prof. dr. ir. J. Malda

Full Professor
prof. dr. ir. J. Malda
  • Department of Orthopaedics
  • Department of Orthopaedics



  1. Our research group focuses on biofabrication and biomaterials design, in particular for the regeneration of (osteo) chondral defects. We are developing novel biofabriaction strategies, as well and “bioinks” for 3D printing. These hydrogel-based “inks” are both designed to drive specific differentiation of the embedded and/or endogenous cells, as well as to allow fabrication with high shape fidelity in order to generate constructs that are a blueprint of the real tissue. In addition, we are adopting bioreactor technology to mature the generated tissue constructs. Finally, approaches towards the translation of the constructs in veterinary (equine) and human clinics are pursued, including its use as an in vitro platform for testing. 

    Areas of interest 
    - Joint regeneration 
    - Biofabrication 

    - Biomaterial development

    - Bioreactors

    - Extracellular matrix-derived scaffolds 

    - Nutrient limitation 

Side Activities

International Society for Biofabrication (ISBF), President

International Cartilage Repair Society (ICRS), General Board member, Fellow member and Chair of Basic Science Committee

Professor of Biofabrication in Translational Regenerative Medicine (0.3FTE), Department of Equine Sciences, Utrecht University

Former President of the International Society for Biofabrication (ISBF)

Co-chair of the international Conference on Biofabrication 2015

Fellowship and Awards

Anna Prize 2017, Anna Foundation and Nederlandse Orthopaedische Vereniging

Nanonica Prize 2015 for the breakthrough of the year in the field of nanotechnology, Nanonica Europe

ERC Consolidator Grant ERC-2014-CoG_647426

NWO Veni FellowshipPrinten van levend kraakbeen 

Research Output (192)

Topographic features of nano-pores within the osteochondral interface and their effects on transport properties –a 3D imaging and modeling study

Pouran Behdad, Raoof Amir, de Winter D. A.Matthijs, Arbabi Vahid, Bleys Ronald L.A.W., Beekman Frederik J., Zadpoor Amir A., Malda Jos, Weinans Harrie 23 jun 2021, In: Journal of Biomechanics. 123 8 p.

Dual-contrast computed tomography enables detection of equine posttraumatic osteoarthritis in vitro

Saukko Annina E A, Sarin Jaakko K, Nykänen Olli, Nissi Mikko J, Te Moller Nikae C R, Weinans Harrie, Mancini Irina A D, Visser Jetze, Brommer Harold, van Weeren P Réné, Malda Jos, Grinstaff Mark W, Töyräs Juha 12 mei 2021, In: Journal of Orthopaedic Research.

Hydrogel-Based Bioinks for Cell Electrowriting of Well-Organized Living Structures with Micrometer-Scale Resolution

Castilho Miguel, Levato Riccardo, Bernal Paulina Nunez, de Ruijter Mylène, Sheng Christina Y, van Duijn Joost, Piluso Susanna, Ito Keita, Malda Jos 8 feb 2021, In: Biomacromolecules. 22 , p. 855-866 12 p.

Topographic Guidance in Melt-Electrowritten Tubular Scaffolds Enhances Engineered Kidney Tubule Performance

van Genderen Anne Metje, Jansen Katja, Kristen Marleen, van Duijn Joost, Li Yang, Schuurmans Carl C L, Malda Jos, Vermonden Tina, Jansen Jitske, Masereeuw Rosalinde, Castilho Miguel 18 jan 2021, In: Frontiers in bioengineering and biotechnology. 8 14 p.

Anisotropic hygro-expansion in hydrogel fibers owing to uniting 3D electrowriting and supramolecular polymer assembly

Wu Dan Jing, Vonk Niels H., Lamers Brigitte A.G., Castilho Miguel, Malda Jos, Hoefnagels Johan P.M., Dankers Patricia Y.W. 5 dec 2020, In: European polymer journal. 141

Rapid Photocrosslinking of Silk Hydrogels with High Cell Density and Enhanced Shape Fidelity:Rapid Photocrosslinking of Silk Hydrogels with High Cell Density and Enhanced Shape Fidelity (Adv. Healthcare Mater, (2020), 9, (1901667), 10.1002/adhm.201901667)

Cui Xiaolin, Soliman Bram G., Alcala-Orozco Cesar R., Li Jun, Vis Michelle A.M., Santos Miguel, Wise Steven G., Levato Riccardo, Malda Jos, Woodfield Tim B.F., Rnjak-Kovacina Jelena, Lim Khoon S. 18 nov 2020, In: Advanced Healthcare Materials. 9 , p. 1-1

Stable and Antibacterial Magnesium-Graphene Nanocomposite-Based Implants for Bone Repair

Safari Narges, Golafshan Nasim, Kharaziha Mahshid, Toroghinejad Mohammad Reza, Utomo Lizette, Malda Jos, Castilho Miguel 9 nov 2020, In: ACS Biomaterials Science and Engineering. 6 , p. 6253-6262 10 p.

Rapid and cytocompatible cell-laden silk hydrogel formation via riboflavin-mediated crosslinking

Piluso Susanna, Flores Gomez Daniela, Dokter Inge, Moreira Texeira Liliana, Li Yang, Leijten Jeroen, van Weeren René, Vermonden Tina, Karperien Marcel, Malda Jos 7 nov 2020, In: Journal of Materials Chemistry B. 8 , p. 9566-9575 10 p.

Impact of Endotoxins in Gelatine Hydrogels on Chondrogenic Differentiation and Inflammatory Cytokine Secretion In Vitro

Groen Wilhelmina M G A C, Utomo Lizette, Castilho Miguel, Gawlitta Debby, Malda Jos, Weeren P René van, Levato Riccardo, Korthagen Nicoline M 2 nov 2020, In: International journal of molecular sciences. 21 , p. 1-17 17 p.

Innovative Tissue-Engineered Strategies for Osteochondral Defect Repair and Regeneration:Current Progress and Challenges

Zhou Liangbin, Gjvm Van Osch, Malda Jos, Stoddart Martin J., Lai Yuxiao, Richards R. Geoff, Ki-wai Ho Kevin, Qin Ling 26 okt 2020, In: Advanced Healthcare Materials. 9

All research output

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