H.D.M. Beekman

H.D.M. Beekman

Research Analyst
  • Department of Medical Physiology

Research Programs

Circulatory Health

Research Output (48)

Interplay between temporal and spatial dispersion of repolarization in the initiation and perpetuation of torsades de pointes in the chronic atrioventricular block dog

Smoczyńska Agnieszka, Aarnink Errol W, Dunnink Albert, Bossu Alexandre, van Weperen Valerie Y H, Meijborg Veronique M F, Beekman Henriëtte D M, Coronel R, Vos Marc A 1 sep 2021, In: American Journal of Physiology-Heart and Circulatory Physiology. 321 , p. H569-H576

Severe Bradycardia Increases the Incidence and Severity of Torsade de Pointes Arrhythmias by Augmenting Preexistent Spatial Dispersion of Repolarization in the CAVB Dog Model

van Weperen Valerie Y.H., Dunnink Albert, Bossu Alexandre, Beekman Jet D.M., Meijborg Veronique M.F., de Bakker Jacques M.T., Coronel Ruben, Varkevisser Rosanne, van der Heyden Marcel A.G., Vos Marc A. 26 apr 2021, In: Frontiers in Physiology. 12 , p. 1-10 10 p.

Evaluation of a Fully Automatic Measurement of Short-Term Variability of Repolarization on Intracardiac Electrograms in the Chronic Atrioventricular Block Dog

Smoczyńska Agnieszka, Sprenkeler David J., Aranda Alfonso, Beekman Jet D.M., Bossu Alexandre, Dunnink Albert, Wijers Sofieke C., Stegemann Berthold, Meine Mathias, Vos Marc A. 21 aug 2020, In: Frontiers in Physiology. 11 11 p.

High-rate pacing guided by short-term variability of repolarization prevents imminent ventricular arrhythmias automatically by an implantable cardioverter-defibrillator in the chronic atrioventricular block dog model

Smoczyńska Agnieszka, Loen Vera, Aranda Alfonso, Beekman Henriëtte D M, Meine Mathias, Vos Marc A 22 jul 2020, In: Heart Rhythm. 17 , p. 2078-2085 8 p.

LUF7244, an allosteric modulator/activator of K <sub>v</sub>11.1 channels, counteracts dofetilide-induced torsades de pointes arrhythmia in the chronic atrioventricular block dog model

Qile Muge, Beekman Henriette D M, Sprenkeler David J, Houtman Marien J C, van Ham W B, Stary-Weinzinger Anna, Beyl Stanislav, Hering Steffen, van den Berg Dirk-Jan, de Lange Elizabeth C M, Heitman Laura H, IJzerman Ad P, Vos Marc A, van der Heyden Marcel A G 24 jul 2019, In: British Journal of Pharmacology. 176 , p. 3871-3885 15 p.

The Increment of Short-term Variability of Repolarisation Determines the Severity of the Imminent Arrhythmic Outcome

Smoczynska Aga, Beekman HDM, Vos Marc A 8 jul 2019, In: Arrhythmia & electrophysiology review. 8 , p. 166-172 7 p.

Istaroxime, a positive inotropic agent devoid of proarrhythmic properties in sensitive chronic atrioventricular block dogs

Bossu Alexandre, Kostense Amée, Beekman Henriette D M, Houtman Marien J C, van der Heyden Marcel A G, Vos Marc A jul 2018, In: Pharmacological Research. 133 , p. 132-140 9 p.

Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia

Bossu Alexandre, Houtman Marien J C, Meijborg Veronique M F, Varkevisser Rosanne, Beekman Henriette D M, Dunnink Albert, de Bakker Jacques M T, Mollova Nevena, Rajamani Sridharan, Belardinelli Luiz, van der Heyden Marcel A G, Vos Marc A jun 2018, In: British Journal of Pharmacology. 175 , p. 2470-2482 13 p.

Beat-to-beat variations in activation-recovery interval derived from the right ventricular electrogram can monitor arrhythmic risk under anesthetic and awake conditions in the canine chronic atrioventricular block model

Wijers Sofieke C., Sprenkeler David J., Bossu Alexandre, Dunnink Albert, Beekman Jet D.M., Varkevisser Rosanne, Hernández Alfonso Aranda, Meine Mathias, Vos Marc A. 1 mrt 2018, In: Heart Rhythm. 15 , p. 442-448 7 p.

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