prof. dr. R. (Richard) van Hillegersberg Full Professor

Contact

Research programs

Cancer

Biography
Side Activities
Research Output
Fellowship and Awards

Biography

Richard van Hillegersberg attended medical school in Rotterdam, the Netherlands. In 1990 he received a research grant from the Dutch Digestive Foundation, that enabled him to perform PhD research on the local treatment of liver metastases at the Department of Surgery, Erasmus MC in Rotterdam. In 1993 he received his PhD with honor. After obtaining his MD in 1994, he was a resident of Surgery in Rotterdam and was registered as general surgeon in 2000. From 2001-2002 he was a fellow of Surgical Oncology in the Academic Medical Center and Antoni van Leeuwenhoek Netherlands Cancer Center Amsterdam. Since 2003 he is appointed as staff surgeon at the University Medical Center Utrecht. From 2009 he is a full professor of gastrointestinal oncology and program leader of the GI-Oncology department. His clinical interests are upper gastrointestinal tract and hepatobiliary surgery. Research is focused on minimally invasive and robotic surgery, surgical imaging, genetic profiling and radiofrequency ablation for cancer. He has authored and co-authored over 200 articles in international peer-reviewed journals. He is past president of the Dutch GI Surgical Association, past board member of the Dutch Surgical Association, board member of the Dutch Society for liver surgery, president of the European Digestive Surgery, Chairman Dutch Upper GI Surgery Working Group and member of the permanent Scientific committee OESO World Organisation for Specialised studies on diseases of the esophagus.

Side Activities

Committee, board, editorial

2005 Board Member and Secretary of the Dutch Liver Surgery working group

2006 Editor of "Oncollectie"; News Facts on oncology and hematology

2009 Council member European Digestive Surgery

2009 Member Committee Dutch Guidelines oesophageal cancer, IKNL

2011 Board Member DUCA (Dutch UpperGI Cancer Audit)

2012 Editorial Board Member Journal of Gastroenterology and Hepatology Reasearch

2012 Scientific Advisory Committee MLD Stichting – Career Development Grant

2012 Chairman of MIRA special committee on robotic esophageal surgery

2013 Chairman Dutch Upper GI Surgery Working Group

2014 Board Member permanent Scientific committee OESO World Organisation for Specialised studies on diseases of the esophagus

2014 Board Member Technogolgy committee European Association for Endoscopic Surgery

2014 Editorial Board member Digestive Surgery

2015 EDS president elect. European Digestive Surgery

Visiting Professor Candiolo Institute Turin, 1 Jan 2019 → …

Proctor Intuitive Surgical, 1 Jan 2009 → …

Research Output

Do esophageal cancer survivors work after esophagectomy and do health problems impact their work? A cross-sectional study

Kingma B. F., Rauwerdink P., Brenkman H. J.F., Ruurda J. P., van Hillegersberg R. 17 Dec 2019 In: Journal of Cancer Survivorship.

Nationwide Outcome of Gastrectomy with En-Bloc Partial Pancreatectomy for Gastric Cancer

van der Werf L. R., Eshuis W. J., Draaisma W. A., van Etten B., Gisbertz S. S., van der Harst E., Liem M. S.L., Lemmens V. E.P.P., Wijnhoven B. P.L., Besselink M. G., van Berge Henegouwen M. I., van Hillegersberg R., van Eijden Y., van Esser S., Hartgrink H. H., de Jong G., Karsten T. M., Kouwenhoven E. A., Lagarde S. M., Nieuwenhuijzen G. A.P., van der Peet D. L., van Sandick J. W., Talsma A. K., Tetteroo G. W.M., 1 Dec 2019 In: Journal of Gastrointestinal Surgery. 23, p. 2327-2337 11 p.

