prof. dr. L.J. Bont
prof. dr. L.J. Bont
- Center for Translational Immunology (CTI) Research
- Infectious Diseases Research 2
Research Programs
Biography
Biography
Louis Bont is a Paediatrician Infectiologist at the Wilhelmina Children’s Hospital in the University Medical Center Utrecht, The Netherlands. He leads the Utrecht RSV Research Group. He is the coordinator of the Interest Group on Respiratory Infections of the European Society of Pediatric Infectious Diseases (ESPID) Research Committee. Dr. Bont is the founder and chairman of ReSViNET, an international RSV Research consortium. He has a strong interest in education of young talented researchers and founded the successful Training of Upcoming Leaders in Pediatric Science (TULIPS) career training program in the Netherlands. Dr. Bont served as advisor of the World Health Organization (WHO), the European Center of Disease Control (ECDC) and the Europarliament.
Louis Bont did his medical training at the Academic Medical Center in Amsterdam (1989-1996). He performed his PhD under the supervision of professor Jan Kimpen and professor Cobi Heijnen at the Wilhelmina Children’s Hospital (1997-2000). He was a post-doc at the Garofalo lab in Galveston, Texas (2000-2001). After returning to Utrecht, he followed the pediatric residency program followed by a pediatric infectious diseases and immunology fellowship. He have led the RSV Research Group since 2003 and became full professor in 2015.
The vision of his research is to combine clinical and basic research to decrease the global burden of RSV infection. The mission of his research group is to improve knowledge of RSV epidemiology, and to develop safe and effective therapeutic and preventive interventions.
In his work collaborate with patients is of highest importance. His work is supported by the RSV Patient Advisory Board (PAB) since 2012. The PAB has reviewed every grant application by the RSV Research Group. PAB members have been interviewed for newspapers and national television on RSV-related subjects.
Louis Bont actively participates as a teacher in the SUMMA program. In addition, he founded the TULIPS program in 2008 to train colleagues and young clinician-scientists.
Since April 1st 2021, Louis has been given a new position as medical scientific division manager of the Children's Division of the Wilhelmina Children's Hospital in Utrecht.
Side Activities
Sideactivities. Payment are always to UMC Utrecht
A. related to RSV infection
Advisory boards, consultancy and steering committees
- GlaxoSmithKline, Advisory Board (from 2020 onwards), (>€2200.-)
- Janssen, Global virtual advisory board, (from 2021 onwards), (>€2200.-)
- Julius Clinical, Advisor research, (from 2021 onwards) (>€2200.-)
- AstraZeneca, (2019 onward), (>€2200)
- MSD, Advisory Board, (from 2020 onwards) (>€2200.-)
- Pfizer (from 2021 onwards), (>€2200.-)
- Sanofi (from 2020 onwards), (>€2200.-)
- ESCMID, member executive committee member ESCMID Study Group for Respiratory viruses (from 2022 onwards), (no payment)
Meetings, speaker’s fees, chairing
- AstraZeneca, (2021 onwards, >€2200.-)
- AstraZeneca, Global Synagis filmed interview, (2021), (<€2200.-)
- GlaxoSmithKline, Virtual meeting, Consultancy, (2021), (<€2200.-)
- Janssen, speaker (2021), (<€2200.-)
- Merck Sharp & Dome, Speaker, (2021), (<€2200.-)
- Merck Sharp & Dome, RSV Passive Approaches and Niche SIE, (2021), (<€2200.-)
