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prof. dr. ir. A. (Alexander) van Oudenaarden

Full Professor

  • Molecular Cancer Research
  • Hubrecht Institute

Research Programs

Research Output (104)

Snake Venom Gland Organoids

Post Yorick, Puschhof Jens, Beumer Joep, Kerkkamp Harald M., de Bakker Merijn A.G., Slagboom Julien, de Barbanson Buys, Wevers Nienke R., Spijkers Xandor M., Olivier Thomas, Kazandjian Taline D., Ainsworth Stuart, Iglesias Carmen Lopez, van de Wetering Willine J., Heinz Maria C., van Ineveld Ravian L., van Kleef Regina G.D.M., Begthel Harry, Korving Jeroen, Bar-Ephraim Yotam E., Getreuer Walter, Rios Anne C., Westerink Remco H.S., Snippert Hugo J.G., van Oudenaarden Alexander, Peters Peter J., Vonk Freek J., Kool Jeroen, Richardson Michael K., Casewell Nicholas R., Clevers Hans 23 jan 2020, In: Cell. 180 , p. 233-247.e21

Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids

van den Brink Susanne C., Alemany Anna, van Batenburg Vincent, Moris Naomi, Blotenburg Marloes, Vivié Judith, Baillie-Johnson Peter, Nichols Jennifer, Sonnen Katharina F., Martinez Arias Alfonso, van Oudenaarden Alexander 1 jan 2020, In: Nature. 582 , p. 405-409

Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion

Van Es Johan H., Wiebrands Kay, López-Iglesias Carmen, Van De Wetering Marc, Zeinstra Laura, Van Den Born Maaike, Korving Jeroen, Sasaki Nobuo, Peters Peter J., Van Oudenaarden Alexander, Clevers Hans 26 dec 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116 , p. 26599-26605 7 p.

Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart

Honkoop Hessel, de Bakker Dennis Em, Aharonov Alla, Kruse Fabian, Shakked Avraham, Nguyen Phong D, de Heus Cecilia, Garric Laurence, Muraro Mauro J, Shoffner Adam, Tessadori Federico, Peterson Joshua Craiger, Noort Wendy, Bertozzi Alberto, Weidinger Gilbert, Posthuma George, Grun Dominic, van der Laarse Willem J, Klumperman Judith, Jaspers Richard T, Poss Kenneth D, van Oudenaarden Alexander, Tzahor Eldad, Bakkers Jeroen 23 dec 2019, In: eLife. 8

Unravelling cellular relationships during development and regeneration using genetic lineage tracing

Baron Chloé S., van Oudenaarden Alexander 1 dec 2019, In: Nature reviews molecular cell biology. 20 , p. 753-765 13 p.

Cell Type Purification by Single-Cell Transcriptome-Trained Sorting

Baron Chloé S., Barve Aditya, Muraro Mauro J., van der Linden Reinier, Dharmadhikari Gitanjali, Lyubimova Anna, de Koning Eelco J.P., van Oudenaarden Alexander 3 okt 2019, In: Cell. 179 , p. 527-542.e19

Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration

Pepe-Mooney Brian J., Dill Michael T., Alemany Anna, Ordovas-Montanes Jose, Matsushita Yuki, Rao Anuradha, Sen Anushna, Miyazaki Makoto, Anakk Sayeepriyadarshini, Dawson Paul A., Ono Noriaki, Shalek Alex K., van Oudenaarden Alexander, Camargo Fernando D. 3 jul 2019, In: Cell Stem Cell. 25 , p. 23-38.e8

Spindle checkpoint silencing at kinetochores with submaximal microtubule occupancy

Etemad Banafsheh, Vertesy Abel, Kuijt Timo E.F., Sacristan Carlos, Van Oudenaarden Alexander, Kops Geert J.P.L. 17 jun 2019, In: Journal of Cell Science. 132 15 p.

A transcriptomic roadmap to α- and β-cell differentiation in the embryonic pancreas

van Gurp Léon, Muraro Mauro J., Dielen Tim, Seneby Lina, Dharmadhikari Gitanjali, Gradwohl Gerard, van Oudenaarden Alexander, de Koning Eelco J.P. 1 jun 2019, In: Development (Cambridge). 146

Oral mucosal organoids as a potential platform for personalized cancer therapy

Driehuis Else, Kolders Sigrid, Spelier Sacha, Lõhmussaar Kadi, Willems Stefan M., Devriese Lot A., de Bree Remco, de Ruiter Emma J., Korving Jeroen, Begthel Harry, van Es Johan H., Geurts Veerle, He Gui Wei, van Jaarsveld Richard H., Oka Rurika, Muraro Mauro J., Vivié Judith, Zandvliet Maurice M.J.M., Hendrickx Antoni P.A., Iakobachvili Nino, Sridevi Priya, Kranenburg Onno, van Boxtel Ruben, Kops Geert J.P.L., Tuveson David A., Peters Peter J., van Oudenaarden Alexander, Clevers Hans 3 mei 2019, In: Cancer Discovery. 9 , p. 852-871 20 p.

All Research Output (104)