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Group Bont

About

The RSV Research Group has the vision to combine clinical and basic research to decrease the global burden of RSV infection. Our mission is to improve knowledge of RSV epidemiology, and to develop safe and effective therapeutic and preventive interventions. The RSV Research Group consists of clinician scientists and lab researchers focusing on the epidemiology and pathogenesis of RSV bronchiolitis. RSV infections cause a major burden for patients, their parents and society. RSV infection is the second most frequent cause of death during infancy, only malaria is associated with higher mortality.

Group members

Group Leaders

prof. dr. L.J. Bont Full Professor

Dr. Bont has regular interaction with pharmaceutical and other industrial partners. He has not received personal fees or other personal benefits. UMCU has received major funding (>€100,000 per industrial partner) for investigator initiated studies from AbbVie, MedImmune, Janssen, Pfizer, the Bill and Melinda Gates Foundation and MeMed Diagnostics. UMCU has received major cash or in kind funding as part of the public private partnership IMI-funded RESCEU project from GSK, Novavax, Janssen, AstraZeneca, Pfizer and Sanofi. UMCU has received major funding by Julius Clinical for participating in the INFORM study sponsored by MedImmune. UMCU has received minor funding for participation in trials by Regeneron and Janssen from 2015-2017 (total annual estimate less than €20,000). UMCU received minor funding for consultation and invited lectures by AbbVie, MedImmune, Ablynx, GSK, Bavaria Nordic, MabXience, Novavax, Pfizer, Janssen (total annual estimate less than €20,000). Dr. Bont is the founding chairman of the ReSViNET Foundation.

prof. dr. L. Meyaard Full Professor

Senior researchers

  • Joanne Wildenbeest
  • Katrien Oude Rengerink

Technician

  • Margreet Westerlaken

PhD students

  • Koos Korsten
  • Natalie Mazur
  • Sjanna Besteman
  • Arthur van Stigt
  • Annefleur Langedijk
  • Yvette Lowensteyn
  • Roy Zuurbier
  • Marie Billard

Patient advisory board

  • Nicole Derksen-Lazet, lead Patient Advisory Board
  • Inge Oliemans, communication Patient Advisory Board

Research nurses

  • Loes Nibbelke
  • Brigitte Buiteman

ReSViNET Foundation

Leyla Kragten-Tabatabaie, Board of Directors ReSViNET Foundation

Key publications

  1. Blanken, M. O., et al. (2013). "Respiratory Syncytial Virus and Recurrent Wheeze in Healthy Preterm Infants." 368(19): 1791-1799.Blanken, M. O., et al. (2013). View
  2. Mazur, N. I., et al. (2015). "Lower respiratory tract infection caused by respiratory syncytial virus: current management and new therapeutics." Lancet Respir Med 3(11): 888-900. View
  3. van Houten, C. B., et al. (2017). "A host-protein based assay to differentiate between bacterial and viral infections in preschool children (OPPORTUNITY): a double-blind, multicentre, validation study." Lancet Infect Dis 17(4): 431-440. View
  4. Scheltema, N. M., et al. (2018). "Respiratory syncytial virus prevention and asthma in healthy preterm infants: a randomised controlled trial." Lancet Respir Med 6(4): 257-264. View
  5. Mazur, N. I., et al. (2018). "The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates." Lancet Infect Dis 18(10): e295-e311. View

Marteen Blanken

2019

Chantal van Houten

2019

 Nienke Scheltema
2018

Innate immunity in RSV infection

Tina Faber

2017

Grants


2017 - Respiratory Syncitial virus Consortium in Europe(RESCUE, IMI)

2016 - RSV GOLD (BMGF)

2014 - Longfonds Consortium Grant

Support our research

  • Resvinet foundation

Collaborations

RSV GOLD

funded by Bill and Melinda Gates Foundation

IMPRIND

for biomarker research to diagnose bacterial infection

ReSViNET Network

for RSV Research, chairman

TAILORED Network

for biomarker discovery of virus versus bacterial respiratory tract infection

RESCEU Network

for RSV Burden of Disease studies (funded by IMI/H2020)

RSV Society

under ISIRV

Education & Courses

  • International conference: RSVVW, Accra, Ghana
  • Summer school on Global Child Health, Utrecht

Research programs

  • Infection and Immunity
  • Child Health

Research interests/topics

Epidemiology and pathogenesis of RSV bronchiolitis

Contact

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