prof. dr. R. de Bree MD

Full Professor
prof. dr. R. de Bree MD
  • Department of Head and Neck Oncology
  • MS Hoofd-Hals Chirurgische Oncologie

Research Programs

Strategic Program Cancer



Remco de Bree (1966) studied medicine in Utrecht, The Netherlands. His PhD research on the VU University Medical Center was about the clinical application of radiolabelled monoclonal antibodies in head and neck cancer patients. In 1999 he finished his training in otolaryngology. Thereafter, he was a fellow in head and neck surgery for 2 years at the same hospital, where he worked as a head and neck surgeon for 14 years and became full professor for clinical oncological research at the department of otolaryngology - head and neck surgery in 2006. Since 2015 he is full professor and head of the department of Head and Neck Surgical Oncology at the UMC Utrecht Cancer Center of the University Medical Center Utrecht, The Netherlands. His special interests are the clinical applications and improvements of diagnostic imaging techniques, sentinel node procedure, quality of life and reconstructive surgery in head and neck cancer patients. He has authored and co-authored over 200 articles in international peer-reviewed journals. He was the principal investigator and coordinator of several (inter)national multicenter trials, is a member of the Research steering committee of the Dutch Head and Neck Society (NWHHT), is a member of several editorial boards and member of the Cochrane Ear, Nose & Throat Disorders Group. 

Side Activities

Lid Clinical Audit Board van de Dutch Head and Neck Audit (DHNA)

Lid Scientific Advisory Board Dutch Oncology Research Platform (DORP)

Voorzitter Research stuurgroep Nederlandse  werkgroep Hoofd-Hals Tumoren (NWHHT)

Voorzitter Herziening richtlijn Hoofd-Halsoncologie

Lid kerngroep richtlijncommissie Nederlandse Werkgroep Hoofd-Hals Tumoren (NWHHT)

Lid Algemeen Bestuur Patiëntenvereniging Hoofd-Hals (PVHH)

Fellowship and Awards

1996 Best PhD thesis Dutch Otolaryngology Society

Research Output (314)

Prognostic imaging variables for recurrent laryngeal and hypopharyngeal carcinoma treated with primary chemoradiotherapy:A systematic review and meta-analysis

Smits Hilde J.G., Assili Sanam, Kauw Frans, Philippens Marielle E.P., de Bree Remco, Dankbaar Jan W. jul 2021, In: Head and Neck. 43 , p. 2202-2215 14 p.

Contemporary management of the neck in nasopharyngeal carcinoma

Ng Wai Tong, Tsang Raymond K.Y., Beitler Jonathan J., de Bree Remco, Coca-Pelaz Andrés, Eisbruch Avraham, Guntinas-Lichius Orlando, Lee Anne W.M., Mäkitie Antti A., Mendenhall William M., Nuyts Sandra, Rinaldo Alessandra, Robbins K. Thomas, Rodrigo Juan P., Silver Carl E., Simo Ricard, Smee Robert, Strojan Primož, Takes Robert P., Ferlito Alfio jun 2021, In: Head and Neck. 43 , p. 1949-1963 15 p.

Cost-utility and cost-effectiveness of a guided self-help head and neck exercise program for patients treated with total laryngectomy:Results of a multi-center randomized controlled trial

Jansen Femke, Coupé Veerle M.H., Eerenstein Simone E.J., Cnossen Ingrid C., van Uden-Kraan Cornelia F., de Bree Remco, Doornaert Patricia, Halmos György B., Hardillo José A.U., van Hinte Gerben, Honings Jimmie, Leemans C. René, Verdonck-de Leeuw Irma M. jun 2021, In: Oral Oncology. 117

Feasibility study of ultrasound-guided resection of tongue cancer with immediate specimen examination to improve margin control – Comparison with conventional treatment

de Koning Klijs J., Koppes Sjors A., de Bree Remco, Dankbaar Jan Willem, Willems Stefan M., van Es Robert J.J., Noorlag Rob mei 2021, In: Oral Oncology. 116 7 p.

Contralateral Regional Recurrence in Lateralized or Paramedian Early-Stage Oral Cancer Undergoing Sentinel Lymph Node Biopsy—Comparison to a Historic Elective Neck Dissection Cohort

Mahieu Rutger, den Toom Inne J., Boeve Koos, Lobeek Daphne, Bloemena Elisabeth, Donswijk Maarten L., de Keizer Bart, Klop W. Martin C., Leemans C. René, Willems Stefan M., Takes Robert P., Witjes Max J.H., de Bree Remco 23 apr 2021, In: Frontiers in oncology. 11 10 p.

Patterns, Predictors, and Prognostic Value of Skeletal Muscle Mass Loss in Patients with Locally Advanced Head and Neck Cancer Undergoing Cisplatin-Based Chemoradiotherapy

Chargi Najiba, Wegner Inge, Markazi Navid, Smid Ernst, de Jong Pim, Devriese Lot, de Bree Remco 18 apr 2021, In: Journal of Clinical medicine. 10

Electrochemotherapy in mucosal cancer of the head and neck:A systematic review

Strojan Primož, Grošelj Aleš, Serša Gregor, Plaschke Christina Caroline, Vermorken Jan B., Nuyts Sandra, de Bree Remco, Eisbruch Avraham, Mendenhall William M., Smee Robert, Ferlito Alfio 2 mrt 2021, In: Cancers. 13 15 p.

Cost-utility of an eHealth application 'Oncokompas' that supports cancer survivors in self-management:results of a randomised controlled trial

van der Hout A, Jansen F, van Uden-Kraan C F, Coupé V M, Holtmaat K, Nieuwenhuijzen G A, Hardillo J A, de Jong R J Baatenburg, Tiren-Verbeet N L, Sommeijer D W, de Heer K, Schaar C G, Sedee R J E, Bosscha K, van den Brekel M W M, Petersen J F, Westerman M, Honings J, Takes R P, Houtenbos I, van den Broek W T, de Bree R, Jansen P, Eerenstein S E J, Leemans C R, Zijlstra J M, Cuijpers P, van de Poll-Franse L V, Verdonck-de Leeuw I M feb 2021, In: Journal of cancer survivorship : research and practice. 15 , p. 77-86 10 p.

Presence of Human Papillomavirus and Epstein-Barr Virus, but Absence of Merkel Cell Polyomavirus, in Head and Neck Cancer of Non-Smokers and Non-Drinkers

Mulder Frans J, Klufah Faisal, Janssen Famke M E, Farshadpour Farzaneh, Willems Stefan M, de Bree Remco, Zur Hausen Axel, van den Hout Mari F C M, Kremer Bernd, Speel Ernst-Jan M 2021, In: Frontiers in oncology. 10

All research output

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