Restaging after chemoradiotherapy for locally advanced esophageal cancer

Defize Ingmar L., van Hillegersberg Richard, Mook Stella, Meijer Gert J., Lin Steven H., Ruurda Jelle P., van Rossum Peter S. N. Dec 2019 In: Annals of Translational Medicine. 7

Erratum: Resection of hepatic and pulmonary metastasis from metastatic esophageal and gastric cancer: A nationwide study (Diseases of the Esophagus (doz034) DOI: 10.1093/dote/doz034)

Seesing M. F.J., Van Der Veen A., Brenkman H. J.F., Stockmann H. B.A.C., Nieuwenhuijzen G. A.P., Rosman C., Van Den Wildenberg F. J.H., Van Berge Henegouwen M. I., Van Duijvendijk P., Wijnhoven B. P.L., Stoot J. H.M.B., Lacle M., Ruurda J. P., Van Hillegersberg R. 13 Nov 2019 In: Diseases of the Esophagus. 32

Safety of radiofrequency ablation in patients with locally advanced, unresectable pancreatic cancer: A phase II study

Fegrachi Samira, Walma Marieke S., de Vries Jan J.J., van Santvoort Hjalmar C., Besselink Marc G., von Asmuth Erik G., van Leeuwen Maarten S., Borel Rinkes Inne H., Bruijnen Rutger C., de Hingh Ignace H., Klaase Joost M., Molenaar I. Quintus, van Hillegersberg Richard 1 Nov 2019 In: European Journal of Surgical Oncology. 45, p. 2166-2172 7 p.

International Variation in Surgical Practices in Units Performing Oesophagectomy for Oesophageal Cancer: A Unit Survey from the Oesophago-Gastric Anastomosis Audit (OGAA)

Bundred James R., Kamarajah Sivesh K., Siaw-Acheampong Kobby, Nepogodiev Dmitri, Jefferies Benjamin, Singh Pritam, Evans Richard, Griffiths Ewen A., Alderson Derek, Gossage James, McKay Siobhan, Mohamed Imran, van Hillegersberg Richard, Vohra Ravinder, Wanigsooriya Kasun, Whitehouse Tony, Bagajevas Aleksandras, Bekele Abebe, Blanco-Colino Ruth, Da Roit Anna, El Kafsi-Mawley Jihene, Gjata Arben, Gockel Ines, Castro Raul Guevara, Harustiak Tomas, Hsu Po Kuei, Isik Arda, Kechagias Aristotelis, Kennedy Andrew, Kidane Biniam, Mahendran Hans Alexander, Mejia Loreli, Moreno Jorge Ignacio, Negoi Ionut, Santiago Azagra Juan, Sayyed Raza, Schneider Paul, Soares António Sampaio, Sousa Mariana, Takeda Flavio Roberto, Vanstraten Stephanie, Wallner Bengt, Wijnhoven Bas, Achiam Michael, Agustin Tita, Akbar Ali, Al-Bahrani Ahmad, Al-Khyatt Waleed, Albertsmeier Markus, Alghunaim Essa, 1 Nov 2019 In: World Journal of Surgery. 43, p. 2874-2884 11 p.

Machine Learning to predict early recurrence after oesophageal cancer surgery

Rahman Saqib, Walker Robert, Lloyd Megan, Grace Ben, van Boxel Gijs, Kingma B. Feike, Ruurda Jelle, van Hillegersberg Richard, Harris Scott, Parsons Simon, Mercer Stuart, Griffiths Ewen, O'Neill J. Robert, Turkington Richard, Fitzgerald Rebecca, Underwood Timothy Nov 2019 In: British Journal of Surgery. 106, p. 12-12

Abstracts of the Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland, 22nd AUGIS Annual Meeting 25-27 September 2019, ACC Conference Centre, Liverpool

Markar Sheraz, Lagergren Pernilla, Zaninotto Giovanni, Huddy Jeremy, Findlay John, Antonowicz Stefan, Maynard Nick, Ariyathenam Arun, Sanders Grant, Jahoo Shameen, McCormack Orla, Allum William, Klevebro Fredrik, Nilsson Magnus, Henegouwen Mark Van Berge, Gisbertz Suzanne, Van Hillegersberg Richard, Ruurda Jelle, Lagarde Sjoerd, Wijnhoven Bas, Elliott Jessie, Van Lanschot Jan, Matthijsen Robert, Pera Manuel, Alferi Rita, Castoro Carlo, Reynolds John, Hanna George Nov 2019 In: British Journal of Surgery. 106, p. 5-94 90 p.

