Wij zijn onze website aan het vernieuwen.

Ontdekt u nog een pagina die niet klopt of hebt u een goede suggestie, laat het ons dan weten via webmedia@umcutrecht.nl.

Deze website maakt gebruik van cookies

Deze website toont video’s van o.a. YouTube. Dergelijke partijen plaatsen cookies (third party cookies). Als u deze cookies niet wilt kunt u dat hier aangeven. Lees meer over het cookiebeleid.

prof. dr. M.J.M. (Marc ) Bonten Full Professor

  • Department of Epidemiology
  • Department of Medical Microbiology
  • Julius Center Research Program Infectious Diseases

M.J.M. Bonten

Contact

Research Programs

Biography

Marc Bonten earned his MD (1991) and PhD (“the role of colonization of the upper intestinal tract in the pathogenesis of ventilator-associated pneumonia, 1994) at the Maastricht University Medical School, the Netherlands. He registered as internist in 2000, as infectious disease specialist in 2002 and as clinical microbiologist in 2008, all at the University Medical Center Utrecht, the Netherlands. Since August 2008 he is head of the Department of Medical Microbiology and leading the research group of infectious Disease Epidemiology of the Julius Center of Health Sciences and Primary Care, both at the UMC Utrecht, where he is professor of molecular epidemiology of infectious diseases since 2002. He has been a principal investigator in many large scale epidemiologic studies and investigator-initiated randomized trials of prevention and treatment of infectious diseases. His experience covers the full range of epidemiologic study designs including clinical trials, cohorts, case-control studies and mathematical modelling to study antibiotic resistance and infection prevention. Specific research interests include the epidemiology of antibiotic-resistant bacteria such as VRE, MRSA and MDR Enterobacteriaceae, selective decontamination in intensive care unit patients, prevention of ventilator-associated pneumonia, treatment of community-acquired pneumonia, and prevention and treatment of community-acquired pneumonia.

Since 2016 he is the Scientific Director of the research theme "Tackling Antimicrobial Resistance" of the Netherlands Centre for One Health (NCOH; www.ncoh.nl).

Since 2017 he is the chairman of the focus area Infection & Immunity at the UMC Utrecht, and board member of the Netherlands Antibiotic Development Platform (NADP; www.nadp.nl).

Side Activities

  • He acts as paid consultant for Janssen Vaccines (payments to UMC Utrecht) and Merck Sharp & Dohme B.V. (payments to UMC Utrecht).

    He has received speakers fee from Takeda (Nov 2019).

    He is a member of the Expertpanel of the Stichting Dierenautoriteit Nederland.

    He is a member of the cluster Infectieziektenbestrijding from ZorgOnderzoek Nederland. 

    He is a member of the Scientific Advisory Board of GARDP (Global Antibiotic Research & Development Platform).

     

Fellowship and Awards

  • He has been (co-)applicant of a large number of national and international research grants. He is a VICI laureate (2006) from the Dutch Science Association, Principal Investigator of the CAPiTA study, coordinator of the EU-funded project R-GNOSIS, scientific coordinator of the IMI-funded consortiums COMBACTE-NET, COMBACTE-CARE and COMBACTE-MAGNET, and Work Package leader of the REMAP-CAP ICU study in PREPARE.


    In 2015 he received the ESCMID 2015 Award for Excellence in Clinical Microbiology and Infectious Diseases.

    In 2017 he received a honorary fellowship of the Royal College of Physicians of Ireland, and was awarded the ESCMID fellowship.

Research Output (427)

Correction to:Predicting the clinical trajectory in critically ill patients with sepsis: a cohort study

Klein Klouwenberg Peter M C, Spitoni Cristian, van der Poll Tom, Bonten Marc J, Cremer Olaf L, 6 feb 2020, In: Critical care (London, England). 24

Extended-spectrum beta-lactamase (ESBL)-producing and non-ESBL-producing Escherichia coli isolates causing bacteremia in the Netherlands (2014 - 2016) differ in clonal distribution, antimicrobial resistance gene and virulence gene content

van Hout Denise, Verschuuren Tess D, Bruijning-Verhagen Patricia C J, Bosch Thijs, Schürch Anita C, Willems Rob J L, Bonten Marc J M, Kluytmans Jan A J W 1 jan 2020, In: PLoS ONE. 15 14 p.

