, Mancini Irina A D, Visser Jetze, Brommer Harold, René van Weeren P, Malda Jos, Töyräs Juha, Nissi Mikko J 2 jul 2019, In: Osteoarthritis and Cartilage. 27 , p. 1481-1490 10 p.

All Research Output (152)