Prophylactic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Gastric Cancer-A Systematic Review

Brenkman H J F, Päeva M, van Hillegersberg R, Ruurda J P, Haj Mohammad N 15 Oct 2019 In: Journal of Clinical medicine. 8

Liver Resection for Hepatic Metastases from Soft Tissue Sarcoma: A Nationwide Study

Grimme Frederike A.B., Seesing Maarten F.J., Van Hillegersberg Richard, Van Coevorden Frits, De Jong Koert P., Nagtegaal Iris D., Verhoef Cornelis, De Wilt Johannes H.W. 1 Oct 2019 In: Digestive Surgery. 36, p. 479-486 8 p.

All Research Output (338)

Fellowship and Awards

1990-1992Principal investigator. Treatment of liver meatstases with laser, Erasmus University Rotterdam. Project leader. Nederlandse Lever Darm Stichting (NLDS); WS 89-14. Eu 120.000
1996-1998 Principal investigator. Ablation of Barrett'se oesophagus with photodynamic therapy after 5-aminolevulinic acid. Erasmus University Rotterdam. Nederlandse Lever Darm Stichting (NLDS); WS 95-10. Eu 120.000
1995-1998 Principal investigator. Interstital lasercoagulation for liver metastases MRI thermography guided. Revolving Fund AZR. Eu 25.000
1996 Principal investigator. Short and long term outcome of interstitial laser coagulation with multiple fibers. Stichting Gastrostart. Eu 15.000
1998-2002 Principal investigator. Endovascular photodynamic therapy to prevent intimal hyperplasia after vascular interventions. Nederlandse Hartstichting (NHS) nr 97.181. Eu 250.000
2003-2007 Co-investigator. Is angiogenesis the key to more effective local treatment of liver metastases by interstitial thermal ablation? AGIKO project NWO. Eu 150.00
2003-2007 Co-investigator. Ischemia and reperfusion injury in the treatment of liver metastases. AGIKO project NWO. Eu 150.000
2003-2009 Co-investigator. Stategies to improve the outcome of esophagectomy in esophageal cancer. MDPhD project UMCU. Eu 120.000
2005-2009 Principal investigator. Local ablation of patients with T1 breast cancer. Unrestricted Grant Olympu. Eu 40.000
2005-2010 Principal investigator. Multicenter RCT HEPATICA studie. Hepatic resection followed by adjuvant treatment in colorectal liver metastases. Unrestricted Investigational grants van Sanofi-Aventis en Roche Eu 1.2000. CKTO KWF. WBSO subsidie(CX1T,2007). Eu 500.000
2006-2008 Principal investigator. RCT in Cytokine production related to desufflation of one lung in minimally invasive esophagectomy. IKMN bourse. Eu 20.000
2006-2011 Principal investigator. ZonW Multicenter gerandomiseerde trial “Radioguided occult lesion localisation in patients with non-palpable breast cancer. ZonMW en IKMN beurs (80-00702-98-037). Eu 383.000
2006-present Principal investigator. Optimalisatie van imaging focale lever laesies. Unrestricted Grant Beyer. Eu 120.000
2008-2009 Principal investigator. Esophagectomy: outcomes and perioperative course of esophageal cancer surgery. Unrestricted Grand Nycomed. Eu 20.000
2010–present Principal investigator. Radiofrequency ablation of locally advanced pancreatic cancer. NWO Mozaïek beurs. Eu 250.000
2011-present co-Principal investigator. Somatoststin for RFA of pancreatic cancer animal model studies. Unrestricted Grant Novartis. Eu 120.000
2012-present Principal investigator. Project non-colorectal liver metastases. NWO Mosaic beurs. Eu 250.000
2013-present Principal investigator. Radioembolization for Colorectal liver Metastases after Ablation. MDPhD Suerman program grant. Eu 100.000.
2014  European Society of Surgerical Oncology fellowship grant for fellow Aristoteles Kechagias, Greece, May 1,till July 1, 2014.
2014  Intuitive Surgery: Susanne van der Velden, fellow Robotchirurgie, Eu 75.000.
2014  Principal investigator. Cost effectiveness of laparoscopic gastrectomy as an alternative to open gastrectomy for gastric cancer. ZonMw (837002502) Eu 400.000