prof. dr. ir. H.H. (Harrie) Weinans

prof. dr. ir. H.H. (Harrie) Weinans

Associate Professor
prof. dr. ir. H.H. (Harrie) Weinans



Our stiff bones are held together by ligaments and tendons and carry the weight and transfer the large forces that are required for locomotion. Without these load bearing mechanical tissues we would look like a gelatin pudding. With aging or after trauma the delicate internal architecture of these connective tissues gets lost, which can result in e.g. cartilage damage and subsequent deterioration (osteoarthritis), loss of bone mass (osteoporosis) problematic healing of fractures or tendons. Bone and cartilage are load bearing structures and degeneration and regeneration in these tissues are continuously influenced by and adapted to the biomechanical demands. The major goal of my research is to investigate the degenerative processes in the skeletal structures and find methods to counterbalance this degeneration or even induce appropriate regeneration after the tissue is already diminished.

Harrie Weinans is minority shareholder of Uplanner BV and Replasia BV

Research Output (244)

Trained innate immunity modulates osteoblast and osteoclast differentiation

Rahmani N R, Belluomo R, Kruyt M C, Gawlitta D, Joosten L A B, Weinans H, Croes M 13 Mar 2024, In: Stem cell reviews and reports. 20 , p. 1121-1134 14 p.

Photoimmuno-antimicrobial therapy for Staphylococcus aureus implant infection

Dijk Bruce van, Oliveira Sabrina, Hooning van Duyvenbode J Fred F, Nurmohamed F Ruben H A, Mashayekhi Vida, Hernández Irati Beltrán, van Strijp Jos, de Vor Lisanne, Aerts Piet C, Vogely H Charles, Weinans Harrie, van der Wal Bart C H Mar 2024, In: PLoS ONE. 19 10 p.

Radiologic Assessment of Interbody Fusion:A Systematic Review on the Use, Reliability, and Accuracy of Current Fusion Criteria

Duits Anneli A A, van Urk Paul R, Lehr A Mechteld, Nutzinger Don, Reijnders Maarten R L, Weinans Harrie, Foppen Wouter, Oner F Cuhmur, van Gaalen Steven M, Kruyt Moyo C 9 Jan 2024, In: JBJS reviews. 12 , p. 1-11 11 p.

Mesenchymal stem/stromal cells-derived extracellular vesicles as a potentially more beneficial therapeutic strategy than MSC-based treatment in a mild metabolic osteoarthritis model

Warmink Kelly, Rios Jaqueline L., Varderidou-Minasian Suzy, Torres-Torrillas Marta, van Valkengoed Devin R., Versteeg Sabine, Eijkelkamp Niels, Weinans Harrie, Korthagen Nicoline M., Lorenowicz Magdalena J. Dec 2023, In: Stem Cell Research and Therapy. 14

Development and validation of a machine learning-supported strategy of patient selection for osteoarthritis clinical trials:the IMI-APPROACH study

Widera Paweł, Welsing Paco M.J., Danso Samuel O., Peelen Sjaak, Kloppenburg Margreet, Loef Marieke, Marijnissen Anne C., van Helvoort Eefje M., Blanco Francisco J., Magalhães Joana, Berenbaum Francis, Haugen Ida K., Bay-Jensen Anne Christine, Mobasheri Ali, Ladel Christoph, Loughlin John, Lafeber Floris P.J.G., Lalande Agnès, Larkin Jonathan, Weinans Harrie, Bacardit Jaume Dec 2023, In: Osteoarthritis and Cartilage Open. 5

3D printed and punched porous surfaces of a non-resorbable, biphasic implant for the repair of osteochondral lesions improves repair tissue adherence and ingrowth

Fugazzola Maria C., Golafshan Nasim, van Aken Joris A., Plomp Saskia, De Grauw Janny, van Buul Ward, Hermsen Gied, Weinans Harrie, Castilho Miguel, van Weeren René, Malda Jos Nov 2023, In: Pferdeheilkunde. 39 , p. 504-514 11 p.

Unravelling the hip-spine dilemma from the CHECK-cohort:is sagittal pelvic morphology linked to radiographic signs of femoroacetabular impingement?

van Erp Joost H.J., Gielis Willem Paul, Arbabi Vahid, de Gast Arthur, Weinans Harrie, Kaas Laurens, Castelein René M., Schlösser Tom P.C. Nov 2023, In: HIP International. 33 , p. 1079-1085 7 p.

Microencapsulated stem cells reduce cartilage damage in a material dependent manner following minimally invasive intra-articular injection in an OA rat model

Johnbosco Castro, Karbaat Lisanne, Korthagen Nicoline M, Warmink Kelly, Koerselman Michelle, Coeleveld Katja, Becker Malin, van Loo Bas, Zoetebier Bram, Both Sanne, Weinans Harrie, Karperien Marcel, Leijten Jeroen Oct 2023, In: Materials Today Bio. 22 12 p.

Antibacterial CATH-2 Peptide Coating to Prevent Bone Implant-Related Infection

Keikhosravani Pardis, Jahanmard Fatemeh, Bollen Tim, Nazmi Kamran, Veldhuizen Edwin J.A., Gonugunta Prasad, Anusuyadevi Prasaanth Ravi, van der Wal Bart C.H., Vogely Charles, Bikker Floris J., Taheri Peyman, Weinans Harrie, Amin Yavari Saber 25 Sep 2023, In: Advanced Materials Technologies. 8 , p. 1-13 13 p.

Evaluation of silver bio-functionality in a multicellular in vitro model:towards reduced animal usage in implant-associated infection research

Cecotto Leonardo, Stapels Daphne A.C., van Kessel Kok P.M., Croes Michiel, Lourens Zeldali, Vogely H. Charles, van der Wal Bart C.H., van Strijp Jos A.G., Weinans Harrie, Amin Yavari Saber 5 Jun 2023, In: Frontiers in cellular and infection microbiology. 13 , p. 1-13 13 p.

All research output

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