prof. dr. A.M.G.A. (Anne Marie) de Smet

prof. dr. A.M.G.A. (Anne Marie) de Smet

Full Professor
prof. dr. A.M.G.A. (Anne Marie) de Smet
  • Division of Anesthesiology, Intensive Care and Emergency Medicine - Medical
  • Division of Anesthesiology, Intensive Care and Emergency Medicine - Medical



Anne Marie de Smet (1959) was trained as an anesthesiologist (University Hospital Groningen) and intensivist (Onze Lieve Vrouwe Gasthuis, Amsterdam). She became a staff member of the Division of Perioperative care and Emergency medicine of the University Medical Center Utrecht in 1993. Within the Division, she was responsible for the Intensive Care Unit from 1995 until 2005. In 2002 she started the scientific investigation on infection prevention which lead to a thesis and PhD degree (2009). She held positions in the board of the ‘Staff members’ of the University Medical Center Utrecht from 2000 to 2004 and was active in the first committee on patient safety in the UMCU. Moreover she served as a board member of the Dutch Society of Intensive Care between 2002 and 2008. From August 2006 on,  she combined clinical research on SDD in Utrecht with a staff membership in the Intensive Care Unit of the CWZ  in Nijmegen. In October 2008 she returned to the Intensive Care of the OLVG in Amsterdam.

In 2011 she accepted a position in the UMCG as the chair of the department of Critical Care.

In 2019 she returned to the UMCU as Chair Division of Anesthesiology, Intensive Care and Emergency Medicine. Her fields of interest are infection prevention and patient safety with as main researchfield infectionprevention in critically ill patients.

Side Activities


Juni 2018-heden

Research Output (61)

Cohort profile of PLUTO:a perioperative biobank focusing on prediction and early diagnosis of postoperative complications

de Mul Nikki, Verlaan Diede, Ruurda Jelle P, van Grevenstein Wilhelmina M U, Hagendoorn Jeroen, de Borst Gert-Jan, Vriens Menno R, de Bree Remco, Zweemer Ronald P, Vogely Charles, Haitsma Mulier Jelle L G, Vernooij Lisette M, Reitsma Johannes B, de Zoete Marcel R, Top Janetta, Kluijtmans Jan A J, Hoefer Imo E, Noordzij Peter, Rettig Thijs, Marsman Marije, de Smet Anne Marie G A, Derde Lennie, van Waes Judith, Rijsdijk Mienke, Schellekens Willem Jan M, Bonten Marc J M, Slooter Arjen J C, Cremer Olaf L 19 Apr 2023, In: BMJ Open. 13 16 p.

Sputum proteome signatures of mechanically ventilated intensive care unit patients distinguish samples with or without anti-pneumococcal activity

Seinen Jolien, Engelke Rudolf, Abdullah Mohammed R., Voß Franziska, Michalik Stephan, Dhople Vishnu M., Dieperink Willem, de Smet Anne Marie G.A., Völker Uwe, van Dijl Jan Maarten, Schmidt Frank, Hammerschmidt Sven 2 Mar 2021, In: mSystems. 6

Prevention of severe infectious complications after colorectal surgery using oral non-absorbable antimicrobial prophylaxis:Results of a multicenter randomized placebo-controlled clinical trial

Mulder Tessa, Kluytmans-Van Den Bergh Marjolein, Vlaminckx Bart, Roos Daphne, De Smet Anne Marie, De Vos Tot Nederveen Cappel Robert, Verheijen Paul, Brandt Alexandra, Smits Anke, Van Der Vorm Eric, Bathoorn Erik, Van Etten Boudewijn, Veenemans Jacobien, Weersink Annemarie, Vos Margreet, Van 'T Veer Nils, Nikolakopoulos Stavros, Bonten Marc, Kluytmans Jan 15 Jun 2020, In: Antimicrobial Resistance and Infection Control. 9 , p. 1-11

Yeast Infections after Esophagectomy:A Retrospective Analysis

Heuker Marjolein, Koser Usma, Ott Alewijn, Karrenbeld Arend, van Dijl Jan Maarten, van Dam Gooitzen M., de Smet Anne Marie G.A., van Oosten Marleen 9 Mar 2020, In: Scientific Reports. 10 8 p.

