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dr. ing. S.C.A. (Saskia) de Jager

dr. ing. S.C.A. (Saskia) de Jager

Associate Professor

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Research Output (111)

Immunomodulation in Heart Failure with Preserved Ejection Fraction:Current State and Future Perspectives

Kessler Elise L., Oerlemans Martinus I.F.J., van den Hoogen Patricia, Yap Carmen, Sluijter Joost P.G., de Jager Saskia C.A. 2020, In: Journal of Cardiovascular Translational Research. 14 , p. 63-74 12 p.

A Pro-Inflammatory Biomarker-Profile Predicts Amputation-Free Survival in Patients with Severe Limb Ischemia

Gremmels Hendrik, Teraa Martin, de Jager Saskia C.A., Pasterkamp Gerard, de Borst Gert J., Verhaar Marianne C. 1 Dec 2019, In: Scientific Reports. 9

Platelet RNA modules point to coronary calcification in asymptomatic women with former preeclampsia

Hartman Robin J.G., Korporaal Suzanne J.A., Mokry Michal, de Jager Saskia C.A., Meeuwsen John A.L., van der Laan Sander W., Lansu Nico R., Zoet Gerbrand A., Pasterkamp Gerard, Urbanus Rolf T., Hoefer Imo E., Franx Arie, Velthuis Birgitta K., van Rijn Bas B., den Ruijter Hester M., 1 Dec 2019, In: Atherosclerosis. 291 , p. 114-121 8 p.

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

Frodermann Vanessa, Rohde David, Courties Gabriel, Severe Nicolas, Schloss Maximilian J., Amatullah Hajera, McAlpine Cameron S., Cremer Sebastian, Hoyer Friedrich F., Ji Fei, van Koeverden Ian D., Herisson Fanny, Honold Lisa, Masson Gustavo Santos, Zhang Shuang, Grune Jana, Iwamoto Yoshiko, Schmidt Stephen P., Wojtkiewicz Gregory R., Lee I. Hsiu, Gustafsson Karin, Pasterkamp Gerard, de Jager Saskia C.A., Sadreyev Ruslan I., MacFadyen Jean, Libby Peter, Ridker Paul, Scadden David T., Naxerova Kamila, Jeffrey Kate L., Swirski Filip K., Nahrendorf Matthias 1 Nov 2019, In: Nature Medicine. 25 , p. 1761-1771 11 p.

Local inflammatory responses take their toll on the heart

de Jager Saskia C.A., Hoefer Imo E. 15 Oct 2019, In: International Journal of Cardiology. 293 , p. 254-255 2 p.

Corrigendum to: Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure (vol 279, pg 141, 2019)

Bosch Lena, de Haan Judith J., Seijkens Tom T.P., van Tiel Claudia M., Brans Maike A.D., Pasterkamp Gerard, Lutgens Esther, de Jager Saskia C.A. 15 Oct 2019, In: International Journal of Cardiology. 293 , p. 297-297 1 p.

Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells

Fontaine Margaux A.C., Westra Marijke M., Bot Ilze, Jin Han, Franssen Aimée J.P.M., Bot Martine, de Jager Saskia C.A., Dzhagalov Ivan, He You Wen, van Vlijmen Bart J.M., Gijbels Marion J.J., Reutelingsperger Chris P., van Berkel Theo J.C., Sluimer Judith C., Temmerman Lieve, Biessen Erik A.L. 10 Oct 2019, In: Scientific Reports. 9

Increased circulating IgG levels, myocardial immune cells and IgG deposits support a role for an immune response in pre- and end-stage heart failure

van den Hoogen Patricia, de Jager Saskia C.A., Huibers Manon M.H., Schoneveld Arjan H., Puspitasari Yustina M., Valstar Gideon B., Oerlemans Marish I.F.J., de Weger Roel A., Doevendans Pieter A., den Ruijter Hester M., Laman Jon D., Vink Aryan, Sluijter Joost P.G. 26 Sep 2019, In: Journal of Cellular and Molecular Medicine. 23 , p. 7505-7516 12 p.

Circulating CD14+CD16- classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients

Meeuwsen John A.L., de Vries Judith J., van Duijvenvoorde Amerik, van der Velden Saskia, van der Laan Sander W., van Koeverden Ian D., van de Weg Sander M., de Borst Gert J., de Winther Menno P.J., Kuiper Johan, Pasterkamp Gerard, Hoefer Imo E., de Jager Saskia C.A., 1 Feb 2019, In: Journal of Molecular and Cellular Cardiology. 127 , p. 260-269 10 p.

Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure

Bosch Lena, de Haan Judith, Seijkens Tom, van Tiel Claudia, Brans Maike, Pasterkamp Gerard, Lutgens Esther, de Jager Saskia 1 Jan 2019, In: International Journal of Cardiology. 279 , p. 141-144 4 p.

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