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prof. dr. W. (Wiepke) Cahn Full Professor

  • Psychiatry

W. Cahn

Contact

Research Programs

Biography

Prof. Wiepke Cahn has been a research psychiatrist at the University Medical Center Utrecht since 1996. In 2003 she obtained her PhD titled ‘brain morphology during the early course of schizophrenia’. She has set up various (multicenter) research projects, including GROUP. She has been chief psychiatrist for the schizophrenia program at the UMCUtrecht and project manager for the Utrecht Youth Cohort. Currently she is heading the ‘body & life’ clinic at the department of psychiatry. In 2016 she was appointed professor of psychiatry. Her research interest is the physical (ill-)health in psychiatric disorders.

Wiepke Cahn is vice-president of the Dutch Psychiatric Association. She has authored more than 200 papers and book chapters and has been chief editor of ‘handboek schizofrenie’. Her non-research-based activities consist of treating patients and their families with psychotic and bipolar disorders.

Research Line

Physical health in psychiatric disorders

Most recent key publications

  1. Liemburg EJ, Bruins J, van Beveren N, Islam MA, Alizadeh BZ; GROUP investigators. Cannabis and a lower BMI in psychosis: What is the role of AKT1? Schizophr Res. 2016 Oct;176(2-3):95-9.
  2. de Nijs J, Pet MA; GROUP Investigators.. Metabolic syndrome in schizophrenia patients associated with poor premorbid school performance in early adolescence. Acta Psychiatr Scand. 2016 Apr;133(4):289-97.
  3. Scheewe TW, Backx FJ, Takken T, Jörg F, van Strater AC, Kroes AG, Kahn RS, Cahn W. Exercise therapy improves mental and physical health in schizophrenia: a randomised controlled trial. Acta Psychiatr Scand. 2013 Jun;127(6):464-73.
  4. Welie H, Derks EM, Verweij KH, de Valk HW, Kahn RS, Cahn W. The prevalence of diabetes mellitus is increased in relatives of patients with a non-affective psychotic disorder. Schizophr Res. 2013 Feb;143(2-3):354-7.
  5. Cahn W, Ramlal D, Bruggeman R, de Haan L, Scheepers FE, van Soest MM, Assies J, Slooff CJ. [Prevention and treatment of somatic complications arising from the use of antipsychotics]. Tijdschr Psychiatr. 2008;50(9):579-91.

 

Side Activities

  • GGz Breburg Supervisory Board

    Full Professor, Altrecht Science

Fellowship and Awards

    • Genetic Risk and Outcome of Psychosis (GROUP project) – i.s.m. AMC, UMCG en Universiteit van Maastricht
    • Topfit project – i.s.m. met sportgeneeskunde
    • GRUMPY or Depressed – i.s.m. de sociale faculteit UU
    • Adding in- and outpatient parmacotherapeutic treatment information – i.s.m. de faculteit farmaceutische wetenschappen
    • International panel study on the appropriate pharmacological management of early schizophrenia – RAND/UCLA study

Research Output (189)

Prevalence of metabolic syndrome and its associated risk factors in an African–Caribbean population with severe mental illness

de Caluwé Laura, van Buitenen Nora, Gelan Petra J., Crunelle Cleo L., Thomas Roeland, Casseres Sharon, Matthys Frieda, van Harten Peter, Cahn Wiepke 1 nov 2019, In: Psychiatry Research. 281

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal Claudia L., Adams Hieab H.H., Hibar Derrek P., White Charles C., Knol Maria J., Stein Jason L., Scholz Markus, Sargurupremraj Muralidharan, Jahanshad Neda, Roshchupkin Gennady V., Smith Albert V., Bis Joshua C., Jian Xueqiu, Luciano Michelle, Hofer Edith, Teumer Alexander, van der Lee Sven J., Yang Jingyun, Yanek Lisa R., Lee Tom V., Li Shuo, Hu Yanhui, Koh Jia Yu, Eicher John D., Desrivières Sylvane, Arias-Vasquez Alejandro, Chauhan Ganesh, Athanasiu Lavinia, Rentería Miguel E., Kim Sungeun, Hoehn David, Armstrong Nicola J., Chen Qiang, Holmes Avram J., den Braber Anouk, Kloszewska Iwona, Andersson Micael, Abramovic Lucija, Bohlken Marc M., Klein Marieke, Boks Marco P., van Eijk Kristel R., Cahn Wiepke, Hulshoff Pol Hilleke E., Ikram M. Kamran, Brouwer Rachel M., Kahn René S., Ophoff Roel A., van Haren Neeltje E.M., Schmidt Reinhold, 1 nov 2019, In: Nature Genetics. 51 , p. 1624-1636 13 p.

Shared vulnerability for connectome alterations across psychiatric and neurological brain disorders

de Lange Siemon C., Scholtens Lianne H., van den Berg Leonard H., Boks Marco P., Bozzali Marco, Cahn Wiepke, Dannlowski Udo, Durston Sarah, Geuze Elbert, van Haren Neeltje E.M., Hillegers Manon H.J., Koch Kathrin, Jurado María Ángeles, Mancini Matteo, Marqués-Iturria Idoia, Meinert Susanne, Ophoff Roel A., Reess Tim J., Repple Jonathan, Kahn René S., van den Heuvel Martijn P., 5 aug 2019, In: NATURE HUMAN BEHAVIOUR. 3 , p. 988-998 11 p.