Predicting the clinical trajectory in critically ill patients with sepsis:a cohort study

Klein Klouwenberg Peter M C, Spitoni Cristian, van der Poll Tom, Bonten Marc J, Cremer Olaf L, 12 dec 2019, In: Critical care (London, England). 23

In vivo acquisition of fosfomycin resistance in Escherichia coli by fosA transmission from commensal flora

Ten Doesschate Thijs, Abbott Iain J., Willems Rob J.L., Top Janetta, Rogers Malbert R.C., Bonten Marc M., Paganelli Fernanda L. 1 dec 2019, In: The Journal of antimicrobial chemotherapy. 74 , p. 3630-3632 3 p.

Elaboration of Consensus Clinical Endpoints to Evaluate Antimicrobial Treatment Efficacy in Future Hospital-acquired/Ventilator-associated Bacterial Pneumonia Clinical Trials

Weiss Emmanuel, Zahar Jean-Ralph, Alder Jeff, Asehnoune Karim, Bassetti Matteo, Bonten Marc J. M., Chastre Jean, De Waele Jan, Dimopoulos George, Eggimann Philippe, Engelhardt Marc, Ewig Santiago, Kollef Marin, Lipman Jeffrey, Luna Carlos, Martin-Loeches Ignacio, Pagani Leonardo, Palmer Lucy B., Papazian Laurent, Poulakou Garyphallia, Prokocimer Philippe, Rello Jordi, Rex John H., Shorr Andrew F., Talbot George H., Thamlikitkul Visanu, Torres Antoni, Wunderink Richard G., Timsit Jean-Francois 1 dec 2019, In: Clinical Infectious Diseases. 69 , p. 1912-1918 7 p.

A pilot study of a novel molecular host response assay to diagnose infection in patients after high-risk gastro-intestinal surgery

Verboom Diana M, Koster-Brouwer Maria E, Ruurda Jelle P, van Hillegersberg Richard, van Berge Henegouwen Mark I, Gisbertz Suzanne S, Scicluna Brendon P, Bonten Marc J M, Cremer Olaf L dec 2019, In: Journal of Critical Care. 54 , p. 83-87 5 p.

The added value of the selective SuperPolymyxin™ medium in detecting rectal carriage of Gram-negative bacteria with acquired colistin resistance in intensive care unit patients receiving selective digestive decontamination

van Hout Denise, Janssen Axel B, Rentenaar Rob J, Vlooswijk Judith P M, Boel C H Edwin, Bonten Marc J M 6 nov 2019, In: European Journal of Clinical Microbiology & Infectious Diseases. 39 , p. 265-271 7 p.

Sequence-Based Epidemiology of an OXA-48 Plasmid during Hospital Outbreak

Hidalgo Laura, de Been Mark, Rogers Malbert R C, Schürch Anita C, Scharringa Jelle, van der Zee Anneke, Bonten Marc J M, Fluit Ad C 7 okt 2019, In: Antimicrobial Agents and Chemotherapy. 63

Sequence-Based Epidemiology of an OXA-48 Plasmid during Hospital Outbreak

Hidalgo Laura, de Been Mark, Rogers Malbert R C, Schürch Anita C, Scharringa Jelle, van der Zee Anneke, Bonten Marc J M, Fluit Ad C 7 okt 2019, In: Antimicrobial Agents and Chemotherapy. 63

Prevalence, risk factors and genetic characterisation of extended-spectrum beta-lactamase and carbapenemase-producing Enterobacteriaceae (ESBL-E and CPE): a community-based cross-sectional study, the Netherlands, 2014 to 2016

van den Bunt Gerrita, van Pelt Wilfrid, Hidalgo Laura, Scharringa Jelle, de Greeff Sabine C., Schurch Anita C., Mughini-Gras Lapo, Bonten Marc J. M., Fluit Ad C. 1 okt 2019, In: Eurosurveillance. 24 , p. 29-39 11 p.

All Research Output (427)
To top