- Merck Sharp & Dome, RSV Airways Hyper-reactivity and Asthma, (2021), (<€2200.-)
- Merck Sharp & Dome, (Teleconference) Meetings SAC, (2020-2021), (<€2200.-)
- Sanofi, RSV Medical Education Meeting with experts, (2021), (<€2200.-)
- Sanofi, ReSiNET Symposium, (2021), (>€2200.-)
B. Sideactivities not related to RSV infection
- AstraZeneca, Consultant asthma, (2021), (<€2200.-)
- GSK, Data Safety Monitoring Board VZV vaccine, (2020) (>€2200.-)
- MediRisk, Expert Consultancy/Advisory, (2019), (<€2200.-)
- MeMed, Review KOL report, (2021) (>€2200.-)
- ESGREV executive committee (2022), (no payment)
Potential Conflicts of Interest
Dr. Bont has regular interaction with pharmaceutical and other industrial partners. He has not received personal fees or other personal benefits. UMCU has received major funding (>€100,000 per industrial partner) for investigator initiated studies from AbbVie, MedImmune, AstraZeneca, Sanofi, Janssen, Pfizer, MSD and MeMed Diagnostics. UMCU has received major funding for the RSV GOLD study from the Bill and Melinda Gates Foundation. UMCU has received major funding as part of the public private partnership IMI-funded RESCEU and PROMISE projects with partners GSK, Novavax, Janssen, AstraZeneca, Pfizer and Sanofi. UMCU has received major funding by Julius Clinical for participating in clinical studies sponsored by MedImmune and Pfizer. UMCU received minor funding (€1,000-25,000 per industrial partner) for consultation and invited lectures by AbbVie, MedImmune, Ablynx, Bavaria Nordic, MabXience, GSK, Novavax, Pfizer, Moderna, Astrazeneca, MSD, Sanofi, Janssen. Dr. Bont is the founding chairman of the ReSViNET Foundation.
Since April 1st 2021, Louis has been given a new position as medical scientific division manager of the Children's Division of the Wilhelmina Children's Hospital in Utrecht.
Fellowship and Awards
Full Professor (“Stimuleringshoogleraarschap”), expected in May 2015
International Congress of Pediatric Pulmunology (CIPP) Award for Contribution to Understanding Childhood Respiratory Disease and Global Medical Education (2013)
Dirkzwager-Assink Fonds Award by Catharijne Stichting for research on RSV bronchiolitis (2010)
Ter Meulen Fonds lecture: It is not all asthma that wheezes. 27e Congres Nederlandse Vereniging voor Kindergeneeskunde, Veldhoven (2005)
ESPID Fellowship Award 2001 Immunopathogenetic mechanisms of RSV infection in the mouse model (2001)
Royal Dutch Academy of Science (Ter Meulen Fonds Stipendium). Immunopathogenetic mechanisms of RSV infection in the mouse model (2000)
Research Output (293)
Sanders Sharon L, Agwan Sushil, Hassan Mohamed, Bont Louis J, Venekamp Roderick P 23 Oct 2023, In: The Cochrane database of systematic reviews. 2023
de Bruin Odette, Phijffer Emily, Ahmadizar Fariba, van der Maas Nicoline, Wildenbeest Joanne, Sturkenboom Miriam, Bont Louis, Bloemenkamp Kitty Oct 2023, In: BMJ global health. 8 14 p.
Löwensteyn Yvette N, Zheng Zhe, Rave Neele, Bannier Michiel A G E, Billard Marie-Noëlle, Casalegno Jean-Sebastien, Pitzer Virginia E, Wildenbeest Joanne G, Weinberger Daniel M, Bont Louis, 21 Jul 2023, In: The Journal of infectious diseases. 228 , p. 1394-1399 6 p.
Langedijk Annefleur C, Vrancken Bram, Lebbink Robert Jan, Evers Anouk, Pieciak Rachel C, Lemey Philippe, Bont Louis J, Gill Christopher J 20 Jul 2023, In: The Pediatric infectious disease journal. 42 , p. e421-e423 3 p.