Marked Changes in Gut Microbiota in Cardio-Surgical Intensive Care Patients:A Longitudinal Cohort Study

Aardema Heleen, Lisotto Paola, Kurilshikov Alexander, Diepeveen Janneke R.J., Friedrich Alex W., Sinha Bhanu, de Smet Anne Marie G.A., Harmsen Hermie J.M. 15 Jan 2020, In: Frontiers in cellular and infection microbiology. 9 , p. 467

Heterogeneous antimicrobial activity in broncho-alveolar aspirates from mechanically ventilated intensive care unit patients

Seinen Jolien, Dieperink Willem, Mekonnen Solomon A., Lisotto Paola, Harmsen Hermie J.M., Hiemstra Bart, Ott Alewijn, Schultz Daniel, Lalk Michael, Oswald Stefan, Hammerschmidt Sven, de Smet Anne Marie G.A., van Dijl Jan Maarten Dec 2019, In: Virulence. 10 , p. 879-891 13 p.

Cost-effectiveness of selective digestive decontamination (SDD) versus selective oropharyngeal decontamination (SOD) in intensive care units with low levels of antimicrobial resistance:an individual patient data meta-analysis

Van Hout Denise, Plantinga Nienke L., Bruijning-Verhagen Patricia C., Oostdijk Evelien A.N., De Smet Anne Marie G.A., De Wit G. Ardine, Bonten Marc J.M., Van Werkhoven Cornelis H. 6 Sep 2019, In: BMJ Open. 9

Emergency Department to ICU Time Is Associated With Hospital Mortality:A Registry Analysis of 14,788 Patients From Six University Hospitals in the Netherlands

Groenland Carline N.L., Termorshuizen Fabian, Rietdijk Wim J.R., Van Den Brule Judith, Dongelmans Dave A., De Jonge Evert, De Lange Dylan W., De Smet Anne Marie G.A., De Keizer Nicolette F., Weigel Joachim D., Jewbali Lucia S.D., Boersma Eric, Den Uil Corstiaan A. 7 Aug 2019, In: Critical Care Medicine. 47 , p. 1564-1571 8 p.

ESCMID-EUCIC clinical guidelines on decolonization of multidrug-resistant Gram-negative bacteria carriers

Tacconelli E., Mazzaferri F., de Smet A. M., Bragantini D., Eggimann P., Huttner B. D., Kuijper E. J., Lucet J. C., Mutters N. T., Sanguinetti M., Schwaber M. J., Souli M., Torre-Cisneros J., Price J. R., Rodríguez-Baño J. Jul 2019, In: Clinical Microbiology and Infection. 25 , p. 807-817 11 p.

Cumulative Prognostic Score Predicting Mortality in Patients Older Than 80 Years Admitted to the ICU

de Lange Dylan W., Brinkman Sylvia, Flaatten Hans, Boumendil Ariane, Morandi Alessandro, Andersen Finn H., Artigas Antonio, Bertolini Guido, Cecconi Maurizio, Christensen Steffen, Faraldi Loredana, Fjølner Jesper, Jung Christian, Marsh Brian, Moreno Rui, Oeyen Sandra, Öhman Christina Agvald, Bollen Pinto Bernardo, de Smet Anne Marie G.A., Soliman Ivo W., Szczeklik Wojciech, Valentin Andreas, Watson Ximena, Zafeiridis Tilemachos, Guidet Bertrand, Schmutz René, Wimmer Franz, Eller Philipp, Joannidis Michael, De Buysscher Pieter, De Neve Nikolaas, Swinnen Walter, Abraham Paul, Hergafi Leila, Schefold Joerg C., Biskup Ewelina, Piza Petr, Taliadoros Ioannis, Dey Nilanjan, Sølling Christoffer, Rasmussen Bodil Steen, Forceville Xavier, Besch Guillaume, Mentec Herve, Michel Philippe, Mateu Philippe, Michel Philippe, Vettoretti Lucie, Bourenne Jeremy, Marin Nathalie, 12 Apr 2019, In: Journal of the American Geriatrics Society. 67 , p. 1263-1267 5 p.

All research output

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