Exploration of Shared Genetic Architecture Between Subcortical Brain Volumes and Anorexia Nervosa

Walton E., Hibar D., Yilmaz Z., Jahanshad N., Cheung J., Batury V. -L., Seitz J., Bulik C. M., Thompson P. M., Ehrlich Stefan, Hibar Derrek P., Stein Jason L., Renteria Miguel E., Arias-Vasquez Alejandro, Desrivieres Sylvane, Jahanshad Neda, Toro Roberto, Wittfeld Katharina, Abramovic Lucija, Andersson Micael, Aribisala Benjamin S., Armstrong Nicola J., Bernard Manon, Bohlken Marc M., Boks Marco P., Bralten Janita, Brown Andrew A., Chakravarty M. Mallar, Chen Qiang, Ching Christopher R. K., Cuellar-Partida Gabriel, Den Braber Anouk, Giddaluru Sudheer, Goldman Aaron L., Grimm Oliver, Guadalupe Tulio, Hass Johanna, Woldehawariat Girma, Klein Marieke, van Eijk Kristel R., Cahn Wiepke, Kahn Rene S., van Haren Neeltje E. M., Brouwer Rachel M., Pol Hilleke E. Hulshoff, Ophoff Roel, Adan Roger, Kas Martien, Koeleman Bobby, Ophoff Roel, 1 jul 2019, In: Molecular Neurobiology. 56 , p. 5146-5156 11 p.

The Association Between Familial Risk and Brain Abnormalities Is Disease Specific:An ENIGMA-Relatives Study of Schizophrenia and Bipolar Disorder

de Zwarte Sonja M C, Brouwer Rachel M, Agartz Ingrid, Alda Martin, Aleman André, Alpert Kathryn I, Bearden Carrie E, Bertolino Alessandro, Bois Catherine, Bonvino Aurora, Bramon Elvira, Buimer Elizabeth E L, Cahn Wiepke, Cannon Dara M, Cannon Tyrone D, Caseras Xavier, Castro-Fornieles Josefina, Chen Qiang, Chung Yoonho, De la Serna Elena, Di Giorgio Annabella, Doucet Gaelle E, Eker Mehmet Cagdas, Erk Susanne, Fears Scott C, Foley Sonya F, Frangou Sophia, Frankland Andrew, Fullerton Janice M, Glahn David C, Goghari Vina M, Goldman Aaron L, Gonul Ali Saffet, Gruber Oliver, de Haan Lieuwe, Hajek Tomas, Hawkins Emma L, Heinz Andreas, Hillegers Manon H J, Hulshoff Pol Hilleke, Hultman Christina M, Ingvar Martin, Johansson Viktoria, Jönsson Erik G, Kane Fergus, Kempton Matthew J, Koenis Marinka M G, van Os Jim, Kahn René, van Haren Neeltje E M, 13 jun 2019, In: Biological Psychiatry. 86 , p. 545-556 12 p.

Community housing: functional outcome of severe mental illness is associated with the personality traits of the case manager

Lodder Mandy, Schrijvers A. J. P., de Leeuw J. R. J., Brouwer R. M., Cahn W. 3 jun 2019, In: HOUSING CARE AND SUPPORT. 22 , p. 106-113 8 p.

High levels of several antipsychotics and antidepressants due to a pharmacogenetic cause:A case report

Mian Paola, Somers Metten, Berg Maarten Ten, Cahn Winnie, Wilting Ingeborg, Schaik Ron Van jun 2019, In: Pharmacogenomics. 20 , p. 567-570 4 p.

Publisher correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (vol 51, pg 659, 2019)

Huckins Laura M., Dobbyn Amanda, Ruderfer Douglas M., Hoffman Gabriel, Wang Weiqing, Pardiñas Antonio F., Rajagopal Veera M., Als Thomas D., T. Nguyen Hoang, Girdhar Kiran, Boocock James, Roussos Panos, Fromer Menachem, Kramer Robin, Domenici Enrico, Gamazon Eric R., Purcell Shaun, Johnson Jessica S., Shah Hardik R., Klein Lambertus L., Dang Kristen K., Logsdon Benjamin A., Mahajan Milind C., Mangravite Lara M., Toyoshiba Hiroyoshi, Gur Raquel E., Hahn Chang Gyu, Schadt Eric, Lewis David A., Haroutunian Vahram, Peters Mette A., Lipska Barbara K., Buxbaum Joseph D., Hirai Keisuke, Perumal Thanneer M., Essioux Laurent, Ripke Stephan, Neale Benjamin M., Corvin Aiden, Walters James T.R., Farh Kai How, Holmans Peter A., Lee Phil, Bulik-Sullivan Brendan, Collier David A., Cahn Wiepke, Chen Eric Y.H., Kahn Rene S., Van Os Jim, Ophoff Roel A., , , jun 2019, In: Nature Genetics. 51 , p. 1068-1068 1 p.

10Kin1day: A Bottom-Up Neuroimaging Initiative

van den Heuvel Martijn P. et al. 9 mei 2019, In: Frontiers in Neurology. 10 , p. 425 7 p.

Longitudinal evidence for a relation between depressive symptoms and quality of life in schizophrenia using structural equation modeling

van Rooijen Geeske, van Rooijen Maaike, Maat Arija, Vermeulen Jentien M., Meijer Carin J., Ruhe Henricus G., de Haan Lieuwe, Alizadeh Behrooz Z., Bartels-Velthuis Agna A., van Beveren Nico J., Bruggeman Richard, Cahn Wiepke, Delespaul Philippe, Myin-Germeys Inez, Kahn Rene S., Schirmbeck Frederike, Simons Claudia J. P., van Amelsvoort Therese, van Haren Neeltje E., van Os Jim, van Winkel Ruud, 29 apr 2019, In: Schizophrenia Research. 208 , p. 82-89

All Research Output (189)
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