van der Velden Fabian J.S., Lim Emma, Gills Lily, Broadey Jasmin, Hayes Louise, Roberts Eve, Courtney Jack, Ball Joanne, Herberg Jethro, Galassini Rachel, Emonts Marieke, Levin Michael, Cunnington Aubrey, Kaforou Myrsini, Wright Victoria, Bellos Evangelos, Broderick Claire, Channon-Wells Samuel, Cooray Samantha, De Tisham, D’Souza Giselle, Elorrieta Leire Estramiana, Estrada-Rivadeneyra Diego, Habgood-Coote Dominic, Hamilton Shea, Jackson Heather, Kavanagh James, Marjaneh Mahdi Moradi, Nichols Samuel, Nijman Ruud, Patel Harsita, Pennisi Ivana, Powell Oliver, Reid Ruth, Shah Priyen, Vito Ortensia, Whittaker Elizabeth, Wilson Clare, Womersley Rebecca, Abdulla Amina, Darnell Sarah, Nagelkerke Sietse, van der Flier Michiel, Tissing Wim J.E., Vastert Sebastiaan J., Vijlbrief Daniel C., Bont Louis J., Wolfs Tom F.W., Beudeker Coco R., Hulsmann Sanne C., 5 Jul 2023, In: BMC Medical Ethics. 24 , p. 1-11
Ho Antonia, Orton Richard, Tayler Rachel, Asamaphan Patawee, Herder Vanessa, Davis Chris, Tong Lily, Smollett Katherine, Manali Maria, Allan Jay, Rawlik Konrad, McDonald Sarah E., Vink Elen, Pollock Louisa, Gannon Louise, Evans Clair, McMenamin Jim, Roy Kirsty, Marsh Kimberly, Divala Titus, Holden Matthew T.G., Lockhart Michael, Yirrell David, Currie Sandra, O’Leary Maureen, Henderson David, Shepherd Samantha J., Jackson Celia, Gunson Rory, MacLean Alasdair, McInnes Neil, Bradley-Stewart Amanda, Battle Richard, Hollenbach Jill A., Henderson Paul, Odam Miranda, Chikowore Primrose, Oosthuyzen Wilna, van den Berg J. M.Merlijn, Nagelkerke Sietse, van der Flier Michiel, Tissing Wim J.E., Wösten-van Asperen Roelie M., Vastert Sebastiaan J., Vijlbrief Daniel C., Bont Louis J., Wolfs Tom F.W., Beudeker Coco R., Tempel Dennie, van Keulen Danielle, , 30 May 2023, In: Nature. 617 , p. 555-563 9 p.
Billard MN, Bont Louis J 20 May 2023, In: Lancet (London, England). 401 , p. 1632-1633 2 p.
Morfopoulou Sofia, Buddle Sarah, Torres Montaguth Oscar Enrique, Atkinson Laura, Guerra-Assunção José Afonso, Moradi Marjaneh Mahdi, Zennezini Chiozzi Riccardo, Storey Nathaniel, Campos Luis, Hutchinson J. Ciaran, Counsell John R., Pollara Gabriele, Roy Sunando, Venturini Cristina, Antinao Diaz Juan F., Siam Ala’a, Tappouni Luke J., Asgarian Zeinab, Ng Joanne, Hanlon Killian S., Lennon Alexander, McArdle Andrew, Czap Agata, Rosenheim Joshua, Andrade Catarina, Anderson Glenn, Lee Jack C.D., Williams Rachel, Williams Charlotte A., Tutill Helena, Nagelkerke Sietse, van der Flier Michiel, Tissing Wim J.E., Wösten-van Asperen Roelie M., Vastert Sebastiaan J., Vijlbrief Daniel C., Bont Louis J., Wolfs Tom F.W., Beudeker Coco R., Tempel Dennie, van Keulen Danielle, de Groot Ronald, van der Flier Michiel, van Aerde Koen, Heidema J., Miedema C. J., Jongerius Ilse, van den Berg J. M., Schonenberg D., Zandstra Judith, , , 18 May 2023, In: Nature. 617 , p. 564-573 10 p.
Carbonell-Estrany Xavier, Simões Eric Af, Bont Louis J., Paes Bosco A., 1 May 2023, In: The Lancet. Global health. 11 , p. e655-e657
Mao Zhuxin, Li Xiao, Dacosta-Urbieta Ana, Billard Marie Noëlle, Wildenbeest Joanne, Korsten Koos, Martinón-Torres Federico, Heikkinen Terho, Cunningham Steve, Snape Matthew D., Robinson Hannah, Pollard Andrew J., Postma Maarten, Dervaux Benoit, Hens Niel, Bont Louis, Bilcke Joke, Beutels Philippe, 18 Mar 2023, In: Vaccine. 41 , p. 2707-2715 9 p.