dr. J. (Jacqueline) Alblas Associate Professor
- ORT Research
Jacqueline Alblas is PI bone regeneration at the department of Orthopaedics, University Medical Center Utrecht. She has wide experience in bone regenerative medicine, where the main focus is to develop hybrid constructs in which scaffold material and cell stimuli are optimally combined with the regenerative potential of adult stem cells. Important expertise is present with respect to tissue architecture, (neo)vascularization, gene delivery and immunological aspects of bone substitutes. The interaction of bone with the immune system is an important research theme, in particular with regard to the use of allogeneic cells. This is complemented by investigations of the influence of immune cells and inflammatory mediators on bone regeneration. Printing of living cells, which was developed in her group since 2005, is used to investigate the role of self-organisation of cells and matrix components in bone tissue repair and 3D printed constructs also act as model systems for bone-residing diseases, such as multiple myeloma.