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prof. dr. F.W. (Folkert) Asselbergs

prof. dr. F.W. (Folkert) Asselbergs

Full Professor
prof. dr. F.W. (Folkert) Asselbergs
  • Division of Heart & Lungs

Research Programs

Circulatory Health

Biography

Biography

Prof Dr. Folkert W. Asselbergs is Professor of Precision medicine at Institute of Health Informatics and the institute of Cardiovasculair Science, University College London, Director of the NIHR BRC UCL/UCLH Clinical and Research Informatics Unit, consultant cardiologist and Professor of Precision Medicine at University Medical Center Utrecht, University of Utrecht, the Netherlands, associate editor European Heart Journal, section digital health and innovation, Chair Center for Circulatory Health, UMC Utrecht, and chair data infrastructure Dutch Cardiovascular Alliance (www.dcvalliance.nl). 

 

Professor Asselbergs published more than 400 scientific papers in the field of cardiovascular disease and his work has been funded by the Netherlands Heart Foundation, Netherlands Heart Institute, British Heart Foundation, leDucq Foundation, EU FP7, European Society of Cardiology, BBMRI, National Institutes of Health, Innovative Medicines Initiative, European Research Area Network on Cardiovascular Diseases and ZonMw.

 

His research program in complex genetics focuses on the discovery of genes influencing susceptibility to cardiovascular disease; the application of these findings for the validation of drug targets; and the use of genetic tests for treatment targeting (stratified medicine). Lately, he widened his research focus to precision medicine using linked data sources such as wearable information and routine care data obtained from electronic health records including free text. His ambition is to build a network for performing clinical trials within routine health care linked to national registries. 

 

Prof Asselbergs is member of a large number of consortia and (co-) founded several consortia of which igenetrain (www.igenetrain.net), and GENIUS-CHD (www.genius-chd.org), and CAPACITY-COVID ( https://capacity-covid.eu)  are the most prominent and recent ones. He is scientific coordinator of European IMI Bigdate@heart consortium (www.bigdata-heart.eu). Bigdata@heart aims to deliver clinically relevant disease cardiovascular phenotypes, scalable insights from real-world evidence including data from registries, wearables and electronic health records, and insight driving drug development and personalized medicine through advanced big-data analytics. 

 

Side Activities

  • Prof of Precision medicine at the Institute of Cardiovascular Science and Institute of Director
  • Director Clinical Research Informatics Unit, University College London HospitalHealth Informatics, University College London
  • Medical Scientific Board Member "Deep".
  • Manager Research Center for Circulatory Health, UMC Utrecht

Fellowship and Awards

2014 - Dr. E. Dekker Scholarship of the Netherlands Heart Foundation (2014T001)

2012 - Fellow of the European Society of Cardiology

2010 - Clinical fellowship from the Netherlands Organisation for Health Research and Development(ZonMw grant 90700342)

2003  - Dr. E. Dekker Scholarship of the Netherlands Heart Foundation(NHS 2003T010)

Research Output (387)

Right Ventricular Functional Abnormalities in Arrhythmogenic Cardiomyopathy:Association With Life-Threatening Ventricular Arrhythmias

Kirkels Feddo P., Lie Øyvind H., Cramer Maarten J., Chivulescu Monica, Rootwelt-Norberg Christine, Asselbergs Folkert W., Teske Arco J., Haugaa Kristina H. mei 2021, In: JACC: Cardiovascular Imaging. 14 , p. 900-910 11 p.

Clopidogrel in noncarriers of CYP2C19 loss-of-function alleles versus ticagrelor in elderly patients with acute coronary syndrome:A pre-specified sub analysis from the POPular Genetics and POPular Age trials CYP2C19 alleles in elderly patients

Claassens Daniel M F, Gimbel Marieke E, Bergmeijer Thomas O, Vos Gerrit J A, Hermanides Renicus S, van der Harst Pim, Barbato Emanuele, Morisco Carmine, Tjon Joe Gin Richard M, de Vrey Evelyn A, Heestermans Ton A C M, Jukema J Wouter, von Birgelen Clemens, Waalewijn Reinier A, Hofma Sjoerd H, den Hartog Frank R, Voskuil Michiel, Van't Hof Arnoud W J, Asselbergs Folkert W, Mosterd A, Herrman Jean-Paul R, DeWilde Willem, Mahmoodi Bakhtawar K, Deneer Vera H M, Ten Berg Jurriën M 19 apr 2021, In: International Journal of Cardiology. 334 , p. 10-17 8 p.

