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dr. ing. S.C.A. (Saskia) de Jager

dr. ing. S.C.A. (Saskia) de Jager

Associate Professor

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Research Output (96)

Local inflammatory responses take their toll on the heart

de Jager Saskia C.A., Hoefer Imo E. 15 okt 2019, In: International Journal of Cardiology. 293 , p. 254-255 2 p.

Corrigendum to: Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure (vol 279, pg 141, 2019)

Bosch Lena, de Haan Judith J., Seijkens Tom T.P., van Tiel Claudia M., Brans Maike A.D., Pasterkamp Gerard, Lutgens Esther, de Jager Saskia C.A. 15 okt 2019, In: International Journal of Cardiology. 293 , p. 297-297 1 p.

Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells

Fontaine Margaux A.C., Westra Marijke M., Bot Ilze, Jin Han, Franssen Aimée J.P.M., Bot Martine, de Jager Saskia C.A., Dzhagalov Ivan, He You Wen, van Vlijmen Bart J.M., Gijbels Marion J.J., Reutelingsperger Chris P., van Berkel Theo J.C., Sluimer Judith C., Temmerman Lieve, Biessen Erik A.L. 10 okt 2019, In: Scientific Reports. 9

Increased circulating IgG levels, myocardial immune cells and IgG deposits support a role for an immune response in pre- and end-stage heart failure

van den Hoogen Patricia, de Jager Saskia C.A., Huibers Manon M.H., Schoneveld Arjan H., Puspitasari Yustina M., Valstar Gideon B., Oerlemans Marish I.F.J., de Weger Roel A., Doevendans Pieter A., den Ruijter Hester M., Laman Jon D., Vink Aryan, Sluijter Joost P.G. 26 sep 2019, In: Journal of Cellular and Molecular Medicine. 23 , p. 7505-7516 12 p.

Circulating CD14+CD16- classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients

Meeuwsen John A.L., de Vries Judith J., van Duijvenvoorde Amerik, van der Velden Saskia, van der Laan Sander W., van Koeverden Ian D., van de Weg Sander M., de Borst Gert J., de Winther Menno P.J., Kuiper Johan, Pasterkamp Gerard, Hoefer Imo E., de Jager Saskia C.A., 1 feb 2019, In: Journal of Molecular and Cellular Cardiology. 127 , p. 260-269 10 p.

Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure

Bosch Lena, de Haan Judith, Seijkens Tom, van Tiel Claudia, Brans Maike, Pasterkamp Gerard, Lutgens Esther, de Jager Saskia 1 jan 2019, In: International Journal of Cardiology. 279 , p. 141-144 4 p.

Potential of mesenchymal- and cardiac progenitor cells for therapeutic targeting of B-cells and antibody responses in end-stage heart failure

van den Hoogen Patricia, de Jager Saskia C A, Mol Emma A, Schoneveld Arjan S, Huibers Manon M H, Vink Aryan, Doevendans Pieter A, Laman Jon D, Sluijter Joost P G 1 jan 2019, In: PLoS ONE. 14

Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions

Siemelink MA, van der Laan S.W., Haitjema S, van Koeverden ID, Schaap J, Wesseling M, de Jager SCA, Mokry M, Van Iterson Maarten, Dekkers Koen F, Luijk René, Foroughi Asl Hassan, Björkegren Johan L M, Aavik Einari, Ylä-Herttuala Seppo, de Borst GJ, Asselbergs FW, el Azzouzi H, den Ruijter HM, Heijmans Bastiaan T., Pasterkamp G 1 sep 2018, In: Circ Genom Precis Med. 11

Janus revisited:The intricate role of the immune system in neovascularization

Hoefer Imo E., de Jager Saskia C.A. 1 jun 2018, In: International Journal of Cardiology. 260 , p. 193-194 2 p.

Noncanonical NF-κB signaling in microvessels of atherosclerotic lesions is associated with inflammation, atheromatous plaque morphology and myocardial infarction

Maracle Chrissta X., Agca Rabia, Helder Boy, Meeuwsen John A.L., Niessen Hans W.M., Biessen Erik A.L., de Winther Menno P.J., de Jager Saskia C.A., Nurmohamed Mike T., Tas Sander W. 1 mrt 2018, In: Atherosclerosis. 270 , p. 33-41 9 p.

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