prof. dr. M.C. (Marianne C.) Verhaar
- Nephrology
Research Programs
Biography
Biography
The research of Marianne Verhaar focuses on renal and vascular regeneration and involves translational studies from basic cell studies to animal experiments and clinical trials. Het general aim is to improve care for the patient with chronic kidney disease by developing new strategies to enhance protective mechanisms against microvascular dysfunction, atherosclerotic disease and chronic kidney disease, to enhance vascular and renal regeneration and to improve renal replacement therapies. Specific interests of her group are: mechanisms underlying increased cardiovascular risk in chronic kidney disease, the realation between chronic kidney disease, microvascular dysfunction and heart failure, the role of (bone marrow-derived) stem and progenitor cells or cellular products in vascular and renal regeneration and their therapeutic potential in patients with cardiovascular and chronic kidney disease; development of renal organoids and search for renal stem cells using specific stem cell markers; investigate the potential of induced pluripotent stem cells for renal regeneration; development of a wearable artificial kidney.
Side Activities
Expert panel – The scientific challenge “Lab-Grown Organ Replacement “German Federal Ministry of Education and Research (BMBF) 2019-
Scientific board Dutch Kidney Foundation 2019-
European Renal Association – European Dialysis and Transplant Association (ERA-EDTA) Continuous Education and Professional Development (CEPD) Committee (Chair) 2019-
ERA-EDTA Scientific Advisory Board 2019-
ERA-EDTA EUropean REnal and CArdiovascular Medicine (EURECA-m) Working Group 2015-2019
Scientific Committee of the ERA-EDTA Berlin Meeting 2021
Scientific Committee of the ERA-EDTA Milan Meeting 2020
French National Research Agency (ANR) University Hospital institute Selection Committee (Chair) 2017-
Scientific Forum of the Netherlands Heart Institute 2016-
Science Europe Scientific Advisory Committee 2015-2018
ZonMw Programme Committee Innovational Research Incentives Scheme Veni 2010-2018
NWO Innovational Research Incentives Scheme Vidi (interdivisional) 2014
ZonMw Programme Committee Translational Research 2010-2020
International Review Board Academy of Finland, 2011 & 2015
Review Committee Regenerative Medicine proposals European Committee, 2009
Visiting professor at Renal Research Institute, New York Medical College, department of Nephrology (Prof. dr. M.S. Goligorsky) (2009)
Fellowship and Awards
NWO Vidi & ASPASIA grant (2008)
NWO Veni grant (2002)
Jaarprijs Vasculaire Biologie, Nederlandse Vereniging voor Cardiologie (1998)
Research Output (292)
van Gelder Maaike K, de Vries Joost C, Simonis Frank, Monninkhof Anneke S, Hazenbrink Diënty H M, Ligabue Giulia, Giovanella Silvia, Joles Jaap A, Verhaar Marianne C, Bajo Rubio Maria A, Selgas Rafael, Cappelli Gianni, Gerritsen Karin G F dec 2020, In: Physiological Reports [E]. 8 14 p.
Jansz Thijs T, Özyilmaz Akin, van Reekum Franka E, Boereboom Franciscus T J, de Jong Pim A, Verhaar Marianne C, van Jaarsveld Brigit C dec 2020, In: PLoS ONE. 15 , p. 1-12 12 p.
van Eck van der Sluijs Anita, Abrahams Alferso C, Rookmaaker Maarten B, Verhaar Marianne C, Bos Willem Jan W, Blankestijn Peter J, Dekker Friedo W, van Diepen Merel, Ocak Gurbey 1 nov 2020, In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 36 , p. 170-175 6 p.
Hornung Paul, Khairoun Meriem, Dekker Friedo W, Kaasjager Karin A H, Huisman Albert, Jakulj Lily, Bos Willem Jan W, Rosendaal Frits R, Verhaar Marianne C, Ocak Gurbey 1 okt 2020, In: PLoS ONE. 15 , p. 1-14
Krebber Merle M, van Dijk Christian G M, Vernooij Robin W M, Brandt Maarten M, Emter Craig A, Rau Christoph D, Fledderus Joost O, Duncker Dirk J, Verhaar Marianne C, Cheng Caroline, Joles Jaap A 14 sep 2020, In: International journal of molecular sciences. 21 , p. 1-22 22 p.
Pei Jiayi, Harakalova Magdalena, Treibel Thomas A, Lumbers R Thomas, Boukens Bastiaan J, Efimov Igor R, van Dinter Jip T, González Arantxa, López Begoña, El Azzouzi Hamid, van den Dungen Noortje, van Dijk Christian G M, Krebber Merle M, den Ruijter Hester M, Pasterkamp Gerard, Duncker Dirk J, Nieuwenhuis Edward E S, de Weger Roel, Huibers Manon M, Vink Aryan, Moore Jason H, Moon James C, Verhaar Marianne C, Kararigas Georgios, Mokry Michal, Asselbergs Folkert W, Cheng Caroline 14 jul 2020, In: Clinical Epigenetics. 12 18 p.
Mihaila Silvia M, Faria João, Stefens Maurice F J, Stamatialis Dimitrios, Verhaar Marianne C, Gerritsen Karin G F, Masereeuw Rosalinde 12 jun 2020, In: Toxins. 12 16 p.
Yousef Yengej Fjodor A, Jansen Jitske, Rookmaaker Maarten B, Verhaar Marianne C, Clevers Hans jun 2020, In: Cells. 9 20 p.
van Dijk Christian G M, Louzao-Martinez Laura, van Mulligen Elise, Boermans Bart, Demmers Jeroen A A, van den Bosch Thierry P P, Goumans Marie-José, Duncker Dirk J, Verhaar Marianne C, Cheng Caroline jun 2020, In: International journal of molecular sciences. 21 18 p.
Pieters Tobias T, Beele Paul, Van Zuilen Arjan D, Verhaar Marianne C, Huitema Alwin D R, Rookmaaker Maarten B 8 mei 2020, In: Clinical Pharmacokinetics. 59 , p. 1303-1311 9 p.