Propensity score-based analysis of long-term outcome of patients on HeartWare and HeartMate 3 left ventricular assist device support

Numan Lieke, Ramjankhan Faiz Z., Oberski Daniel L., Oerlemans Martinus I.F.J., Aarts Emmeke, Gianoli Monica, Van Der Heijden Joris J., De Jonge Nicolaas, Van Der Kaaij Niels P., Meuwese Christiaan L., Mokhles Mostafa M., Oppelaar Anne Marie, De Waal Eric E.C., Asselbergs Folkert W., Van Laake Linda W. apr 2021, In: ESC heart failure. 8 , p. 1596-1603 8 p.

Genome-wide analysis identifies novel susceptibility loci for myocardial infarction

Hartiala Jaana A, Han Yi, Jia Qiong, Hilser James R, Huang Pin, Gukasyan Janet, Schwartzman William S, Cai Zhiheng, Biswas Subarna, Trégouët David-Alexandre, Smith Nicholas L, Seldin Marcus, Pan Calvin, Mehrabian Margarete, Lusis Aldons J, Bazeley Peter, Sun Yan V, Liu Chang, Quyyumi Arshed A, Scholz Markus, Thiery Joachim, Delgado Graciela E, Kleber Marcus E, März Winfried, Howe Laurence J, Asselbergs Folkert W, van Vugt Marion, Vlachojannis Georgios J, Patel Riyaz S, Lyytikäinen Leo-Pekka, Kähönen Mika, Lehtimäki Terho, Nieminen Tuomo V M, Kuukasjärvi Pekka, Laurikka Jari O, Chang Xuling, Heng Chew-Kiat, Jiang Rong, Kraus William E, Hauser Elizabeth R, Ferguson Jane F, Reilly Muredach P, Ito Kaoru, Koyama Satoshi, Kamatani Yoichiro, Komuro Issei, Stolze Lindsey K, Romanoski Casey E, Khan Mohammad Daud, Turner Adam W, 1 mrt 2021, In: European heart journal. 42 , p. 919-933 15 p.

P62-positive aggregates are homogenously distributed in the myocardium and associated with the type of mutation in genetic cardiomyopathy

van der Klooster Zoë Joy, Sepehrkhouy Shahrzad, Dooijes Dennis, Te Rijdt Wouter P, Schuiringa Frederique S A M, Lingeman Jolanthe, van Tintelen Johannes Peter, Harakalova Magdalena, Goldschmeding Roel, Suurmeijer Albert J H, Asselbergs Folkert W, Vink Aryan 18 feb 2021, In: Journal of Cellular and Molecular Medicine. 25 , p. 3160-3166 7 p.

Sex Differences in the Risk of Coronary Heart Disease Associated With Type 2 Diabetes:A Mendelian Randomization Analysis

Peters Tricia M, Holmes Michael V, Richards J Brent, Palmer Tom, Forgetta Vincenzo, Lindgren Cecilia M, Asselbergs Folkert W, Nelson Christopher P, Samani Nilesh J, McCarthy Mark I, Mahajan Anubha, Davey Smith George, Woodward Mark, O'Keeffe Linda M, Peters Sanne A E feb 2021, In: Diabetes Care. 44 , p. 556-562 7 p.

Risk Factors and Prevalence of Dilated Cardiomyopathy in Sub-Saharan Africa:Protocol for a Systematic Review

Fundikira Lulu Said, Chillo Pilly, van Laake Linda W, Mutagaywa Reuben Kato, Schmidt Amand Floriaan, Kamuhabwa Appolinary, Kwesigabo Gideon, Asselbergs Folkert W 21 jan 2021, In: JMIR Research Protocols. 10

The new European Heart Journal Digital Health and Innovations Team

Vardas Panos, Asselbergs Folkert, van Smeden Marteen 7 jan 2021, In: European heart journal. 42 , p. 1823-1824 2 p.

All research output

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