dr. M. Bartels

Assistant Professor - medical

  • Haematology patient care
  • Hematology/Van Creveldclinic

dr. M. Bartels

Research Programs


Marije Bartels, MD, PhD is a pediatric hematologist working at the Pediatric Hematology department of the Wilhelmina Children’s Hospital/UMC Utrecht. She has a special interest in inherited bone marrow failure syndromes, and rare anemias. Following her PhD thesis in 2014, she continued her research on epigenomic regulation of myeloid disorders and on the biology of inherited bone marrow failure syndromes with a special focus on Diamond-Blackfan anemia and Severe Congenital Neutropenia.

Marije is an active member of national and international committees concerning bone marrow failure disorders in children (including PNH), and red blood cell pathology.

Side Activities

    • European Diamond Blackfan Consortium (EuroDBA) 

    • Scientific Working Group on Granulocytes and Constitutional Marrow Failure Disordres (European Hematology Association) 

    • Scientific Working Group on Red Cells and Iron Metabolism (European Hematology Association) 

    • Severe Chronic Neutropenia International Registry/Consortium

    • National working committee PNH (paroxsymal nocturnal hemoglobinuria)

    • National working committee bone marrow failure (within  “sectie kinderhematologie”)

    • Medical committee “Villa Pardoes” 

Fellowship and Awards

  • 2013 Wilhelmina Children’s hospital Fund: Leading ladies research stimulation grant €125.000 euro

    2012 American Society of Hematology (ASH) Abstract Achievement Award


Research Output (23)

AML Subtype Is a Major Determinant of the Association between Prognostic Gene Expression Signatures and Their Clinical Significance

Wiggers Caroline R M, Baak Mirna L, Sonneveld Edwin, Nieuwenhuis Edward E S, Bartels Marije, Creyghton Menno P 10 sep 2019, In: Cell Reports. 28 , p. 2866-2877.e5

Recognizing a Non-classical Telomeropathy before Hematopoietic Stem Cell Transplantation in Pediatric Patients:A Case Series

Nederlof Iris, Lindemans Caroline A, Bierings Marc B, Mohseny Alexander B, Bresters Dorine, Bartels Marije aug 2019, In: HemaSphere. 3

The Complexity of Genotype-Phenotype Correlations in Hereditary Spherocytosis:A Cohort of 95 Patients: Genotype-Phenotype Correlation in Hereditary Spherocytosis

van Vuren Annelies, van der Zwaag Bert, Huisjes Rick, Lak Nathalie, Bierings Marc, Gerritsen Egbert, van Beers Eduard, Bartels Marije, van Wijk Richard aug 2019, In: HemaSphere. 3

Transcriptomic and Epigenomic Profiling of Histone Deacetylase Inhibitor Treatment Reveals Distinct Gene Regulation Profiles Leading to Impaired Neutrophil Development

Govers Anita M A P, Wiggers Caroline R M, van Boxtel Ruben, Mokry Michal, Nieuwenhuis Edward E S, Creyghton Menno P, Bartels Marije, Coffer Paul J aug 2019, In: HemaSphere. 3

Red Blood Cells:Chasing Interactions

Pretini Virginia, Koenen Mischa H, Kaestner Lars, Fens Marcel H A M, Schiffelers Raymond M, Bartels Marije, Van Wijk Richard 31 jul 2019, In: Frontiers in Physiology. 10

Characterization of the phenotype of human eosinophils and their progenitors in the bone marrow of healthy individuals

Hassani Marwan, van Staveren Selma, van Grinsven Erinke, Bartels Marije, Tesselaar Kiki, Leijte Guus, Kox Mathijs, Pickkers Peter, Vrisekoop Nienke, Koenderman Leo 17 mei 2019, In: Haematologica. 105 , p. e52-e56 5 p.

Epigenetic drug screen identifies the histone deacetylase inhibitor NSC3852 as a potential novel drug for the treatment of pediatric acute myeloid leukemia

Wiggers Caroline R M, Govers Anita M A P, Lelieveld Daphne, Egan David A, Zwaan C Michel, Sonneveld Edwin, Coffer Paul J, Bartels Marije 1 mei 2019, In: Pediatric Blood & Cancer. 66

Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients

Rab Minke A.E., van Oirschot Brigitte A., Bos Jennifer, Merkx Tesy H., van Wesel Annet C.W., Abdulmalik Osheiza, Safo Martin K., Versluijs Birgitta A., Houwing Maite E., Cnossen Marjon H., Riedl Jurgen, Schutgens Roger E.G., Pasterkamp Gerard, Bartels Marije, van Beers Eduard J., van Wijk Richard 19 feb 2019, In: American Journal of Hematology. 94 , p. 575-584 10 p.

How I manage children with Diamond-Blackfan anaemia

Bartels Marije, Bierings Marc 4 dec 2018, In: British Journal of Haematology. 184 , p. 123-133 11 p.

Inzichten in ernstige chronische neutropenie:Een handboek voor patiënten en hun families

Bartels M. 1 dec 2018, 60 p.

All Research Output (23)