dr. A.M.E. (Annelies) Bos

dr. A.M.E. (Annelies) Bos

Associate Professor - medical
dr. A.M.E. (Annelies) Bos
  • Reproductive Medicine & Gynecology - Medical



Doctorate                        5th of March, 2003

                                             Thesis: Optimizing conventional chemotherapy approaches.                                                                              Studies on feasibility and pharmacokinetics.

                                             Promotores: Prof. dr. E.G.E. de Vries and Prof. dr. A.G.J. van der                                                         Zee, co-promotor: Dr. P.H.B. Willemse

                                             Department Medical Oncology/Gynaecology-Oncology UMC Groningen


Current position           July 2010-now: Consultant, Fertility and Gynecology department, University Medical Center Utrecht


Prior positions              -1988-1995: Medicine Study, Rijksuniversiteit Groningen


                                             -Aug 1995-Okt 1995: Resident Internal Medicine

                                             De Weezenlanden Hospital, Zwolle


                                             -Okt 1995-May 1997: Resident Gynecology/Obstetrics

                                             De Weezenlanden Hospital, Zwolle


                                             May 1997- Febr 1998: Resident Gynecology/Obstetrics

                                             Martini Hospital, Groningen


                                             Febr 1998- July 2000: Resident and researcher Medical Oncology & Gynaecology Oncology, University Medical Center Groningen


                                             July 2000-July 2006: Traineeship  Gynecology and                                                                                   Obstetrics:  Isala Klinieken Zwolle, University Medical Center                                                                            Groningen and Medical Center Leeuwarden.


                                             2006-2010: Consultant, Fertility and Gynecology department, University Medical Center Groningen


                                             2008-July 2010: Consultant and Subspecialisation                                                                                    Fertility and Endocrinology, University Medical Center                                                                          Groningen


Side Activities

Current Professional memberships

Member of the Dutch Network Gynaecology and Obstetrics (NVOG) >2000


Member European Society Human Reproduction and Endocrinology (ESHRE) >2008


Member Dutch Working party Gynaecological Endoscopy (WGE) (>2012)


Member of the oncologic Mamma Team in the UMC Utrecht (>2011)


Member and secretary (since May 2015) of the Dutch Special Interest Group Fertility preservation (NVOG)


Member of the Special Interest Group Gamete donation (NVOG) >2016


Secretary and vice-president of the Medical Ethical Board of the Department Fertility UMC Utrecht, since April 2015


Member of the Dutch Society of Gender and Health (NVG&G) >2018 (before member of the Alliance Gender and Health)


Chair of the working group Fertility patients in children with cancer in the Prinses Maxima Center.  (>June 2018)



Guideline development committees:


- Member of the Dutch Alliance of Gender and Health care (>2012), 2014-2016 making the ‘Kennisagenda Gender and Health’ by estimating knowledge gaps and aims for future research in the field of genderspecific medicine.


-2015-2016 Member of the working group of modern families (NVOG/cie Herijking Ouderschap)


- member of Dutch guideline group: Fertility preservation for women with cancer (2015-2016),


-Initiator and member of the Dutch working group SKION agreement Fertility Preservation for girls and adolescents 0-18 yrs (2016) (gynecologist and pediatric oncologists)


-Modelreglement Embryowet (NVOG and KLEM) Advisory board August 2018


-Member of the working group for development of fertility preservation guidelines in female cancer patients (0-18 years) as part of the IGHG project/PancareLife European project (>2016-2018).



Fellowship and Awards

Child Health Boost grant, sept 2017. 15K euro for the start-up of the EXOTiC project (Exploring the feasibility of EXcellent fertility counseling care for girls with cancer and the safety of Ovarian Tissue Cryopreservation on a national level).

Research team: Annelies Bos, Marry van den Heuvel-Eibrink, Marc Wijnen, Birgitta Versluijs, Simone Broer en Frank Broekmans

The proposed EXOTiC project will be the start of an integral part of the joint clinical and research program on fertility preservation care for children up to 19 years of age in the Princess Máxima Center for Pediatric Oncology and the Department of Reproductive Medicine, UMC Utrecht.


