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dr. T.B. Dansen

dr. T.B. Dansen

Associate Professor
  • Group Dansen, section Molecular Cancer Research

Research Programs

Strategic Program Cancer

Research Output (22)

Mitochondria-Derived H2O2 Promotes Symmetry Breaking of the C. elegans Zygote

De Henau Sasha, Pagès-Gallego Marc, Pannekoek Willem-Jan, Dansen Tobias B 7 apr 2020, In: Developmental Cell. 53 , p. 263-271.e6

GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay

Rumping Lynne, Tessadori Federico, Pouwels Petra J.W., Vringer Esmee, Wijnen Jannie P., Bhogal Alex A., Savelberg Sanne M.C., Duran Karen J., Bakkers Mark J.G., Ramos Rúben J.J., Schellekens Peter A.W., Kroes Hester Y., Klomp Dennis W.J., Black Graeme C.M., Taylor Rachel L., Bakkers Jeroen P.W., Prinsen Hubertus C.M.T., van der Knaap Marjo S., Dansen Tobias B., Rehmann Holger, Zwartkruis Fried J.T., Houwen Roderick H.J., van Haaften Gijs, Verhoeven-Duif Nanda M., Jans Judith J.M., van Hasselt Peter M. 1 jan 2019, In: Human Molecular Genetics. 28 , p. 96-104 9 p.

FOXO transcription factors both suppress and support breast cancer progression

Hornsveld Marten, Smits Lydia M.M., Meerlo Maaike, Van Amersfoort Miranda, Groot Koerkamp Marian J.A., van Leenen Dik, Kloet David E.A., Holstege Frank C.P., Derksen Patrick W.B., Burgering Boudewijn M.T., Dansen Tobias B. 1 mei 2018, In: Cancer Research. 78 , p. 2356-2369 14 p.

Re-evaluating the role of FOXOs in cancer

Hornsveld M., Dansen T. B., Derksen P. W., Burgering B. M.T. 1 jan 2017, In: Seminars in Cancer Biology. 50 , p. 90-100

Proteome-wide Changes in Protein Turnover Rates in C. elegans Models of Longevity and Age-Related Disease

Visscher Marieke, De Henau Sasha, Wildschut Mattheus H E, van Es Robert M., Dhondt Ineke, Michels Helen, Kemmeren Patrick, Nollen Ellen A., Braeckman Bart P., Burgering Boudewijn M T, Vos Harmjan R., Dansen Tobias B. 13 sep 2016, In: Cell Reports [E]. 16 , p. 3041-3051 11 p.

Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer

Hornsveld M, Tenhagen M, van de Ven R A, Smits A M M, van Triest M H, van Amersfoort M, Kloet D E A, Dansen T B, Burgering B M, Derksen P W B 1 sep 2016, In: Cell Death and Differentiation. 23 , p. 1483-1492 10 p.

The Hallmarks of Cancer from a Redox Perspective

Hornsveld Marten, Dansen Tobias B 20 aug 2016, In: Antioxidants & redox signaling. 25 , p. 300-325 26 p.

Covalent targeting of acquired cysteines in cancer

Visscher Marieke, Arkin Michelle R., Dansen Tobias B. 1 feb 2016, In: Current Opinion in Chemical Biology. 30 , p. 61-67 7 p.

The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex

van den Berg Maaike C W, van Gogh Inkie J A, Smits Alida M M, van Triest Miranda, Dansen Tobias B, Visscher Marieke, Polderman Paulien E, Vliem Marjolein J, Rehmann Holger, Burgering Boudewijn M T 15 jan 2016, In: Journal of Biological Chemistry. 291 , p. 1200

Evolutionary acquisition of cysteines determines FOXO paralog-specific redox signaling

Putker Marrit, Vos HR, Van Dorenmalen Kim, De Ruiter Hesther, Duran Ana G., Snel Berend, Burgering Boudewijn M T, Vermeulen M, Dansen TB 1 jan 2015, In: Antioxidants & redox signaling. 22 , p. 15-28 14 p.

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