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dr. L.A.A. (Lodewijk) Brosens

dr. L.A.A. (Lodewijk) Brosens

Associate Professor - medical
dr. L.A.A. (Lodewijk) Brosens
  • Department of Pathology

Research Programs

Strategic Program Cancer

Biography

Biography

2015-present: Associate professor of pathology, gastrointestinal and endocrine pathology, UMC Utrecht.

2014-2015: Post-doctoral research fellow department of pathology Johns Hopkins Hospital, Baltimore

2013: Pathologist, gastrointestinal pathology, Academic Medical Center Amsterdam

2008-2013: Pathology residency

2008: PhD, Gastrointestinal polyposis syndromes, clinical and molecular aspects of Familial Adenomatous Polyposis en Juvenile Polyposis, Utrecht University

2006: M.D. University of Amsterdam

2004: MSc. Biomedical Science, Vrije Universiteit, Amsterdam

2003-2004: Research fellow Departments of Pathology and Gastroenterology, Johns Hopkins Hospital, Baltimore

Side Activities

Member of the scientific committee Dutch Pancreatic Cancer Group (DPCG)

Member of scientific council pancreas parel (nationwide biobank)

Member of scientific committee LWH Foundation

Member of Dutch working group on Barrett's esophagus

WHO Classification of Tumours 5Th Edition - Tumours of the Digestive System, co-author

WHO Classification of Tumours 5Th Edition - Endocrine and Neuroendocrine tumours Tumours, co-author

Associate Editor BMC Cancer

Pathologist RadboudUMC (0,2 fte) gastrointestinal and pancreatic pathology

Visiting professor of pathology, University of Verona, Italy

Associate Editor Cancer Biology & Therapy

 

Fellowship and Awards

2018: University of Verona Internationalization Program Stipend

2014: MLDS Career Development Grant

2013: UICC Yamagiwa-Yoshida Memorial international study grant

2013: Nijbakker-Morra Stichting Stipend

Research Output (205)

Perioperative or adjuvant mFOLFIRINOX for resectable pancreatic cancer (PREOPANC-3):study protocol for a multicenter randomized controlled trial

van Dam J L, Verkolf E M M, Dekker E N, Bonsing B A, Bratlie S O, Brosens L A A, Busch O R, van Driel L M J W, van Eijck C H J, Feshtali S, Ghorbani P, de Groot D J A, de Groot J W B, Haberkorn B C M, de Hingh I H, van der Holt B, Karsten T M, van der Kolk M B, Labori K J, Liem M S L, Loosveld O J L, Molenaar I Q, Polée M B, van Santvoort H C, de Vos-Geelen J, Wumkes M L, van Tienhoven G, Homs M Y V, Besselink M G, Wilmink J W, Groot Koerkamp B, Dec 2023, In: BMC Cancer. 23 , p. 728 8 p.

Somatic loss of ATM is a late event in pancreatic tumorigenesis

Paranal Raymond M, Jiang Zhengdong, Hutchings Danielle, Kryklyva Valentyna, Gauthier Christian, Fujikura Kohei, Nanda Neha, Huang Bo, Skaro Michael, Wolfgang Christopher L, He Jin, Klimstra David S, Brand Randall E, Singhi Aatur D, DeMarzo Angelo, Zheng Lei, Goggins Michael, Brosens Lodewijk Aa, Hruban Ralph H, Klein Alison P, Lotan Tamara, Wood Laura D, Roberts Nicholas J 22 Jun 2023, In: Journal of Pathology. 260 , p. 455-464 10 p.