Research Output (21)

Development and testing of a tailored online fertility preservation decision aid for female cancer patients

van den Berg Michelle, van der Meij Elleke, Bos Annelies M E, Boshuizen Marieke C S, Determann Domino, van Eekeren Ramon R J P, Lok Christianne A R, Schaake Eva E, Witteveen Petronella O, Wondergem Marielle J, Braat Didi D M, Beerendonk Catharina C M, Hermens Rosella P M G mrt 2021, In: Cancer Medicine. 10 , p. 1576-1588 13 p.

Reproductive Complications in Childhood Cancer Survivors

van Santen Hanneke M, van de Wetering Marianne D, Bos Annelies M E, Vd Heuvel-Eibrink Marry M, van der Pal Helena J, Wallace William Hamish dec 2020, In: The pediatric clinics of North America. 67 , p. 1187-1202 16 p.

Onco-Fertility Care for Newly Diagnosed Girls With Cancer in a National Pediatric Oncology Setting, The First Experiences From the Princess Maxima Center, The Pearl Study

Van der Perk M. E. M., Van der Kooi A. -L., Van de Wetering M. D., Ijgosse I. M., Van Dulmen-Den Broeder E., Broer S. L., Veening M. A., Klijn A. J., Versluys A. B., Arends B., Ophuis R. J. A. Oude, Van Santen H. M., Van der Steeg A. F. W., Van den Heuvel-Eibrink M. M., Bos A. M. E. dec 2020, In: Pediatric Blood & Cancer. 67 , p. S30-S31

The Effect of Radioactive Iodine Therapy on Ovarian Function and Fertility in Female Thyroid Cancer Patients:A Systematic Review and Meta-Analysis

Piek Marceline W, Postma Emily L, van Leeuwaarde Rachel, de Boer Jan Paul, Bos Annelies M E, Lok Christianne, Stokkel Marcel, Filipe Mando D, van der Ploeg Iris M C 2 nov 2020, In: Thyroid. 31 , p. 658-668 11 p.

What constitutes a reasonable compensation for non-commercial oocyte donors:an analogy with living organ donation and medical research participation

Kool Emy, van der Graaf Rieke, Bos Annelies, Fauser Bartholomeus, Bredenoord Annelien 1 nov 2019, In: Journal of Medical Ethics. 45 , p. 736-741 6 p.

Stakeholders views on the ethical aspects of oocyte banking for third-party assisted reproduction:a qualitative interview study with donors, recipients and professionals

Kool E M, van der Graaf R, Bos A M E, Pieters J J P M, Custers I M, Fauser B C J M, Bredenoord A L 30 mrt 2019, In: Human Reproduction. 34 , p. 842-850 9 p.

Ethics of oocyte banking for third-party assisted reproduction:a systematic review

Kool E M, Bos A M E, van der Graaf R, Fauser B C J M, Bredenoord A L 2018, In: Human Reproduction Update. 24 , p. 615-635 21 p.

Stimulation of the ovaries in women with breast cancer undergoing fertility preservation:Alternative versus standard stimulation protocols; the study protocol of the STIM-trial

Dahhan T., Balkenende E.M., Beerendonk C. C.M., Fleischer K., Stoop D., Bos A. M.E., Lambalk Cornelis B., Schats R, van Golde Ron J T, Schipper I., Louwé L. A., Cantineau A. E.P., Smeenk Jesper M J, Bruin Jacob P, Reddy D N, Kopeika Y., van der Veen F, Wely M., Linn S. C., Goddijn M. 1 okt 2017, In: Contemporary Clinical Trials. 61 , p. 96-100 5 p.

Autonomy and self-esteem of women who donate to an oocyte cryopreservation bank in the Netherlands

Bakker Marjolein R, Maas Joyce, Bekker Marrie H, Bredenoord Annelien L, Fauser Bart C, Bos Annelies M aug 2017, In: Reproductive Biomedicine Online. 35 , p. 225-231

Vruchtbaarheid na kanker verdient meer aandacht

Beerendonk Ina, Bos AME, Witteveen E., Veening Margreet A. 12 jan 2017, In: Medisch Contact. 2 , p. 24-26

All research output

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