dr. N.M. (Nina) van Sorge Associate Professor

Department of Medical Microbiology

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Infection & Immunity

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Research Output

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects

van Hensbergen Vincent P, Movert Elin, de Maat Vincent, Lüchtenborg Christian, Le Breton Yoann, Lambeau Gérard, Payré Christine, Henningham Anna, Nizet Victor, van Strijp Jos A G, Brügger Britta, Carlsson Fredric, McIver Kevin S, van Sorge Nina M 15 Oct 2018 In: PLoS Pathogens. 14

Group IIA-secreted phospholipase A₂ in human serum kills commensal but not clinical Enterococcus faecium isolates

Paganelli Fernanda L., Leavis Helen L., He Samantha, van Sorge Nina M., Payré Christine, Lambeau Gérard, Willems Rob J.L., Rooijakkers Suzan H.M. 1 Aug 2018 In: Infection and Immunity. 86

Defining Host Responses during Systemic Bacterial Infection through Construction of a Murine Organ Proteome Atlas

Lapek John D, Mills Robert H, Wozniak Jacob M, Campeau Anaamika, Fang Ronnie H, Wei Xiaoli, van de Groep Kirsten, Perez-Lopez Araceli, van Sorge Nina M, Raffatellu Manuela, Knight Rob, Zhang Liangfang, Gonzalez David J May 2018 In: Cell Systems. 6, p. 579-592.e4

Virulence role of the glcnac side chain of the lancefield cell wall carbohydrate antigen in non-m1-serotype group a streptococcus

Henningham Anna, Davies Mark R., Uchiyama Satoshi, Van Sorge Nina M., Lund Sean, Chen Kelsey T., Walker Mark J., Cole Jason N., Nizet Victor 1 Jan 2018 In: mBio. 9

Serine aspartate repeat protein D increases Staphylococcus aureus virulence and survival in blood

Askarian Fatemeh, Uchiyama Satoshi, Valderrama J. Andrés, Ajayi Clement, Sollid Johanna U E, van Sorge Nina M., Nizet Victor, van Strijp Jos A G, Johannessen Mona 2017 In: Infection and Immunity. 85

Bacterial Immune Evasion through Manipulation of Host Inhibitory Immune Signaling

Van Avondt Kristof, van Sorge Nina M., Meyaard Linde Mar 2015 In: PLoS Pathogens. 11 8 p.

Structural and functional insights into Group A Streptococcus gacA: An essential dTDP-4-dehydrorhamnose reductase (RmlD)

van der Beek Samantha L., Le Breton Yoann, Ferenbach Andrew T., van Aalten Daan M. F., Navratilova Iva, McIver Kevin, van Sorge Nina M., Dorfmueller Helge C. Nov 2014 In: Glycobiology. 24, p. 1126-1126 1 p.

Group B Streptococcus suppresses neutrophil function by engaging signal inhibitory receptor on leukocytes-1

van Avondt K., Nizet V., van Sorge N., Meyaard L. May 2014 In: European Journal of Clinical Investigation. 44, p. 37-37 1 p.

Genetics and virulence role of the classical group A Streptococcus Lancefield antigen

Cole Jason, van Sorge Nina, Kuipers Kirsten, Henningham Anna, Aziz Ramy, Kasirer-Friede Ana, Lin Leo, Berends Evelien, Davies Mark, Dougan Gordan, Zhang Fan, Dahesh Samira, Shaw Laura, Gin Jennifer, Cunningham Madeleine, Merriman Joseph, Rooijakkers Suzan, Malley Richard, Walker Mark, Shattil Sanford, Schlievert Patrick, Choudhury Biswa, Nizet Victor Apr 2014 In: FASEB Journal. 28 1 p.

A Staphylococcus aureus TIR domain protein virulence factor blocks TLR2-mediated NF-κB signaling

Askarian F., van Sorge N.M., Sangvik M., Beasley F.C., Henriksen J.R., Sollid J.U., van Strijp J.A.G., Nizet V., Johannessen M. 2014 In: Journal of Innate Immunity. 6, p. 485-498 14 p.

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