prof. dr. J.H. (Joke) de Boer
prof. dr. J.H. (Joke) de Boer
- Department of Ophthalmology
Research Programs
Biography
Biography
Prof.dr. Joke de Boer is an ophthalmologist and acknowledged expert in inflammatory eye diseases with a special interest in noninfectious and infectious uveitis in adults and children. Noninfectious uveitis is a vision-threatening chronic, progressive inflammation of the interior eye. Current treatment strategies with immunosuppressive medications may fail to prevent the decline in visual function. Her research focusses on the underlying pathogenesis of noninfectious uveitis and development of new treatment strategies for this blinding disease in collaboration with the Laboratory of Translational Immunology. To this end, she uses the ‘Systems Medicine’ approach that combines in-depth phenotyping of the peripheral immune-compartment of patients and computational modeling of the derived high-throughput data to reveal the true perpetrating epigenetic mechanisms that drive noninfectious uveitis. The nature of this approach makes it very well suited for identifying novel biomarkers to improve treatment and disease outcome in patients with noninfectious uveitis in the near future. Other research topics are aqueous humor analysis in infectious uveitis in collaboration with the virology section of the department of medical microbiology . Joke de Boer is member of the International Uveitis Study Group, the national guideline committee for uveitis and the European guideline committee for uveitis associated with juvenile idiopathic arthritis.
Side Activities
Member of the International Uveitis Study Group
Member of tehe European paediatric ophthalmology society
Member of the Dutch Ophthalmology society
Member of the Dutch uveitis study group
Member of the Multinational Interdisciplinary working group of uveitis in children
Member of the Dutch "kennis agenda"of ophthalology
Member of James Lind aliance of Juvenile idiopathic artritis
Chair of addendum biologicals of the Dutch guideline of uveitis
Chair Quality committee Dutch Ophthalmology society
Board member of uveitis guideline committee Dutch Ophthalmology society
Member of the Fluorescein Angiography Netherlands club.
Member of the Dutch pediatric ophthalmology study group
Member of the European guideline committee for uveitis associated with juvenile idiopathic arthritis
Fellowship and Awards
1994 AER Montpellier, best paper award for “Low mature TGF-â2 in aqueous humour during uveitis”.
2011 ODAS price for paediatric ophthalmology
2011 The Clinical Uveitis Research Award from the European Uveitis Patient Interest Association
Research Output (123)
Wennink Roos A W, de Boer Joke H, Hiddingh Sanne, Haasnoot Anne-Mieke J W, Kalinina Ayuso Viera, de Hoop Talitha, van Setten Jessica, Spierings Eric, Kuiper Jonas J W 1 jul 2021, In: Investigative ophthalmology & visual science. 62 , p. 1-12
Wong Chung Justin E.R.E., Engin Ö, Wolfs T. F.W., Renson T. J.C., de Boer J. H. 3 apr 2021, In: The Lancet. 397 , p. e10
Venema Wouter J, Hiddingh Sanne, de Boer Joke H, Claas Frans H J, Mulder Arend, den Hollander Anneke I, Stratikos Efstratios, Sarkizova Siranush, van der Veken Lars T, Janssen George M C, van Veelen Peter A, Kuiper Jonas J W 25 feb 2021, In: Frontiers in Immunology. 12 15 p.
de Groot Evianne L., Ossewaarde - van Norel Jeannette, Ho Lintje, ten Dam - van Loon Ninette H., de Boer Joke H. dec 2020, In: American Journal of Ophthalmology Case Reports. 20 , p. 1-5
Wennink Roos A.W., Pandit Aridaman, Haasnoot Anne Mieke J.W., Hiddingh Sanne, Kalinina Ayuso Viera, Wulffraat Nico M., Vastert Bas J., Radstake Timothy R.D.J., de Boer Joke H., Kuiper Jonas J.W. 17 sep 2020, In: Frontiers in Immunology. 11
Brouwer Anna H, de Wit Gerard C, de Boer Joke H, van Genderen Maria M 1 jun 2020, In: Documenta Ophthalmologica. 140 , p. 201-209 9 p.
Laban Kamil G., Rijken Rianne, Hiddingh Sanne, Mertens Jorre S., van der Veen Rob L.P., Eenhorst Christine A.E., Pandit Aridaman, Radstake Timothy R.D.J., de Boer Joke H., Kalmann Rachel, Kuiper Jonas J.W. apr 2020, In: European Journal of Immunology. 50 , p. 548-557 10 p.
Spierings Julia, Sloeserwij Annemiek, Vianen Marieke E., de Boer Joke H., Sigurdsson Vigfus, van de Wijgert Janneke H.H.M., van Laar Jacob M. 26 mrt 2020, In: Clinical Immunology. 214
Brouwer Anna H, de Wit Gerard C, Ten Dam Ninette H, Wijnhoven Ralph, van Genderen Maria M, de Boer Joke H 19 mrt 2020, In: Acta Ophthalmologica. 98 , p. 627-633 7 p.
Buelens Tom, Ossewaarde-van Norel Jeannette, de Boer Joke H., Nubourgh Isabelle, Glibert Gérald, Kamgang Semeu Prochore, Fils Jean François, Caspers Laure, Postelmans Laurence, Willermain François 1 mrt 2020, In: Retina-The Journal of Retinal and Vitreous Diseases. 40 , p. 581-590 10 p.