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dr. ing. S.C.A. (Saskia) de Jager

dr. ing. S.C.A. (Saskia) de Jager

Associate Professor
dr. ing. S.C.A. (Saskia) de Jager
  • Experimentele Afd. Cardiologie 2

Research Programs

Circulatory Health

Research Output (96)

Neutral Effects of Combined Treatment With GLP-1R Agonist Exenatide and MR Antagonist Potassium Canrenoate on Cardiac Function in Porcine and Murine Chronic Heart Failure Models

Demkes Evelyne J., Wenker Steven, Silvis Max J.M., van Nieuwburg Martijn M.J., Visser M. Joyce, Jansen Marlijn S., Brans Maike A.D., Velema Evelyn, Sluijter Joost P.G., Hoefer Imo E., de Kleijn Dominique P.V., Timmers Leo, de Jager Saskia C.A. 26 jul 2021, In: Frontiers in Pharmacology. 12 11 p.

Targeting inflammation after myocardial infarction:A therapeutic opportunity for extracellular vesicles?

Viola Margarida, de Jager Saskia C.A., Sluijter Joost P.G. 22 jul 2021, In: International journal of molecular sciences. 22

Mildly Increased Renin Expression in the Absence of Kidney Injury in the Murine Transverse Aortic Constriction Model

Wesseling Marian, Mulder Eva, Brans Maike A D, Kapteijn Daniek M C, Bulthuis Marian, Pasterkamp Gerard, Verhaar Marianne C, Danser A H Jan, van Goor Harry, Joles Jaap A, de Jager Saskia C A 15 jun 2021, In: Frontiers in Pharmacology. 12 , p. 1-11

Monocyte-chemoattractant protein-1 levels in human atherosclerotic lesions associate with plaque vulnerability

Georgakis Marios K., van der Laan Sander W., Asare Yaw, Mekke Joost M., Haitjema Saskia, Schoneveld Arjan H., de Jager Saskia C.A., Nurmohamed Nick S., Kroon Jeffrey, Stroes Erik S.G., de Kleijn Dominique P.V., de Borst Gert J., Maegdefessel Lars, Soehnlein Oliver, Pasterkamp Gerard, Dichgans Martin 8 apr 2021, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 41 , p. 2038-2048 11 p.

Growth differentiation factor 15 levels are similar in primary aldosteronism and essential hypertension and do not predict arterial inflammation

van der Heijden Charlotte D C C, Smeets Esther M M, Aarntzen Erik H J G, Wesseling Marian, de Jager Saskia C A, Riksen Niels P 1 mrt 2021, In: Journal of Hypertension. 39 , p. 593-596 4 p.

Damage-Associated Molecular Patterns in Myocardial Infarction and Heart Transplantation:The Road to Translational Success

Silvis Max J M, Kaffka Genaamd Dengler Selma E, Odille Clémence A, Mishra Mudit, van der Kaaij Niels P, Doevendans Pieter, Sluijter Joost P G, de Kleijn Dominique P V, de Jager Saskia C A, Bosch Lena, van Hout Gerardus P J 8 dec 2020, In: Frontiers in Immunology. 11

Myocardial infarction affects Cx43 content of extracellular vesicles secreted by cardiomyocytes

Martins-Marques Tania, Ribeiro-Rodrigues Teresa, de Jager Saskia C., Zuzarte Monica, Ferreira Cátia, Cruz Pedro, Reis Liliana, Baptista Rui, Gonçalves Lino, Sluijter Joost P.G., Girao Henrique 23 okt 2020, In: Life Science Alliance. 3 , p. 1-16

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

Depuydt Marie Ac, Prange Koen Hm, Slenders Lotte, Örd Tiit, Elbersen Danny, Boltjes Arjan, de Jager Saskia Ca, Asselbergs Folkert W, de Borst Gert J, Aavik Einari, Lönnberg Tapio, Lutgens Esther, Glass Christopher K, den Ruijter Hester M, Kaikkonen Minna U, Bot Ilze, Slütter Bram, van der Laan Sander W, Yla-Herttuala Seppo, Mokry Michal, Kuiper Johan, de Winther Menno Pj, Pasterkamp Gerard 28 sep 2020, In: Circulation research. 127 , p. 1437-1455 19 p.

Growth differentiation factor 15 in adverse cardiac remodelling:from biomarker to causal player

Wesseling Marian, de Poel Julius H.C. , de Jager Saskia C A 1 aug 2020, In: ESC heart failure. 7 , p. 1488-1501 14 p.

Both male and female obese ZSF1 rats develop cardiac dysfunction in obesity-induced heart failure with preserved ejection fraction

Nguyen Isabel T N, Brandt Maarten M, van de Wouw Jens, van Drie Ruben W A, Wesseling Marian, Cramer Maarten J, de Jager Saskia C A, Merkus Daphne, Duncker Dirk J, Cheng Caroline, Joles Jaap A, Verhaar Marianne C 6 mei 2020, In: PLoS ONE. 15

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