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T.R. (Thijn) Brummelkamp

T.R. (Thijn) Brummelkamp

Full Professor
  • Molecular Cancer Research

Research Programs

Cancer

Side Activities

  • UMCU - Hoogleraar
  • Oprichter Biotech Scenic biotech B.V. - aandeelhouder, sceientific advisor
  • Oprichter Haplogen GmbH - aandeelhouder, member scientific advisory board
  • Groepsleider - Nederlands Kanker Instituut
  • Member Oncode Institute

Research Output (7)

A Genome-Wide Haploid Genetic Screen Identifies Heparan Sulfate-Associated Genes and the Macropinocytosis Modulator TMED10 as Factors Supporting Vaccinia Virus Infection

Luteijn Rutger D, van Diemen Ferdy, Blomen Vincent A, Boer Ingrid G J, Manikam Sadasivam Saravanan, van Kuppevelt Toin H, Drexler Ingo, Brummelkamp Thijn R, Lebbink Robert Jan, Wiertz Emmanuel J 1 Jul 2019, In: Journal of Virology. 93

Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy

Logtenberg Meike E W, Jansen J H Marco, Raaben Matthijs, Toebes Mireille, Franke Katka, Brandsma Arianne M, Matlung Hanke L, Fauster Astrid, Gomez-Eerland Raquel, Bakker Noor A M, van der Schot Simone, Marijt Koen A, Verdoes Martijn, Haanen John B A G, van den Berg Joost H, Neefjes Jacques, van den Berg Timo K, Brummelkamp Thijn R, Leusen Jeanette H W, Scheeren Ferenc A, Schumacher Ton N Apr 2019, In: Nature Medicine. 25 , p. 612-619 8 p.

Nedd4-binding protein 1 and TNFAIP3-interacting protein 1 control MHC-1 display in neuroblastoma

Spel Lotte, Nieuwenhuis Joppe, Haarsma Rianne, Stickel Elmer, Bleijerveld Onno B, Altelaar Maarten, Boelens Jaap Jan, Brummelkamp Thijn R, Nierkens Stefan, Boes Marianne Dec 2018, In: Cancer Research. 78 , p. 6621-6631 11 p.

Vasohibins encode tubulin detyrosinating activity

Nieuwenhuis Joppe, Adamopoulos Athanassios, Bleijerveld Onno B., Mazouzi Abdelghani, Stickel Elmer, Celie Patrick, Altelaar A. F Maarten, Knipscheer Puck, Perrakis Anastassis, Blomen Vincent A., Brummelkamp Thijn R. 16 Nov 2017, In: Science. 358 , p. 1453-1456 4 p.

The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension

Haarhuis Judith H.I., van der Weide Robin H., Blomen Vincent A., Yáñez-Cuna J. Omar, Amendola Mario, van Ruiten Marjon S., Krijger Peter H. L., Teunissen Hans, Medema René H., van Steensel Bas, Brummelkamp Thijn R., de Wit Elzo, Rowland Benjamin D. 4 May 2017, In: Cell. 169 , p. 693-707.e14

Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension

Lens S. M A, Wolthuis R. M F, Klompmaker Rob, Kauw Jos, Agami Reuven, Brummelkamp Thijn, Kops Geert, Medema René H. 16 Jun 2003, In: EMBO Journal. 22 , p. 2934-2947 14 p.

Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector

van de Wetering M.L., Oving I.M., Muncan M., Pon Fong MT, Brantjes H.M., van Leenen D., Holstege F.C.P., Brummelkamp T., Agami R., Clevers H.C. 2003, In: EMBO Reports. 4 , p. 609-615 7 p.

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