Impact of network treatment in patients with resected pancreatic cancer on use and timing of chemotherapy and survival

Hopstaken Jana S, Vissers Pauline A J, Quispel Rutger, de Vos-Geelen Judith, Brosens Lodewijk A A, de Hingh Ignace H J T, van der Geest Lydia G, Besselink Marc G, van Laarhoven Kees J H M, Stommel Martijn W J 1 Jun 2023, In: BJS open. 7

Adequacy of endoscopic recognition and surveillance of gastric intestinal metaplasia and atrophic gastritis:A multicentre retrospective study in low incidence countries

Honing Judith, Keith Tan W, Dieninyte Egle, O'Donovan Maria, Brosens Lodewijk, Weusten Bas, di Pietro Massimiliano Jun 2023, In: PLoS ONE. 18

The apron of the greater omentum of gastric cancer patients contains various lymphoid structures including lymph nodes

Schurink B., Cleypool C. G.J., Brosens L. A.A., Ruurda J. P., Mackaaij Claire, Roeling T. A.P., van Hillegersberg R., Bleys R. L.A.W. Jun 2023, In: Translational Research in Anatomy. 31

Nationwide Impact of Centralization, Neoadjuvant Therapy, Minimally Invasive Surgery, and Standardized Pathology Reporting on R0 Resection and Overall Survival in Pancreatoduodenectomy for Pancreatic Cancer

Augustinus Simone, Schafrat Pascale J M, Janssen Boris V, Bonsing Bert A, Brosens Lodewijk A A, Busch Olivier R, Crobach Stijn, Doukas Michail, van Eijck Casper H, van der Geest Lydia G M, Groot Koerkamp Bas, de Hingh Ignace H J T, Raicu G Mihaela, van Santvoort Hjalmar C, van Velthuysen Marie-Louise, Verheij Joanne, Besselink Marc G, Farina Sarasqueta Arantza, 20 May 2023, In: Annals of Surgical Oncology. 30 , p. 5051-5060 10 p.

ASO Visual Abstract:Nationwide Impact of Centralization, Neoadjuvant Therapy, Minimally Invasive Surgery, and Standardized Pathology Reporting on R0 Resection and Overall Survival in Pancreatoduodenectomy for Pancreatic Cancer

Augustinus Simone, Schafrat Pascale J M, Janssen Boris V, Bonsing Bert A, Brosens Lodewijk A A, Busch Olivier R, Crobach Stijn, Doukas Michail, van Eijck Casper H, van der Geest Lydia G M, Groot Koerkamp Bas, de Hingh Ignace H J T, Raicu G Mihaela, van Santvoort Hjalmar C, van Velthuysen Marie-Louise, Verheij Joanne, Besselink Marc G, Farina Sarasqueta Arantza, 19 May 2023, In: Annals of Surgical Oncology. 30 , p. 5061-5062 2 p.

Diagnostic Utility of Menin Immunohistochemistry in Patients With Multiple Endocrine Neoplasia Type 1 Syndrome

Verschuur Anna Vera D, Kok Aranxa S M, Morsink Folkert H M, de Leng Wendy W J, van den Broek Medard F M, Koudijs Marco J, Offerhaus Johan A, Valk Gerlof D, Vriens Menno R, van Nesselrooij Bernadette P M, Hackeng Wenzel M, Brosens Lodewijk A A 18 May 2023, In: American Journal of Surgical Pathology. 47 , p. 785-791 7 p.

ASO Visual Abstract:Safety and Feasibility of Robot-Assisted Minimally Invasive Esophagectomy (RAMIE) with Three-Field Lymphadenectomy and Neoadjuvant Chemoradiotherapy in Patients with Resectable Esophageal Cancer and Cervical Lymph Node Metastasis

van der Horst S., Weijs T. J., Braunius W. W., Mook S., Mohammed N. Haj, Brosens L., van Rossum P. S.N., Weusten B. L.A.M., Ruurda J. P., van Hillegersberg R. 1 May 2023, In: Annals of surgical oncology. 30 , p. 2755-2756 2 p.

Safety and Feasibility of Robot-Assisted Minimally Invasive Esophagectomy (RAMIE) with Three-Field Lymphadenectomy and Neoadjuvant Chemoradiotherapy in Patients with Resectable Esophageal Cancer and Cervical Lymph Node Metastasis

van der Horst S., Weijs T. J., Braunius W. W., Mook S., Mohammed N. Haj, Brosens L., van Rossum P. S.N., Weusten B. L.A.M., Ruurda J. P., van Hillegersberg R. May 2023, In: Annals of surgical oncology. 30 , p. 2743-2752 10 p.

All research output

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